Pharmacology Drug Classes Flashcards
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Questions and Answers

What do adrenergic agents do?

  • Suppress seizures
  • Induce sedation
  • Inhibit parasympathetic impulses
  • Stimulate the sympathetic nervous system (correct)
  • Which term is synonymous with adrenergic agents?

  • Anticholinergics
  • Cholinergic agents
  • Sympatholytics
  • Sympathomimetics (correct)
  • What is the function of the alpha-1 receptor?

    Treatment of nasal congestion or hypotension; causes mydriasis during ophthalmic examinations.

    What is the role of the alpha-2 receptor?

    <p>Treatment of hypertension; reduces the release of norepinephrine.</p> Signup and view all the answers

    What is beta-1 receptor used for?

    <p>Treatment of cardiac arrest, heart failure, and shock.</p> Signup and view all the answers

    What medical conditions are treated by beta-2 receptors?

    <p>Asthma and premature labor contractions.</p> Signup and view all the answers

    What do adrenergic antagonists do?

    <p>Block adrenergic receptors, specific to either alpha or beta blockade.</p> Signup and view all the answers

    What do cholinergic agents mimic?

    <p>Parasympathetic nervous system</p> Signup and view all the answers

    What do cholinergic-blocking agents inhibit?

    <p>Parasympathetic impulses.</p> Signup and view all the answers

    How do benzodiazepines function?

    <p>By binding to the GABA receptor-chloride channel molecule.</p> Signup and view all the answers

    What is the effect of barbiturates?

    <p>Intensify the effect of GABA throughout the brain.</p> Signup and view all the answers

    What is the goal of anti-seizure pharmacology?

    <p>To suppress neuronal activity enough to prevent abnormal or repetitive firing.</p> Signup and view all the answers

    What does GABA stand for?

    <p>Gamma-aminobutyric acid.</p> Signup and view all the answers

    What is Phenobarbital's unique ability?

    <p>To suppress abnormal neuronal discharges without causing sedation.</p> Signup and view all the answers

    What do hydantoin and phenytoin-like drugs desensitize?

    <p>Sodium channels.</p> Signup and view all the answers

    What do succinimides do?

    <p>Suppress seizures by delaying calcium influx into neurons.</p> Signup and view all the answers

    What is the mechanism of action for tricyclic antidepressants?

    <p>Inhibiting the presynaptic reuptake of both norepinephrine and serotonin.</p> Signup and view all the answers

    What do selective serotonin reuptake inhibitors (SSRIs) do?

    <p>Slow the reuptake of serotonin into presynaptic nerve terminals.</p> Signup and view all the answers

    What do serotonin-norepinephrine reuptake inhibitors (SNRIs) inhibit?

    <p>The reabsorption of serotonin and norepinephrine.</p> Signup and view all the answers

    What do monoamine oxidase inhibitors (MAOIs) inhibit?

    <p>Monoamine oxidase.</p> Signup and view all the answers

    What is the function of glutamate inhibitors/serotonin receptor antagonists?

    <p>To alter ionic activity and influence the release, synthesis, and reuptake of various neurotransmitters.</p> Signup and view all the answers

    What do CNS stimulants do?

    <p>Stimulate specific areas of the CNS to heighten alertness and increase focus.</p> Signup and view all the answers

    What do phenothiazines do?

    <p>Prevent dopamine and serotonin from occupying critical neurologic receptor sites.</p> Signup and view all the answers

    What is the action of nonphenothiazines?

    <p>Blocking postsynaptic D2 dopamine receptors.</p> Signup and view all the answers

    What do atypical antipsychotics block?

    <p>D2 receptors and serotonin (5-HT) and alpha-adrenergic receptors.</p> Signup and view all the answers

    What do opioid agonists do?

    <p>Bind to opioid receptors and produce multiple responses.</p> Signup and view all the answers

    What do opioid antagonists compete with?

    <p>Opioids for access to opioid sites.</p> Signup and view all the answers

    What do NSAIDs inhibit?

    <p>Cyclooxygenase, an enzyme responsible for the formation of prostaglandins.</p> Signup and view all the answers

    What are triptans/ergot alkaloids thought to do?

    <p>Act by constricting certain intracranial vessels.</p> Signup and view all the answers

    What do esters/amides block?

    <p>Neuronal pain impulses.</p> Signup and view all the answers

    What do inhalation gaseous agents produce?

