Pharmacology Quiz
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Questions and Answers

Which type of drug binds to receptors and decreases or blocks the action of an antagonist?

  • Receptor
  • Antagonist (correct)
  • Ligand
  • Agonist
  • What is the measure of how much drug is required to produce a given effect?

  • Efficacy
  • Potency (correct)
  • Therapeutic Index
  • Lethal Dose
  • What is the minimum dose that will kill 50% of persons in a population?

  • LD50 (correct)
  • ED50
  • TI50
  • TD50
  • A drug with high efficacy but low potency would require what to produce a maximum response?

    <p>A higher dose</p> Signup and view all the answers

    What indicates a relatively low incidence of side effects at usual doses?

    <p>High therapeutic index</p> Signup and view all the answers

    What therapeutic index indicates a drug to be very safe?

    <p>4</p> Signup and view all the answers

    Which factor does not affect drug absorption?

    <p>Second pass metabolism</p> Signup and view all the answers

    What is the dose of a drug that will produce a specific effect in 50% of the population?

    <p>ED50</p> Signup and view all the answers

    Which of the following factors does not affect drug absorption?

    <p>Ruth of administration</p> Signup and view all the answers

    What is the term that describes the amount of drug that is actually available to the body after administration?

    <p>Bioavailability</p> Signup and view all the answers

    Which factor affects drug absorption by reducing the amount of drug available to the body?

    <p>First pass metabolism</p> Signup and view all the answers

    What is the term that describes the process by which a drug is absorbed into the bloodstream and then transported to the liver for metabolism?

    <p>First pass metabolism</p> Signup and view all the answers

    Which of the following options is not a factor that affects drug absorption?

    <p>Aquarius aqueous solution</p> Signup and view all the answers

    Study Notes

    Pharmacology Concepts

    • A drug that binds to receptors and decreases or blocks the action of an antagonist is an antagonist.
    • Agonist is the correct answer, as it binds to receptors and increases or mimics the action of an agonist.

    Pharmacological Measures

    • Efficacy represents the maximum response that can be produced by a drug.
    • Potency represents the dose of a drug required to produce a given effect.

    Toxicology

    • LD50 (Lethal Dose 50) represents the minimum dose that will kill 50% of persons in a population.
    • ED50 (Effective Dose 50) represents the dose of a drug that will produce a specific effect in 50% of the population.
    • TD50 (Toxic Dose 50) represents the minimum dose that will produce a specific toxic effect in 50% of the population.

    Pharmacodynamic Properties

    • A drug with high efficacy but low potency will produce a higher level of response with a greater dose.
    • A potent drug reaches its maximum response at a lower dose.

    Therapeutic Index

    • Low therapeutic index indicates a relatively high incidence of side effects at usual doses.
    • High therapeutic index indicates a low incidence of side effects.

    Therapeutic Index and Safety

    • A therapeutic index of 1 indicates a low margin of safety.
    • A therapeutic index of 4 indicates a high margin of safety and the drug is very safe.

    Factors Affecting Drug Absorption

    • Liquid solubility affects drug absorption.
    • Bioavailability affects drug absorption.
    • First pass metabolism affects drug absorption.
    • Route of administration affects drug absorption.
    • Aqueous solubility is not a factor affecting drug absorption.

    Factors Affecting Drug Absorption

    • Liquid solubility is a factor that affects drug absorption.
    • Bioavailability is a factor that affects drug absorption.
    • First pass metabolism is a factor that affects drug absorption.
    • Route of administration is a factor that affects drug absorption.
    • There is no such term as "Aquarius aqueous solution" in pharmacology, so it's the exception.
    • There is no such term as "Second pass metabolism" in pharmacology, so it's not a valid factor affecting drug absorption.

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    Description

    Multiple choice questions on pharmacology concepts, including antagonists, agonists, efficacy, and potency.

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