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Pharmacology II: Antidepressant Drugs

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15 Questions

What is the primary mechanism by which antidepressants exert their therapeutic effect?

Preventing the reuptake of dopamine, norepinephrine, and serotonin by presynaptic neurons

Which of the following antidepressants is classified as a Mood-Stabilizing Agent?

Lithium carbonate

What is a common side effect of tricyclic antidepressants?

Sedation

Which of the following conditions is NOT a listed use of antidepressant drugs?

Hypertension

What is the action of tricyclic antidepressants on acetylcholine?

They block the action of acetylcholine

What is the primary use of lithium carbonate in treating bipolar disorder?

To treat and prevent manic episodes

Why are baseline studies of renal, cardiac, and thyroid status necessary before starting lithium therapy?

Because adverse drug effects involve these organ systems

What should the patient be advised to do if they experience dry mouth while taking lithium carbonate?

Rinse their mouth frequently and practice good oral hygiene

What should the patient be cautioned to avoid when taking lithium carbonate?

Driving and other activities requiring alertness

Why should patients receiving MAO inhibitors avoid certain foods and beverages?

Because they contain tyramine

What is the primary way that tricyclic antidepressants alleviate depression?

By restoring the balance of neurotransmitters in the brain

What is a common adverse effect of Selective Serotonin Reuptake Inhibitors (SSRIs)?

Gastrointestinal symptoms

Why are Monoamine Oxidase Inhibitors (MAOIs) infrequently used?

They may interact with certain foods and drugs to produce severe hypertension

What is the result of tyramine absorption when deactivation is blocked by MAOIs?

A sudden release of large amounts of norepinephrine

What type of food should be avoided when taking MAOIs?

Aged cheeses and meats

This quiz covers the introduction to antidepressant drugs, including the imbalance of neurotransmitters in patients with depression, and the two groups of antidepressant drugs: Tricyclic Antidepressants and Selective Serotonin Reuptake Inhibitors.

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