    <p>Analgesia caused by suppression of pain mechanisms in the CNS.</p> Signup and view all the answers

    What is the function of a depolarizing blocker?

    <p>Works by causing muscle paralysis by preventing muscle fiber contraction.</p> Signup and view all the answers

    Study Notes

    • Adrenergic Agents: Stimulate the sympathetic nervous system, inducing fight-or-flight response symptoms.
    • Sympathomimetics: Another term for Adrenergic Agents, highlighting their ability to mimic sympathetic nervous system actions.
    • Alpha-1 Receptor: Used for treating nasal congestion and hypotension, causing mydriasis (pupil dilation) during eye exams.
    • Alpha-2 Receptor: Primarily used for hypertension treatment; reduces norepinephrine release, lowering blood pressure.
    • Beta-1 Receptor: Critical in treating cardiac arrest, heart failure (HF), and shock.
    • Beta-2 Receptors: Effective in managing asthma symptoms and preventing premature labor contractions.
    • Adrenergic Antagonists: Block adrenergic receptors, with the capability to target either alpha or beta receptors.

    Cholinergic Agents and Blockers

    • Cholinergic Agents: Mimic parasympathetic nervous system actions, promoting rest-and-digest responses.
    • Parasympathomimetics: Another name for Cholinergic Agents, reflecting their similar functions.
    • Cholinergic-Blocking Agents: Inhibit parasympathetic impulses and suppress the fight-or-flight response.
    • Anticholinergics: The class of drugs that includes Cholinergic-Blocking Agents.

    Anxiolytics and Anticonvulsants

    • Benzodiazepines: Bind to GABA receptor-chloride channel complex, promoting calmness and sedation.
    • Barbiturates: Intensify GABA's effects across the brain by binding to the GABA receptor-chloride channel.
    • Anxiety and Insomnia Treatment: Mechanism believed linked to D2 dopamine receptors and serotonin receptor activities.
    • Anti-seizure Pharmacology: Aims to suppress neuronal activity to prevent abnormal firing.
    • GABA: The primary inhibitory neurotransmitter in the brain.
    • Phenobarbital: Allows the suppression of abnormal neuronal discharges without sedation.

    Seizure Medications

    • Hydantoin and Phenytoin-Like Drugs: Desensitize sodium channels, delaying neuron depolarization.
    • Succinimides: Suppress seizures by delaying calcium influx into neurons.

    Antidepressants

    • Tricyclic Antidepressants: Inhibit the reuptake of norepinephrine and serotonin at presynaptic neurons.
    • Selective Serotonin Reuptake Inhibitors (SSRIs): Slow the reuptake of serotonin into presynaptic nerve terminals, enhancing mood.
    • Serotonin-norepinephrine Reuptake Inhibitors (SNRIs): Raise serotonin and norepinephrine levels, improving mood.
    • Monoamine Oxidase Inhibitors (MAOIs): Prevent monoamine oxidase from terminating neurotransmitter actions.

    CNS Stimulants and Antipsychotics

    • Glutamate Inhibitor / Serotonin Receptor Antagonist: Alters neuronal ionic activity and impacts neurotransmitter release and uptake.
    • CNS Stimulants: Heighten alertness and increase focus by stimulating specific CNS areas.
    • Phenothiazines: Prevent dopamine and serotonin from occupying essential receptor sites in neurologic pathways.
    • NonPhenothiazines: Block postsynaptic D2 dopamine receptors for antipsychotic effects.
    • Atypical Antipsychotics: Block both D2 and serotonin (5-HT) receptors alongside alpha-adrenergic receptors.

    Pain Management and Opioids

    • Opioid Agonists: Bind to opioid receptors, resulting in various biological responses.
    • Opioid Antagonists: Compete with opioids for receptor sites, blocking their effects.
    • NSAIDs: Inhibit cyclooxygenase, preventing the formation of pain-inducing prostaglandins.
    • Triptans / Ergot Alkaloids: Serotonin agonists thought to constrict specific intracranial blood vessels, relieving migraine pain.
    • Esters / Amides: Block sodium channels, inhibiting neuronal pain impulses.
    • Inhalation Gaseous Agents: Create analgesic effects through interactions with the CNS's pain mechanisms.

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    Test your knowledge on key pharmacological terms with these flashcards focusing on drug classes. Each card presents a word along with its definition, providing a quick way to learn and reinforce your understanding of pharmacology concepts. Perfect for students and professionals alike!

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