Drug Therapy for Tuberculosis

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Questions and Answers

Which of the following is the primary rationale for using multiple drugs in the treatment of tuberculosis?

  • To reduce the risk of adverse drug effects by using lower doses of each drug.
  • To increase patient adherence by simplifying the drug regimen.
  • To target different stages of Mycobacterium tuberculosis growth and prevent the development of drug resistance. (correct)
  • To enhance the absorption and distribution of each individual drug.

A patient is diagnosed with latent tuberculosis. Which statement best describes this condition?

  • The patient requires immediate hospitalization due to the severity of the infection.
  • The patient has active symptoms of tuberculosis and is highly contagious.
  • The patient has a positive TB skin test or blood test but no active symptoms and is not contagious. (correct)
  • The patient has developed resistance to multiple first-line antitubercular drugs.

Which of the following is a common adverse effect associated with isoniazid (INH), a first-line antitubercular drug?

  • Nephrotoxicity causing kidney damage.
  • Peripheral neuropathy leading to numbness and tingling in the extremities. (correct)
  • Ototoxicity resulting in hearing loss.
  • Hyperglycemia causing elevated blood sugar levels.

Which of the following is an important nursing consideration when administering rifampin to a patient?

<p>Monitor liver function tests regularly due to the risk of hepatotoxicity. (D)</p> Signup and view all the answers

Which strategy is MOST effective in promoting adherence to long-term antitubercular drug therapy?

<p>Implementing directly observed therapy (DOT) where a healthcare worker watches the patient take each dose. (A)</p> Signup and view all the answers

Flashcards

Tuberculosis (TB)

An infection caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs, but can spread to other organs.

Latent TB

A form of TB where the bacteria are present in the body but not causing symptoms. The immune system keeps the infection under control, but it can become active later.

Active TB

A form of TB where the bacteria are actively multiplying and causing symptoms such as coughing, fever, and weight loss.

Drug-resistant TB

TB that is resistant to one or more first-line anti-TB drugs.

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First-line anti-TB drugs

A group of drugs used to treat TB that are typically prescribed first.

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Study Notes

Drug Therapy for Tuberculosis and Mycobacterium avium Complex

  • After studying this chapter, students should be able to describe the characteristics of tuberculosis and Mycobacterium avium complex, latent, active, and drug-resistant tuberculosis.
  • They should also understand drug therapy for tuberculosis, including the rationale for multiple-drug therapy.
  • Students should be able to list the action, uses, adverse effects, contraindications, and nursing implications of first-line antitubercular drugs.
  • Students need to describe how second-line antitubercular drugs are added to drug regimens for multidrug-resistant tuberculosis.
  • Students should describe the drugs used for preventing or treating Mycobacterium avium complex.
  • The ways to increase adherence to antitubercular drug therapy should be discussed.
  • The nursing process in the care of patients undergoing drug therapy for tuberculosis should also be covered.

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