Pharmacology Exam Preparation
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Questions and Answers

Which of the following are considered as toxic effect of Procainamide?

  • Tachycardia (correct)
  • Bradycardia (correct)
  • Raynaud's Type Arterial Insufficiency (correct)
  • Pharyngitis (correct)
  • Which of the following are examples of drug metabolism?

  • Conversion of hydrophobic drug to a hydrophilic drug (correct)
  • Conversion of a prodrug to the active form of the drug (correct)
  • Conversion of a toxic component of a drug to a non-toxic form (correct)
  • Conversion of active drugs to inactive drugs (correct)
  • Which of the following statements is/are incorrect?

  • Class IV cardioactive drugs are calcium channel blockers.
  • Class I cardioactive drugs are rapid potassium channel blockers. (correct)
  • Example of a class II cardioactive drug is Xylocaine. (correct)
  • Study Notes

    Instructions for Exam

    • Read questions carefully and choose best answer
    • Avoid erasures/superimposition
    • Use black ballpoint pen only.
    • Incorrect use of format penalizes.

    1. Exam Focus

    • Analysis, assessment, and evaluation of circulating concentrations of drugs.

    2. Drug Testing

    • It involves the (biochemical pathway responsible for metabolism for drugs)
    • Drug testing is a testing method, including Toxicology
    • MFO system, MFA System, CYP 450, CYP 2D6, are all parts of drug testing/metabolism

    3. Pharmacodynamics

    • Describes the relationship between drug concentration at the target site and the response of the tissues

    4. Pharmacogenomics

    • Studies genes that affect performance of a drug in an individual
    • Includes pharmacogenomics and pharmacokinetics.

    5. Pharmacokinetics

    • Describes the relationship between drug dose and blood levels
    • Explains the pharmacodynamics of drugs.
    • Includes drug absorption, distribution, and metabolism.

    6. Therapeutic Range

    • Fraction of drug reaching the blood/plasma
    • Includes the Minimum effective concentration (MEC) and Maximum safe concentration (MSC)

    7. Drug Absorption

    • Often involves reactions like oxidation or reduction
    • Includes passive diffusion, and other absorption methods

    8. Drug Metabolism Processes

    • Includes conversion of active drugs to inactive form,
    • conversion of prodrug to an active form, converts a hydrophobic drug into a hydrophilic drug, and converts a drug to a nontoxic form.

    9. Cardioactive Drug Classification

    • Quinidine and Lidocaine are cardioactive drugs.
    • Quinidine is not a rapid sodium channel blocker.
    • Lidocaine is a rapid sodium channel blocker.

    10. Class IV Cardiac Drugs (Incorrect statements)

    • Class IV is incorrect
    • Example of a class II cardiac drug is Xylocaine or Xylocaine
    • Class I cardiac drugs are rapid potassium channel blockers.

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    Description

    Prepare for your pharmacology exam with this comprehensive quiz covering drug testing, pharmacodynamics, pharmacogenomics, and pharmacokinetics. Each question assesses your understanding of crucial concepts in drug metabolism and therapy. Sharpen your knowledge to excel in your pharmacology assessments.

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