Podcast
Questions and Answers
What is the hormone that increases with the long-term use of omeprazole in a patient with peptic ulcer?
What is the hormone that increases with the long-term use of omeprazole in a patient with peptic ulcer?
- Gastrin (correct)
- Motilin
- Ghrelin
- Serotonin
Which of the following is a characteristic of achalasia?
Which of the following is a characteristic of achalasia?
- Transient relaxation of the LES
- Increased motilin levels
- Failure of the LES to relax (correct)
- Relaxation of the lower esophageal sphincter (LES)
What is the likely outcome of dysplasia in the gastric region?
What is the likely outcome of dysplasia in the gastric region?
- Helicobacter pylori infection
- Gastroesophageal reflux disease
- Gastric ulcer
- Gastric cancer (correct)
Which vitamin is related to NL1?
Which vitamin is related to NL1?
What is the columnar epithelium that replaces the normal squamous epithelium in the esophagus in Barrett's esophagus?
What is the columnar epithelium that replaces the normal squamous epithelium in the esophagus in Barrett's esophagus?
What is the relationship between NL1 and H. pylori?
What is the relationship between NL1 and H. pylori?
What is the relationship between NL1 and SCC?
What is the relationship between NL1 and SCC?
What is the significance of the year 2561 in NL1?
What is the significance of the year 2561 in NL1?
What is the term for the abnormal relaxation of the lower esophageal sphincter (LES) that leads to gastroesophageal reflux disease (GERD)?
What is the term for the abnormal relaxation of the lower esophageal sphincter (LES) that leads to gastroesophageal reflux disease (GERD)?
What is the term for the nerve plexus that is intrinsic to the gastrointestinal tract and plays a key role in regulating gut motility?
What is the term for the nerve plexus that is intrinsic to the gastrointestinal tract and plays a key role in regulating gut motility?
Study Notes
Peptic Ulcer
- Omeprazole increases gastrin levels.
Lower Esophageal Sphincter (LES)
- Transient relaxation of LES is related to GERD.
Gastroesophageal Reflux Disease (GERD)
- GERD can lead to Barrett's esophagus, a chronic condition.
Barrett's Esophagus
- Characterized by replacement of normal squamous epithelium with columnar epithelium.
Achalasia
- Causes relaxation of the LES, leading to dysphagia.
Gut-Brain Axis
- Intrinsic myenteric plexus plays a role in gut-brain communication.
Gut Hormones
- Gastrin, motilin, and ghrelin are important hormones in the gut.
- Omeprazole increases gastrin levels.
Cancer
- Helicobacter pylori infection can lead to dysplasia and eventually gastric cancer.
Vitamin Deficiency
- Pernicious anemia can lead to vitamin B12 deficiency.
Gut Motility
- Relaxation of the LES can lead to GERD.
Gut Nervous System
- Intrinsic myenteric plexus is part of the enteric nervous system.
- damage to the intrinsic myenteric plexus can lead to achalasia.
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Description
A patient with peptic ulcer is treated with omeprazole for 6 months. Which blood hormone level increases as a result?
