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Pharmacology of Heart Failure

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Questions and Answers

What is the effect of fenoldopam on arteriolar vessels?

Increased permeability

Vasoconstriction

No effect

Vasodilation (correct)

What is a characteristic of calcium channel blockers?

They are moderately efficacious and orally active (correct)

They increase cardiac output in most patients

他們 are effective only for mild hypertension

They are poorly tolerated and produce many compensatory responses

What is the duration of action of fenoldopam?

1 hour

1 day

10 minutes (correct)

30 minutes

What is the mechanism of action of fenoldopam?

Dopamine D1 receptor activation (A) Signup and view all the answers

What is a characteristic of ACE inhibitors and ARBs?

They are two separate classes of antihypertensive drugs (B) Signup and view all the answers

Why are calcium channel blockers commonly used?

They are well-tolerated and produce fewer compensatory responses (B) Signup and view all the answers

What is the primary indication for using digoxin antibodies?

Poisoning with digoxin or other cardiac glycosides (C) Signup and view all the answers

Which type of diuretic is most useful for immediate reduction of pulmonary congestion and severe edema in acute heart failure?

Furosemide (C) Signup and view all the answers

What is the primary benefit of using angiotensin antagonists in chronic heart failure?

Reduced morbidity and mortality (D) Signup and view all the answers

Which of the following is NOT a type of diuretic?

ACE inhibitor (D) Signup and view all the answers

What is the primary benefit of using spironolactone and eplerenone in chronic heart failure?

Reduced morbidity and mortality (B) Signup and view all the answers

What is the first-line therapy for both systolic and diastolic heart failure?

Diuretics (B) Signup and view all the answers

What is a common side effect of verapamil?

Constipation (C) Signup and view all the answers

Which of the following medications is associated with a lupus-like syndrome?

Hydralazine (B) Signup and view all the answers

Which of the following effects is a compensatory response to prazosin?

Increase in cardiac output (C) Signup and view all the answers

Which of the following antihypertensive drugs is likely to cause hyperkalemia?

Aliskiren (A) Signup and view all the answers

Which of the following is a common effect of beta blockers and calcium channel blockers?

Bradycardia and increased PR interval (D) Signup and view all the answers

What is a common effect of thiazide diuretics?

Mild hyperglycemia, hyperuricemia, and hyperlipidemia (A) Signup and view all the answers