Pharmacology: Drug Administration Routes
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Questions and Answers

What is a primary advantage of the sublingual and buccal routes of drug administration?

  • Usually more cost-effective
  • Rapid absorption (correct)
  • Requires first-pass metabolism
  • Limited to large doses
  • Which of the following is a disadvantage of the pulmonary route for drug administration?

  • Difficulties in adjusting correct dose (correct)
  • Avoids first-pass metabolism
  • Rapid onset of action
  • Large surface area for absorption
  • What is a characteristic disadvantage of the rectal route of drug administration?

  • May cause irritation of mucosa (correct)
  • Absorption is quick and reliable
  • High concentration can be applied
  • Used for patients in stable condition
  • Which of the following is true regarding the advantages of the sublingual and buccal routes?

    <p>They avoid first-pass metabolism.</p> Signup and view all the answers

    Which statement accurately reflects a challenge associated with the pulmonary route?

    <p>It is often inconvenient.</p> Signup and view all the answers

    What is the primary method of absorption for drugs administered via the sublingual route?

    <p>Absorption through the sublingual mucosa</p> Signup and view all the answers

    Which condition is best treated by the sublingual route of drug administration?

    <p>Angina pectoris</p> Signup and view all the answers

    What is a characteristic of the buccal route of drug administration?

    <p>Longer duration of drug effect than sublingual</p> Signup and view all the answers

    Which of the following describes the common feature of alternate routes for systemic drug administration?

    <p>All routes aim for direct entry into systemic circulation</p> Signup and view all the answers

    What distinguishes transmucosal drug delivery from transdermal delivery?

    <p>Transmucosal involves absorption through mucous membranes</p> Signup and view all the answers

    What defines systemic administration of drugs?

    <p>Drugs are carried from the administration site to another site in the body.</p> Signup and view all the answers

    Which of the following is not a characteristic of parenteral drug administration?

    <p>It is always administered orally.</p> Signup and view all the answers

    What is first-pass metabolism?

    <p>The metabolism of a drug by the liver before it reaches systemic circulation.</p> Signup and view all the answers

    Which administration route allows for rapid onset of drug effects?

    <p>Intravenous (IV) administration.</p> Signup and view all the answers

    Which of the following routes is classified as local/site-specific administration?

    <p>Topical.</p> Signup and view all the answers

    What is a characteristic of inhalation as a drug delivery method?

    <p>Drugs are delivered in a gaseous form.</p> Signup and view all the answers

    Which method is not categorized under parenteral routes?

    <p>Transdermal.</p> Signup and view all the answers

    What type of drug administration would be appropriate for localized effects on injured tissue?

    <p>Topical administration.</p> Signup and view all the answers

    Study Notes

    I. Sublingual Route

    • Drug is placed under the tongue
    • Rapid absorption
    • Directly into blood vessels
    • Avoid first-pass metabolism
    • Useful for treating angina pectoris & Vitamin B12
    • Drug stability is necessary

    II. Buccal Route

    • Drug is placed between the gums and the cheek
    • Slower absorption than sublingual
    • Absorption is through the buccal mucosa
    • Avoid first-pass metabolism
    • Useful for treating angina pectoris

    III. Alternate Routes for Systemic Drug Administration – Transmucosal

    • Drugs are absorbed across mucus membranes
    • Examples: Sublingual, Buccal, and Transmucosal
    • Advantages: Increased absorption, avoids first-pass metabolism, and reduced dosage.
    • Disadvantages: Limited absorption, unpleasant taste, and local irritation.

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    Description

    This quiz covers the sublingual, buccal, and transmucosal routes of drug administration. Learn about their mechanisms, advantages, and applications in treating various conditions. Test your knowledge on how these methods help avoid first-pass metabolism and enhance drug absorption.

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