Questions and Answers
What is the therapeutic class of Omeprazole?
What is the pharmacologic class of Omeprazole?
What is the expected pharmacological action of Omeprazole?
Binds to an enzyme on gastric parietal cells in the presence of acidic gastric pH, preventing the final transport of H+ ions into the gastric lumen.
What are the therapeutic uses of Omeprazole?
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What are some side/adverse effects of Omeprazole?
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How should Omeprazole be administered?
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Omeprazole interacts with _____ such as antifungal agents and warfarin.
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Hypersensitivity is a contraindication/precaution of Omeprazole.
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What nursing interventions are important for patients taking Omeprazole?
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How can the effectiveness of Omeprazole be evaluated?
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What should clients be educated about when taking Omeprazole?
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Study Notes
Omeprazole Overview
- Therapeutic class: Antiulcer agents, utilized in managing conditions related to excess gastric acid.
- Pharmacologic class: Proton pump inhibitors, preventing acid secretion by blocking the proton pump in gastric parietal cells.
Pharmacological Action
- Mechanism: Binds to an enzyme on gastric parietal cells at acidic pH, inhibiting H+ ion transport into the gastric lumen, thus reducing acid secretion.
Therapeutic Uses
- Indications: Effective in healing duodenal ulcers and lowering gastric acid accumulation, leading to reduced gastroesophageal reflux symptoms.
Side/Adverse Effects
- Severe risks: Can cause pseudomembranous colitis and may lead to abdominal pain.
Medication Administration
- Dosage form: Administer orally before meals, preferably in the morning.
- Instructions: Swallow capsules whole; do not crush or chew. Capsules can be opened and sprinkled on cool applesauce for ease of intake.
Drug Interactions
- Significant interactions: Antifungal agents, diazepam, digoxin, flurazepam, triazolam, cyclosporine, phenytoin, and warfarin may have altered effects when taken with Omeprazole.
Contraindications and Precautions
- Key contraindications: Hypersensitivity to the drug and presence of liver disease should be carefully considered before prescribing.
Nursing Interventions
- Monitoring: Assess bowel function regularly. Advise immediate reporting of gastrointestinal symptoms such as diarrhea, abdominal cramping, fever, or bloody stools.
Effectiveness Evaluation
- Indicators of success: Look for a reduction in abdominal pain, prevention of gastric irritation bleeding, and improvement in symptoms associated with GERD and erosive esophagitis.
Client Education
- Important advisories: Be aware of possible drowsiness or dizziness. Avoid alcohol and NSAIDs, including aspirin. Report early signs of serious side effects, such as black, tarry stools, severe diarrhea, abdominal pain, persistent headache, or fever.
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Description
This quiz provides detailed flashcards about Omeprazole, including its therapeutic and pharmacologic classes as well as its expected pharmacological action. Ideal for students in pharmacology, it reinforces important concepts related to this antiulcer medication.
