63 Questions
What is the primary mechanism of action of glucocorticoid drugs in reducing inflammation?
Inhibiting the activity of phospholipase A2
What is the main physiological action of cortisol?
Modulating the immune response
What is the primary reason for administering glucocorticoid supplementation prior to dental procedures?
To prevent adrenal crisis
What is the half-life of short-acting glucocorticoid drugs?
8-12 hours
What is the hormone that stimulates cortisol release from the adrenal gland?
Adrenocorticotropic hormone (ACTH)
What is the most potent glucocorticoid drug?
Dexamethasone
What is the primary cause of primary adrenal insufficiency?
Autoimmune destruction of the adrenal gland
What is the ideal glucocorticoid dosing?
The lowest dose necessary to achieve therapeutic effect
When is cortisol release typically the highest?
In the morning
What is the purpose of glucocorticoid supplementation in minor dental procedures?
To prevent adrenal crisis
What is a side effect of long-term glucocorticoid use?
All of the above
What is the difference between primary and secondary adrenal insufficiency?
Primary adrenal insufficiency is caused by an adrenal gland problem, while secondary adrenal insufficiency is caused by a pituitary gland problem
What is the effect of cortisol on blood pressure?
It increases blood pressure
What is the function of cortisol in the body?
To regulate blood sugar levels
What is the mechanism of action of glucocorticoid drugs in reducing inflammation?
By inhibiting the production of inflammatory mediators
What is the purpose of preoperative management for dental patients taking corticosteroids?
To provide supplemental corticosteroids
What is the effect of glucocorticoid drugs on the immune system?
They suppress the immune system
What is the most common adverse effect of glucocorticoid drugs?
Immunosuppression
What is the primary indication for glucocorticoid therapy in dental patients?
To reduce inflammation and swelling
What is the effect of cortisol on blood pressure?
It increases blood pressure
What is the primary difference between primary and secondary adrenal insufficiency?
Secondary adrenal insufficiency is caused by pituitary gland dysfunction
What is the purpose of glucocorticoid supplementation in moderate and major dental procedures?
To prevent adrenal crisis
What is the effect of cortisol on the immune system?
It suppresses the immune system
What is the primary cause of adrenal insufficiency?
Adrenal gland dysfunction
What is the purpose of preoperative management for dental patients taking corticosteroids?
To prevent adrenal crisis
What is the effect of long-term glucocorticoid use?
It leads to osteoporosis
What is the half-life of intermediate-acting glucocorticoid drugs?
4-12 hours
For what dental procedures is glucocorticoid supplementation typically required?
Moderate and major dental procedures
What is the primary effect of cortisol on blood pressure?
Increases blood pressure
What is the primary cause of secondary adrenal insufficiency?
Pituitary gland dysfunction
What is the primary action of cortisol on the immune system?
Suppresses the immune response
What is the purpose of preoperative management for dental patients taking corticosteroids?
To reduce the risk of adrenal crisis
What is the primary indication for glucocorticoid therapy in dental patients?
To reduce inflammation
What is the primary effect of long-term glucocorticoid use?
All of the above
What is the primary difference between primary and secondary adrenal insufficiency?
The cause of the adrenal insufficiency
What is the purpose of glucocorticoid supplementation in moderate and major dental procedures?
To prevent adrenal crisis
What is the primary benefit of glucocorticoid supplementation in dental procedures?
Minimizing inflammation and swelling
What is the primary characteristic of short-acting glucocorticoid drugs?
Short duration of action
What is the primary cause of adrenal insufficiency in patients taking corticosteroids?
Sudden cessation of corticosteroid therapy
What is the primary effect of cortisol on blood pressure?
It increases blood pressure
What is the primary indication for glucocorticoid therapy in dental patients?
Reduction of inflammation and swelling
What is the primary difference between primary and secondary adrenal insufficiency?
Primary is caused by adrenal gland dysfunction, while secondary is caused by pituitary gland dysfunction
What is the primary action of cortisol on the immune system?
Suppression of the immune response
What is the primary reason for preoperative management of dental patients taking corticosteroids?
To prevent adrenal insufficiency
What is the primary benefit of glucocorticoid supplementation in moderate and major dental procedures?
Minimizing inflammation and promoting healing
What is the primary goal of glucocorticoid supplementation in dental procedures?
To reduce inflammation
What is the primary difference between primary and secondary adrenal insufficiency?
Primary is caused by adrenal gland damage, while secondary is caused by pituitary gland damage
What is the primary action of cortisol on the immune system?
It suppresses the immune response
What is the primary indication for glucocorticoid therapy in dental patients?
To treat inflammatory conditions
What is the primary effect of long-term glucocorticoid use?
It suppresses the immune response
What is the primary benefit of preoperative management for dental patients taking corticosteroids?
It prevents adrenal insufficiency
What is the primary characteristic of short-acting glucocorticoid drugs?
They have a short half-life
What is the primary cause of adrenal insufficiency in patients taking corticosteroids?
Suppression of the hypothalamic-pituitary-adrenal axis
What is the primary benefit of glucocorticoid supplementation in moderate and major dental procedures?
It prevents adrenal insufficiency
What is the primary hormonal stimulus for cortisol release from the adrenal gland?
Adrenocorticotropin hormone (ACTH)
What is the primary mechanism by which cortisol exerts its anti-inflammatory effects?
Inhibiting the production of inflammatory cytokines
What is the primary indication for glucocorticoid therapy in dental patients?
To reduce inflammation and swelling
What is the primary characteristic of short-acting glucocorticoid drugs?
Short duration of action
What is the primary cause of adrenal insufficiency in patients taking corticosteroids?
Suppressed adrenal function
What is the primary effect of cortisol on blood pressure?
Increases blood pressure
What is the primary goal of glucocorticoid supplementation in dental procedures?
To reduce inflammation and swelling
What is the primary difference between primary and secondary adrenal insufficiency?
Primary involves the adrenal gland, while secondary involves the pituitary gland
What is the primary benefit of glucocorticoid supplementation in moderate and major dental procedures?
Reduces inflammation and swelling
This quiz covers the use of glucocorticoid drugs in dental conditions, their mechanisms of action, and adverse effects. It also explores the physiological actions of cortisol and supplementation requirements for various dental procedures.
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