Pharmacology: Drug Classes p9🍓
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Questions and Answers

Which of the following drug classes can induce Cushing's syndrome and osteoporosis after long-term administration?

  • Antibiotics
  • Glucocorticoids (correct)
  • Beta-blockers
  • NSAIDs

Which of the following terms is used to describe a drug that blocks the action of epinephrine?

  • Alpha antagonist (correct)
  • Calcium channel blockers
  • Beta agonists
  • Cholinergic agonists

Which of the following drugs could be used for the treatment of wet cough?

  • Mucolytics / expectorant (correct)
  • Codeine
  • Loratadine
  • Dextromethorphan

Which of the following drugs is considered non-sedative?

<p>Cetirizine (B)</p> Signup and view all the answers

Which of the following acts as a uterine stimulant (ecbolic)?

<p>Oxytocin (C), Prostaglandin (D)</p> Signup and view all the answers

Which of the following drugs is an inhibitor of lipoxygenase?

<p>Zileuton (C)</p> Signup and view all the answers

Which of the following drugs activates alpha-adrenergic receptors but not beta-adrenergic receptors?

<p>Noradrenaline (C)</p> Signup and view all the answers

Which of the following drugs activates both alpha and beta-adrenergic receptors?

<p>Adrenaline (C)</p> Signup and view all the answers

Which of the following drugs activates beta-adrenergic receptors only?

<p>Isoproterenol (D)</p> Signup and view all the answers

Which type of antagonist exists between histamine and cyproheptadine?

<p>Pharmacological antagonist (B)</p> Signup and view all the answers

Which of the following is a mast cell stabilizer?

<p>Cromoglycate (A)</p> Signup and view all the answers

Which of the following agents is effective against bronchial asthma and recommended before sleep?

<p>Theophylline (C)</p> Signup and view all the answers

Which of the following induces anti-androgenic activity and androgenic side effects like hyperprolactinemia in men, and is used for the treatment of peptic ulcer?

<p>Ranitidine / Cimetidine (B)</p> Signup and view all the answers

Which agent of the following could block the action of acetylcholine at the muscarinic junction?

<p>Atropine (A)</p> Signup and view all the answers

Which receptor(s) could be activated by adrenaline?

<p>Alpha &amp; Beta (C)</p> Signup and view all the answers

When 100 mg of the drug X was given intravenously, after 8 hours, its blood concentration became 50 mg, and after 16 hours, its concentration became 25. Which of the following is the drug's half-life?

<p>8 hours (C)</p> Signup and view all the answers

Flashcards

Glucocorticoids

A class of drugs that can induce Cushing's syndrome and osteoporosis after long-term administration.

Alpha antagonist

A drug that blocks the action of epinephrine.

Mucolytics / expectorant

Drugs used to treat wet coughs by thinning mucus and making it easier to cough up.

Non-sedative antihistamine

An antihistamine that does not cause drowsiness.

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Oxytocin

A hormone (and drug) that stimulates uterine contractions - helps with childbirth.

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Zileuton

A drug that inhibits lipoxygenase, an enzyme involved in the production of inflammatory mediators.

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Dobutamine

A drug that activates alpha-adrenergic receptors but not beta-adrenergic receptors.

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Adrenaline

A hormone that activates both alpha and beta-adrenergic receptors.

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Isoprenaline

A drug that activates beta-adrenergic receptors only.

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Competitive antagonist

A type of drug that binds to the same receptor as another drug, but does not activate it, thus blocking the action of the other drug.

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Cromoglycate

A mast cell stabilizer that prevents the release of histamine from mast cells.

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Formoterol

A long-acting beta-agonist used for the treatment of asthma.

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Ranitidine / Cimetidine

Drugs that block histamine receptors in the stomach, used for the treatment of peptic ulcers.

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Atropine

A drug that blocks acetylcholine at muscarinic receptors.

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Adrenaline

A hormone that can activate both alpha and beta receptors.

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Half-life of a drug

The time it takes for the concentration of the drug in the blood to reduce by half.

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Study Notes

Drug Classes and Effects

  • Cushing's syndrome and osteoporosis can be induced by long-term use of glucocorticoids.
  • Beta-blockers do not cause Cushing's syndrome or osteoporosis.
  • NSAIDs do not cause Cushing's syndrome or osteoporosis.
  • Antibiotics do not cause Cushing's syndrome or osteoporosis.

Drug Action and Terms

  • A calcium channel blocker blocks the action of epinephrine.
  • A beta agonist enhances epinephrine's effect.
  • A alpha antagonist blocks the action of epinephrine.
  • Cholinergic agonists mimic the actions of acetylcholine.

Drug Uses

  • Mucolytics/expectorants treat wet coughs.
  • Codeine and dextromethorphan can also treat coughs.
  • Loratadine is not a treatment for wet cough.

Drug Properties

  • Diphenhydramine, chlorpheniramine, and promethazine are sedative antihistamines.
  • Cetirizine is a non-sedating antihistamine.

Hormonal Effects

  • Prostaglandins are uterine stimulants.
  • Oxytocin, causes uterine contractions, is also a uterine stimulant.
  • Progesterone and estrogen are not uterine stimulants.

Enzyme Inhibitors

  • Lipoxygenase inhibitors include montelukast, zileuton, aspirin and ibuprofen.

Receptor Activation

  • Adrenaline activates both alpha and beta adrenergic receptors.
  • Noradrenaline primarily activates alpha receptors.
  • Isoproterenol and phenylephrine primarily activate beta receptors.
  • Dobutamine primarily activates beta receptors.

Antagonist Types

  • Histamine and cyproheptadine have a competitive antagonist relationship.

Mast Cell Stabilizer

  • Cromolyn and fluticasone are mast cell stabilizers.

Asthma Treatment

  • Salbutamol and Formoterol treat bronchial asthma.
  • Beclomethasone and theophylline are also used in asthma treatment.

Anti-androgenic Effects

  • Ranitidine and omeprazole are used to treat petic ulcers.
  • Prostaglandins, ibuprofen, and aspirin are not used to treat ulcers.

Acetylcholine Blockers

  • Atropine blocks the action of acetylcholine.

Adrenaline Receptor

  • Adrenaline activates alpha and beta receptors.

Drug Half-Life

  • Drug X has an 8-hour half-life.

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Description

Test your knowledge on various drug classes, their effects, and uses in this pharmacology quiz. Learn about the differences between glucocorticoids, beta-blockers, and more. This quiz covers fundamental drug properties and hormonal effects relevant to healthcare professionals.

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