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Questions and Answers
What happens to highly lipid soluble barbiturates and benzodiazepines after they are distributed into the body?
What happens to highly lipid soluble barbiturates and benzodiazepines after they are distributed into the body?
- They are oxidized into active metabolites
- They are excreted into the kidneys
- Redistribution to peripheral tissue occurs (correct)
- They are secreted into milk
What is the mechanism of action of Barbiturates?
What is the mechanism of action of Barbiturates?
- By increasing the acetylcholine levels in the brain
- By blocking the GABA receptor activity
- By decreasing the dopamine levels in the brain
- By enhancing the GABA receptor activity (correct)
What is the mechanism of action of barbiturates and benzodiazepines?
What is the mechanism of action of barbiturates and benzodiazepines?
- They have an allosteric effect that facilitates the GABA action (correct)
- They block the chloride ions conductance
- They have a direct effect on GABA receptors
- They inhibit the GABA inhibitory effect
How are barbiturates and benzodiazepines excreted from the body?
How are barbiturates and benzodiazepines excreted from the body?
How do Benzodiazepines differ from Barbiturates in terms of their chemistry?
How do Benzodiazepines differ from Barbiturates in terms of their chemistry?
What happens to barbiturates in the liver?
What happens to barbiturates in the liver?
What is the duration of action of Ultrashort Acting Barbiturates?
What is the duration of action of Ultrashort Acting Barbiturates?
What is the general anesthetic effect of Sedative-Hypnotics?
What is the general anesthetic effect of Sedative-Hypnotics?
How are barbiturates and benzodiazepines absorbed into the body?
How are barbiturates and benzodiazepines absorbed into the body?
What is the effect of phenobarbitone on microsomal enzymes?
What is the effect of phenobarbitone on microsomal enzymes?
Which of the following is an Intermediate Acting Benzodiazepine?
Which of the following is an Intermediate Acting Benzodiazepine?
What is the onset of action of Remimazolam?
What is the onset of action of Remimazolam?
What is the consequence of the body adapting to the continued presence of Barbiturates and Benzodiazepines due to decreased sensitivity of GABA receptors?
What is the consequence of the body adapting to the continued presence of Barbiturates and Benzodiazepines due to decreased sensitivity of GABA receptors?
What is the consequence of suddenly stopping or reducing the dosage of Barbiturates and Benzodiazepines?
What is the consequence of suddenly stopping or reducing the dosage of Barbiturates and Benzodiazepines?
What is the contraindication for Barbiturates and Benzodiazepines in patients with acute narrow angle glaucoma?
What is the contraindication for Barbiturates and Benzodiazepines in patients with acute narrow angle glaucoma?
What is the specific antagonist for Benzodiazepines overdose?
What is the specific antagonist for Benzodiazepines overdose?
What is the mechanism of action of Flumazenil?
What is the mechanism of action of Flumazenil?
What is the characteristic of Flumazenil's molecular structure?
What is the characteristic of Flumazenil's molecular structure?
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