10 Questions
Which of the following is the primary mechanism of resistance to penicillins and other β-lactam antibiotics?
Inactivation of the antibiotic by β-lactamase
Which of the following is a key characteristic of the mechanism of action of penicillins?
They interfere with bacterial cell wall synthesis by inhibiting transpeptidation or cross-linkage
Which class of penicillins is resistant to staphylococcal β-lactamases?
Antistaphylococcal penicillins
What is the primary difference between penicillins and extended-spectrum penicillins?
Extended-spectrum penicillins are more susceptible to hydrolysis by β-lactamases
Which of the following is true about the bactericidal activity of penicillins?
They are concentration-dependent and work in a time-dependent fashion
Which of the following β-lactam antibiotics has improved activity against Gram-negative rods compared to penicillin?
Aminopenicillins
How do penicillins exert their bactericidal effect?
By interfering with the last step of bacterial cell wall synthesis
Which of the following is a key characteristic of antistaphylococcal penicillins?
They are active against anaerobic bacteria
What is the primary reason why penicillins are inactive against organisms devoid of a peptidoglycan cell wall?
Penicillins target the peptidoglycan synthesis pathway
Which of the following is a common mechanism of resistance to penicillins and other β-lactam antibiotics?
All of the above
Test your knowledge on antibiotics and their mechanisms of action, focusing on β-lactam antibiotics, vancomycin, and daptomycin. This quiz covers the pharmacology of penicillins and related antibiotics.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
