Recent Lessons

Show all results for ""

Feature Overview

Ace your exams with our all-in-one platform for creating and sharing quizzes and tests.

Quizzes

Create quizzes and tests automatically from your content using AI.

Flashcards

Automatically turn your notes into digital flashcards.

Share, Export & Embed

Share with classmates or export to Excel and your learning management system.

Stats & Reporting

Auto-grading quizzes and tests with detailed stats and reports.

Mobile Apps

The smarter way to study – wherever you are.

Pricing

Search...

10 Questions

0 Views

Pharmacology Lecture 13+14 Antibiotics

Choose a study mode

Play Quiz

Study Flashcards

Spaced Repetition

Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is the primary mechanism of resistance to penicillins and other β-lactam antibiotics?

Inactivation of the antibiotic by β-lactamase (correct)

Antibiotic efflux

Impaired penetration of the drug to the target PBPs

Modification of target penicillin-binding proteins (PBPs)

Which of the following is a key characteristic of the mechanism of action of penicillins?

They are effective against both rapidly growing and slow-growing organisms

They are active against mycobacteria and viruses

They interfere with bacterial cell wall synthesis by inhibiting transpeptidation or cross-linkage (correct)

They are bacteriostatic and work in a concentration-dependent fashion

Which class of penicillins is resistant to staphylococcal β-lactamases?

Extended-spectrum penicillins

Antistaphylococcal penicillins (correct)

Antipseudomonal penicillins

Aminopenicillins

What is the primary difference between penicillins and extended-spectrum penicillins?

Extended-spectrum penicillins are more susceptible to hydrolysis by β-lactamases Signup and view all the answers

Which of the following is true about the bactericidal activity of penicillins?

They are concentration-dependent and work in a time-dependent fashion Signup and view all the answers

Which of the following β-lactam antibiotics has improved activity against Gram-negative rods compared to penicillin?

Aminopenicillins Signup and view all the answers

How do penicillins exert their bactericidal effect?

By interfering with the last step of bacterial cell wall synthesis Signup and view all the answers

Which of the following is a key characteristic of antistaphylococcal penicillins?

They are active against anaerobic bacteria Signup and view all the answers

What is the primary reason why penicillins are inactive against organisms devoid of a peptidoglycan cell wall?

Penicillins target the peptidoglycan synthesis pathway Signup and view all the answers

Which of the following is a common mechanism of resistance to penicillins and other β-lactam antibiotics?

All of the above Signup and view all the answers