Pharmacology Quiz: Peptic Ulcer Treatment
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Questions and Answers

What is the hormone that increases with the long-term use of omeprazole in a patient with peptic ulcer?

  • Gastrin (correct)
  • Motilin
  • Ghrelin
  • Serotonin
  • Which of the following is a characteristic of achalasia?

  • Transient relaxation of the LES
  • Increased motilin levels
  • Failure of the LES to relax (correct)
  • Relaxation of the lower esophageal sphincter (LES)
  • What is the likely outcome of dysplasia in the gastric region?

  • Helicobacter pylori infection
  • Gastroesophageal reflux disease
  • Gastric ulcer
  • Gastric cancer (correct)
  • Which vitamin is related to NL1?

    <p>Vitamin B12</p> Signup and view all the answers

    What is the columnar epithelium that replaces the normal squamous epithelium in the esophagus in Barrett's esophagus?

    <p>Columnar epithelium</p> Signup and view all the answers

    What is the relationship between NL1 and H. pylori?

    <p>H. pylori is a cause of NL1</p> Signup and view all the answers

    What is the relationship between NL1 and SCC?

    <p>NL1 is a precursor to SCC</p> Signup and view all the answers

    What is the significance of the year 2561 in NL1?

    <p>It is a reference to a specific study or publication</p> Signup and view all the answers

    What is the term for the abnormal relaxation of the lower esophageal sphincter (LES) that leads to gastroesophageal reflux disease (GERD)?

    <p>Transient relaxation of the LES</p> Signup and view all the answers

    What is the term for the nerve plexus that is intrinsic to the gastrointestinal tract and plays a key role in regulating gut motility?

    <p>Myenteric plexus</p> Signup and view all the answers

    Study Notes

    Peptic Ulcer

    • Omeprazole increases gastrin levels.

    Lower Esophageal Sphincter (LES)

    • Transient relaxation of LES is related to GERD.

    Gastroesophageal Reflux Disease (GERD)

    • GERD can lead to Barrett's esophagus, a chronic condition.

    Barrett's Esophagus

    • Characterized by replacement of normal squamous epithelium with columnar epithelium.

    Achalasia

    • Causes relaxation of the LES, leading to dysphagia.

    Gut-Brain Axis

    • Intrinsic myenteric plexus plays a role in gut-brain communication.

    Gut Hormones

    • Gastrin, motilin, and ghrelin are important hormones in the gut.
    • Omeprazole increases gastrin levels.

    Cancer

    • Helicobacter pylori infection can lead to dysplasia and eventually gastric cancer.

    Vitamin Deficiency

    • Pernicious anemia can lead to vitamin B12 deficiency.

    Gut Motility

    • Relaxation of the LES can lead to GERD.

    Gut Nervous System

    • Intrinsic myenteric plexus is part of the enteric nervous system.
    • damage to the intrinsic myenteric plexus can lead to achalasia.

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    A patient with peptic ulcer is treated with omeprazole for 6 months. Which blood hormone level increases as a result?

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