Pharmacology: Drug Administration Routes

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is a primary advantage of the sublingual and buccal routes of drug administration?

  • Usually more cost-effective
  • Rapid absorption (correct)
  • Requires first-pass metabolism
  • Limited to large doses

Which of the following is a disadvantage of the pulmonary route for drug administration?

  • Difficulties in adjusting correct dose (correct)
  • Avoids first-pass metabolism
  • Rapid onset of action
  • Large surface area for absorption

What is a characteristic disadvantage of the rectal route of drug administration?

  • May cause irritation of mucosa (correct)
  • Absorption is quick and reliable
  • High concentration can be applied
  • Used for patients in stable condition

Which of the following is true regarding the advantages of the sublingual and buccal routes?

<p>They avoid first-pass metabolism. (C)</p> Signup and view all the answers

Which statement accurately reflects a challenge associated with the pulmonary route?

<p>It is often inconvenient. (A)</p> Signup and view all the answers

What is the primary method of absorption for drugs administered via the sublingual route?

<p>Absorption through the sublingual mucosa (C)</p> Signup and view all the answers

Which condition is best treated by the sublingual route of drug administration?

<p>Angina pectoris (A)</p> Signup and view all the answers

What is a characteristic of the buccal route of drug administration?

<p>Longer duration of drug effect than sublingual (B)</p> Signup and view all the answers

Which of the following describes the common feature of alternate routes for systemic drug administration?

<p>All routes aim for direct entry into systemic circulation (C)</p> Signup and view all the answers

What distinguishes transmucosal drug delivery from transdermal delivery?

<p>Transmucosal involves absorption through mucous membranes (A)</p> Signup and view all the answers

What defines systemic administration of drugs?

<p>Drugs are carried from the administration site to another site in the body. (A)</p> Signup and view all the answers

Which of the following is not a characteristic of parenteral drug administration?

<p>It is always administered orally. (B)</p> Signup and view all the answers

What is first-pass metabolism?

<p>The metabolism of a drug by the liver before it reaches systemic circulation. (D)</p> Signup and view all the answers

Which administration route allows for rapid onset of drug effects?

<p>Intravenous (IV) administration. (D)</p> Signup and view all the answers

Which of the following routes is classified as local/site-specific administration?

<p>Topical. (A)</p> Signup and view all the answers

What is a characteristic of inhalation as a drug delivery method?

<p>Drugs are delivered in a gaseous form. (B)</p> Signup and view all the answers

Which method is not categorized under parenteral routes?

<p>Transdermal. (C)</p> Signup and view all the answers

What type of drug administration would be appropriate for localized effects on injured tissue?

<p>Topical administration. (A)</p> Signup and view all the answers

Flashcards

Sublingual Drug Administration

Drug placed under the tongue for rapid absorption into the bloodstream.

Buccal Drug Administration

Drug placed between cheek and gum for slower, sustained absorption.

Transmucosal drug delivery

Drug absorption through mucous membranes (e.g., sublingual, buccal).

Systemic drug delivery

Delivery of drugs into the bloodstream for widespread action throughout the body.

Signup and view all the flashcards

First-pass metabolism

Drug breakdown by the liver before reaching systemic circulation.

Signup and view all the flashcards

Transmucosal Administration

Delivering drugs through mucous membranes like the mouth, nose, or rectum, bypassing initial liver breakdown.

Signup and view all the flashcards

Sublingual/Buccal Route

Placing drugs under the tongue or between cheek and gum for quick absorption into the bloodstream.

Signup and view all the flashcards

Pulmonary Drug Delivery

Administering drugs through the lungs, often using inhalers, for fast action.

Signup and view all the flashcards

Rectal Drug Delivery

Administering drugs through the rectum, bypassing the stomach and liver.

Signup and view all the flashcards

Routes of Drug Administration

Different ways to introduce drugs into the body, categorized as systemic (affecting the whole body) or local/site-specific (affecting a specific area).

Signup and view all the flashcards

Systemic Administration

When a drug enters the bloodstream and travels throughout the body, impacting multiple tissues.

Signup and view all the flashcards

Local/Site-Specific Administration

When a drug is applied directly to a specific area, targeting the tissue that needs treatment.

Signup and view all the flashcards

Intravenous (IV) Administration

Injecting a drug directly into a vein, allowing for fast and direct entry into the bloodstream.

Signup and view all the flashcards

Intramuscular (IM) Administration

Injecting a drug into a muscle, enabling absorption into the bloodstream through muscle tissue.

Signup and view all the flashcards

Subcutaneous (SC) Administration

Injecting a drug under the skin, allowing for slower but sustained release into the bloodstream.

Signup and view all the flashcards

Topical Administration

Applying a drug directly to the skin or mucous membranes, providing localized treatment.

Signup and view all the flashcards

Study Notes

I. Sublingual Route

  • Drug is placed under the tongue
  • Rapid absorption
  • Directly into blood vessels
  • Avoid first-pass metabolism
  • Useful for treating angina pectoris & Vitamin B12
  • Drug stability is necessary

II. Buccal Route

  • Drug is placed between the gums and the cheek
  • Slower absorption than sublingual
  • Absorption is through the buccal mucosa
  • Avoid first-pass metabolism
  • Useful for treating angina pectoris

III. Alternate Routes for Systemic Drug Administration – Transmucosal

  • Drugs are absorbed across mucus membranes
  • Examples: Sublingual, Buccal, and Transmucosal
  • Advantages: Increased absorption, avoids first-pass metabolism, and reduced dosage.
  • Disadvantages: Limited absorption, unpleasant taste, and local irritation.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

More Like This

Use Quizgecko on...
Browser
Browser