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Pharmacology of Pain Management

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DauntlessShark9501
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15 Questions

What is the first step in managing pain?

Non-opioid analgesics such as aspirin or paracetamol

What type of pain is treated with antidepressants, anticonvulsants, gabapentin, pregabalin, and ketamine?

Neuropathic pain

What is used for moderate-to-severe pain?

Strong opioids with or without non-opioid

Which medication is not used for neuropathic pain?

Codeine

What type of receptor does ketamine act on?

NMDA receptor

What type of pain is typically treated with non-opioid analgesics?

Mild pain

Which type of medication is often used in step two of pain management?

Mild opioids

What type of medication is useful for treating neuropathic pain?

Antidepressants and anticonvulsants

Which receptor does gabapentin act on?

GABA receptors

What type of pain is typically treated with strong opioids?

Moderate-to-severe pain

What is the main difference between step two and step three in pain management?

The severity of pain

Which of the following medications is not typically used in step one of pain management?

Codeine

What is the primary mechanism of action for carbamazepine in treating neuropathic pain?

Blocking NaCh and GABA-R

What is the common characteristic of medications used in step three of pain management?

They are all strong opioids

Which receptor is not involved in the treatment of neuropathic pain?

Dopamine receptors

Study Notes

Pain Management Steps

  • Step one: Non-opioid analgesics are used, including aspirin, paracetamol, and non-steroidal anti-inflammatory drugs (NSAIDs)
  • Step two: Mild opioids, such as codeine, are used with or without non-opioid analgesics
  • Step three: Strong opioids are used with or without non-opioid analgesics, and are useful for moderate-to-severe pain

Neuropathic Pain Management

  • Antidepressants that target 5-HT receptors are used
  • Anticonvulsants, such as carbamazepine, are used to target NaCh and GABA receptors
  • Gabapentin and pregabalin, which target GABA receptors, are used
  • Ketamine, which targets NMDA receptors, is used

Pain Management Steps

  • Step one: Non-opioid analgesics are used, including aspirin, paracetamol, and non-steroidal anti-inflammatory drugs (NSAIDs)
  • Step two: Mild opioids, such as codeine, are used with or without non-opioid analgesics
  • Step three: Strong opioids are used with or without non-opioid analgesics, and are useful for moderate-to-severe pain

Neuropathic Pain Management

  • Antidepressants that target 5-HT receptors are used
  • Anticonvulsants, such as carbamazepine, are used to target NaCh and GABA receptors
  • Gabapentin and pregabalin, which target GABA receptors, are used
  • Ketamine, which targets NMDA receptors, is used

Pain Management Steps

  • Step one: Non-opioid analgesics are used, including aspirin, paracetamol, and non-steroidal anti-inflammatory drugs (NSAIDs)
  • Step two: Mild opioids, such as codeine, are used with or without non-opioid analgesics
  • Step three: Strong opioids are used with or without non-opioid analgesics, and are useful for moderate-to-severe pain

Neuropathic Pain Management

  • Antidepressants that target 5-HT receptors are used
  • Anticonvulsants, such as carbamazepine, are used to target NaCh and GABA receptors
  • Gabapentin and pregabalin, which target GABA receptors, are used
  • Ketamine, which targets NMDA receptors, is used

This quiz covers the step-by-step approach to pain management, including non-opioid analgesics, mild opioids, and strong opioids, as well as pharmacological treatments for neuropathic pain.

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