Podcast
Questions and Answers
What is a primary advantage of the sublingual and buccal routes of drug administration?
What is a primary advantage of the sublingual and buccal routes of drug administration?
- Usually more cost-effective
- Rapid absorption (correct)
- Requires first-pass metabolism
- Limited to large doses
Which of the following is a disadvantage of the pulmonary route for drug administration?
Which of the following is a disadvantage of the pulmonary route for drug administration?
- Difficulties in adjusting correct dose (correct)
- Avoids first-pass metabolism
- Rapid onset of action
- Large surface area for absorption
What is a characteristic disadvantage of the rectal route of drug administration?
What is a characteristic disadvantage of the rectal route of drug administration?
- May cause irritation of mucosa (correct)
- Absorption is quick and reliable
- High concentration can be applied
- Used for patients in stable condition
Which of the following is true regarding the advantages of the sublingual and buccal routes?
Which of the following is true regarding the advantages of the sublingual and buccal routes?
Which statement accurately reflects a challenge associated with the pulmonary route?
Which statement accurately reflects a challenge associated with the pulmonary route?
What is the primary method of absorption for drugs administered via the sublingual route?
What is the primary method of absorption for drugs administered via the sublingual route?
Which condition is best treated by the sublingual route of drug administration?
Which condition is best treated by the sublingual route of drug administration?
What is a characteristic of the buccal route of drug administration?
What is a characteristic of the buccal route of drug administration?
Which of the following describes the common feature of alternate routes for systemic drug administration?
Which of the following describes the common feature of alternate routes for systemic drug administration?
What distinguishes transmucosal drug delivery from transdermal delivery?
What distinguishes transmucosal drug delivery from transdermal delivery?
What defines systemic administration of drugs?
What defines systemic administration of drugs?
Which of the following is not a characteristic of parenteral drug administration?
Which of the following is not a characteristic of parenteral drug administration?
What is first-pass metabolism?
What is first-pass metabolism?
Which administration route allows for rapid onset of drug effects?
Which administration route allows for rapid onset of drug effects?
Which of the following routes is classified as local/site-specific administration?
Which of the following routes is classified as local/site-specific administration?
What is a characteristic of inhalation as a drug delivery method?
What is a characteristic of inhalation as a drug delivery method?
Which method is not categorized under parenteral routes?
Which method is not categorized under parenteral routes?
What type of drug administration would be appropriate for localized effects on injured tissue?
What type of drug administration would be appropriate for localized effects on injured tissue?
Flashcards
Sublingual Drug Administration
Sublingual Drug Administration
Drug placed under the tongue for rapid absorption into the bloodstream.
Buccal Drug Administration
Buccal Drug Administration
Drug placed between cheek and gum for slower, sustained absorption.
Transmucosal drug delivery
Transmucosal drug delivery
Drug absorption through mucous membranes (e.g., sublingual, buccal).
Systemic drug delivery
Systemic drug delivery
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First-pass metabolism
First-pass metabolism
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Transmucosal Administration
Transmucosal Administration
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Sublingual/Buccal Route
Sublingual/Buccal Route
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Pulmonary Drug Delivery
Pulmonary Drug Delivery
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Rectal Drug Delivery
Rectal Drug Delivery
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Routes of Drug Administration
Routes of Drug Administration
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Systemic Administration
Systemic Administration
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Local/Site-Specific Administration
Local/Site-Specific Administration
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Intravenous (IV) Administration
Intravenous (IV) Administration
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Intramuscular (IM) Administration
Intramuscular (IM) Administration
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Subcutaneous (SC) Administration
Subcutaneous (SC) Administration
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Topical Administration
Topical Administration
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Study Notes
I. Sublingual Route
- Drug is placed under the tongue
- Rapid absorption
- Directly into blood vessels
- Avoid first-pass metabolism
- Useful for treating angina pectoris & Vitamin B12
- Drug stability is necessary
II. Buccal Route
- Drug is placed between the gums and the cheek
- Slower absorption than sublingual
- Absorption is through the buccal mucosa
- Avoid first-pass metabolism
- Useful for treating angina pectoris
III. Alternate Routes for Systemic Drug Administration – Transmucosal
- Drugs are absorbed across mucus membranes
- Examples: Sublingual, Buccal, and Transmucosal
- Advantages: Increased absorption, avoids first-pass metabolism, and reduced dosage.
- Disadvantages: Limited absorption, unpleasant taste, and local irritation.
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