Pharmacology of Adrenergic Agonists Part 1

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Which neurotransmitter is associated with the parasympathetic nervous system?

Acetylcholine (ACh) (correct)

Noradrenaline

Dopamine

Adrenaline

Which drug is classified as a catecholamine adrenergic agonist?

Cocaine

Ephedrine

Salbutamol

Dobutamine (correct)

What is the direct mode of action of adrenaline?

Inhibition of catecholamine reuptake

Indirectly stimulate cholinergic receptors

Release of catecholamines from nerve endings

Stimulation of adrenoceptors (correct)

Which adrenergic agonist has both direct and indirect modes of action?

Ephedrine Signup and view all the answers

Which receptor type is stimulated by low concentration of adrenaline?

β1,2,3 adrenoceptors Signup and view all the answers

Why is adrenaline ineffective when taken orally?

It is rapidly destroyed by MAO & COMT enzymes. Signup and view all the answers

What is the main function of the Autonomic Nervous System (ANS)?

Organizes the function of involuntary organs Signup and view all the answers

Which neurotransmitters are associated with the sympathetic nervous system?

Norepinephrine (NE) and Adrenaline (Epinephrine) Signup and view all the answers

What are the two main types of adrenoceptors in the body?

α and β adrenoceptors Signup and view all the answers

Which ILO (Intended Learning Outcome) relates to explaining information related to direct-acting adrenoceptor agonists?

ILO 2 Signup and view all the answers

What do adrenergic agonists act on in the body?

Involuntary organs Signup and view all the answers

Which classification is based on the receptor selectivity of adrenergic agonists?

Selective and Non-selective agonists Signup and view all the answers

Which receptor stimulation increases blood pressure?

Stimulation of α1 receptors Signup and view all the answers

What is the effect of stimulating α1 receptors on blood pressure?

Increases blood pressure Signup and view all the answers

Which receptor stimulation causes norepinephrine release?

α2 receptors Signup and view all the answers

What is the effect of stimulating β2 receptors on heart rate?

Increases heart rate (tachycardia) Signup and view all the answers

Which receptor stimulation causes bronchoconstriction?

α1 receptors Signup and view all the answers

What is the predominant receptor type stimulated by Isoproterenol (Isoprenaline)?

β1 receptors Signup and view all the answers