Pharmacology of Piperazine

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Questions and Answers

What is the action of the mentioned medication against ascariasis?

  • It is active (correct)
  • It is ineffective against ascariasis
  • It is inactive
  • It is partially active

What is the effectiveness of the mentioned medication against filariasis?

  • Partially effective
  • Effective against various forms (correct)
  • Not effective at all
  • Only effective against ascariasis

Which of the following medications is a Benzimidazole derivative?

  • Ivermectin
  • Pyrantel Pamoate
  • Thiabendazole (correct)
  • Mebeverine

What is the effect of piperazine on the ascaris muscle?

<p>It blocks the response to acetylcholine (D)</p> Signup and view all the answers

Which of the following medications is not mentioned in the text?

<p>Albendazole (D)</p> Signup and view all the answers

What is the name of the medication mentioned in the text that is effective against various forms of filariasis?

<p>NMB (B)</p> Signup and view all the answers

What is the outcome of piperazine blocking the response of the ascaris muscle to acetylcholine?

<p>Flaccid paralysis in the worm (B)</p> Signup and view all the answers

What is the neurotransmitter involved in the response of the ascaris muscle?

<p>Acetylcholine (D)</p> Signup and view all the answers

What type of paralysis is caused by piperazine in the worm?

<p>Flaccid paralysis (B)</p> Signup and view all the answers

What is the mechanism of action of piperazine on the ascaris muscle?

<p>It blocks the response of the muscle to acetylcholine (C)</p> Signup and view all the answers

What is the chemical structure of Praziquantil?

<p>2-(Cyclohexylcarbonyl)-1, 2, 3, 6, 7, 11b-hexahydro-4Hpyrazino[2,1-a]isoquinolin-4one (C)</p> Signup and view all the answers

What type of derivative is Praziquantil?

<p>Salicylamide derivative (A)</p> Signup and view all the answers

What page is PCH606 on?

<p>Page 1 (D)</p> Signup and view all the answers

Which of the following is Niclosamide?

<p>An antiprotozoal (A)</p> Signup and view all the answers

What is the classification of PCH606?

<p>Antiprotozoal (B)</p> Signup and view all the answers

What is the reason quinine is still used for malaria treatment?

<p>It is effective against malaria caused by P. falciparum resistant to other agents (A)</p> Signup and view all the answers

What type of malaria is quinine indicated for?

<p>Malaria caused by P. falciparum resistant to chloroquine (D)</p> Signup and view all the answers

What is the type of drug that quinine is an alternative to?

<p>Chloroquine (A)</p> Signup and view all the answers

What is the primary advantage of using quinine for malaria treatment?

<p>It is effective against malaria resistant to other agents (C)</p> Signup and view all the answers

What type of parasite is quinine effective against?

<p>P. falciparum (B)</p> Signup and view all the answers

What type of compound is ivermectin?

<p>Semisynthetic macrocyclic lactone (A)</p> Signup and view all the answers

What is ivermectin commonly used to treat?

<p>Helminth infestations (B)</p> Signup and view all the answers

What types of helminth infestations is ivermectin effective against?

<p>Strongyloidiasis and onchocerciasis (C)</p> Signup and view all the answers

What is a characteristic of ivermectin's chemical structure?

<p>It has a macrocyclic lactone structure (A)</p> Signup and view all the answers

What is ivermectin's status as a medication?

<p>It is a semisynthetic derivative (B)</p> Signup and view all the answers

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