Pharmacology of Blood Lipids
30 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which lipoprotein is the main carrier of cholesterol?

  • IDL
  • VLDL
  • LDL (correct)
  • Chylomicrons
  • What is the function of lipoprotein lipase (LPL)?

  • Transporting cholesterol to the liver
  • Facilitating cholesterol uptake by cells
  • Hydrolyzing triglycerides (correct)
  • Synthesizing lipoproteins
  • Which lipoprotein is responsible for the reverse transport of cholesterol to the liver?

  • HDL (correct)
  • VLDL
  • IDL
  • LDL
  • What is the most frequent cause of hyperlipidemia?

    <p>Dietary excess</p> Signup and view all the answers

    Which type of hyperlipidemia is characterized by elevated triglycerides and cholesterol?

    <p>Type IIb</p> Signup and view all the answers

    What is the function of bile acids in the body?

    <p>Modulating cholesterol levels</p> Signup and view all the answers

    Which lipoprotein is responsible for transporting triglycerides to adipose tissue, heart, and skeletal muscle?

    <p>VLDL</p> Signup and view all the answers

    What is the main component of the core of lipoproteins?

    <p>Triglycerides</p> Signup and view all the answers

    Which lipoprotein is synthesized in the intestine?

    <p>Chylomicrons</p> Signup and view all the answers

    Which lipoprotein is responsible for cholesterol uptake by cells?

    <p>LDL</p> Signup and view all the answers

    Which enzyme catalyzes the rate limiting step of hepatic cholesterol synthesis?

    <p>HMG-CoA reductase</p> Signup and view all the answers

    What is the main content of LDL (low-density lipoprotein)?

    <p>Cholesterol esters</p> Signup and view all the answers

    Which lipoprotein carries the apolipoprotein B-100 and binds to receptors of target organs for cholesterol uptake?

    <p>LDL</p> Signup and view all the answers

    What is the density range of VLDL (very low-density lipoprotein)?

    <p>0.950-1.006 g/mL</p> Signup and view all the answers

    Which lipoprotein originates from the liver?

    <p>VLDL</p> Signup and view all the answers

    What is the main function of triglycerides (TGs)?

    <p>Storing energy</p> Signup and view all the answers

    Which class of drugs is used to lower triglyceride and/or cholesterol blood levels?

    <p>Hypolipidemic drugs</p> Signup and view all the answers

    What is the main building block of biological membranes and steroid hormones?

    <p>Cholesterol</p> Signup and view all the answers

    Which lipoprotein transports cholesterol from tissue cells back to the liver?

    <p>HDL</p> Signup and view all the answers

    What is the rate limiting step of hepatic cholesterol synthesis?

    <p>HMG-CoA reductase</p> Signup and view all the answers

    Which of the following drugs inhibits the Niemann-Pick C1-Like1 (NPC1L1) cholesterol transporter?

    <p>Ezetimibe</p> Signup and view all the answers

    What is the maximal effect of bile acid sequestering resins drugs on blood LDL cholesterol?

    <p>20% reduction</p> Signup and view all the answers

    Which adverse effect is associated with cholestyramine use?

    <p>Bloating</p> Signup and view all the answers

    Which drug is used as an adjunct to diet to reduce triglyceride levels in adults with severe hypertriglyceridemia?

    <p>Icosapent ethyl</p> Signup and view all the answers

    Which class of drugs has the greatest reduction in LDL cholesterol?

    <p>HMG-CoA reductase inhibitors</p> Signup and view all the answers

    Which adverse effect is associated with HMG-CoA reductase inhibitors?

    <p>Rhabdomyolysis</p> Signup and view all the answers

    Which drug can be used as monotherapy if statins are not tolerated?

    <p>Ezetimibe</p> Signup and view all the answers

    Which drug can be combined with ezetimibe to lower LDL cholesterol even more?

    <p>HMG-CoA reductase inhibitors</p> Signup and view all the answers

    Which drug has the main effect of reducing hepatic production of triglyceride-rich VLDL?

    <p>Icosapent ethyl</p> Signup and view all the answers

    Which drug is used as an adjunct to maximally tolerated statin therapy in adult patients with TG levels >150 mg/dL and two or more risk factors for cardiovascular disease?

    <p>Icosapent ethyl</p> Signup and view all the answers

    More Like This

    Pharmacology of Blood Lipids
    33 questions
    Pharmacology of Blood Pressure Regulation
    18 questions
    Pharmacology & Blood Transfusion Basics
    31 questions
    Use Quizgecko on...
    Browser
    Browser