Podcast
Questions and Answers
A patient with liver disease requires a medication that is primarily metabolized by the liver. Which adjustment to the standard dose would be most appropriate?
A patient with liver disease requires a medication that is primarily metabolized by the liver. Which adjustment to the standard dose would be most appropriate?
- Administer the standard dose.
- Decrease the dose; Hepatic impairment can reduce the rate of drug metabolism, leading to increased drug levels and potential toxicity.
- Increase the dose by 50%. (correct)
- Administer the medication intravenously to bypass first-pass metabolism.
An elderly patient with reduced kidney function is prescribed a drug that is eliminated primarily through the kidneys. What potential outcome should the nurse anticipate?
An elderly patient with reduced kidney function is prescribed a drug that is eliminated primarily through the kidneys. What potential outcome should the nurse anticipate?
- Altered drug absorption, requiring a higher initial dose.
- Increased drug excretion, leading to subtherapeutic effects. (correct)
- Decreased drug excretion, possibly leading to drug accumulation and toxicity.
- No significant change in drug response due to compensatory mechanisms.
Which property is least desirable in an ideal drug?
Which property is least desirable in an ideal drug?
- Selectivity: the drug elicits only the response for which it is given.
- Effectiveness: the drug elicits the responses for which it is given.
- Complex chemical structure: Drug's chemical composition is intricate.
- Reversible action: effects are reversible; drug actions need to cease after a while. (correct)
A patient is started on a new medication. After a few days, they report that the drug is not working as well as it did initially. What is the most likely explanation for this?
A patient is started on a new medication. After a few days, they report that the drug is not working as well as it did initially. What is the most likely explanation for this?
A drug has a half-life of 4 hours. If the initial plasma concentration is 200 mg/L, how much drug will remain in the body after 12 hours, assuming first-order kinetics?
A drug has a half-life of 4 hours. If the initial plasma concentration is 200 mg/L, how much drug will remain in the body after 12 hours, assuming first-order kinetics?
A nurse administers a drug directly into a patient's vein. Which phase of pharmacokinetics is effectively bypassed?
A nurse administers a drug directly into a patient's vein. Which phase of pharmacokinetics is effectively bypassed?
A patient is taking a drug that is known to be a CYP3A4 inducer. What effect might this have on other drugs the patient is taking?
A patient is taking a drug that is known to be a CYP3A4 inducer. What effect might this have on other drugs the patient is taking?
A patient is prescribed two drugs, A and B. Drug A is known to bind to albumin in the blood. If Drug B is also highly protein-bound, what potential interaction should the nurse monitor for?
A patient is prescribed two drugs, A and B. Drug A is known to bind to albumin in the blood. If Drug B is also highly protein-bound, what potential interaction should the nurse monitor for?
A nurse is preparing to administer an oral medication to a patient. Which factor is least likely to affect the rate of drug absorption?
A nurse is preparing to administer an oral medication to a patient. Which factor is least likely to affect the rate of drug absorption?
A prescriber orders a medication for a patient with a known allergy to that drug. What is the nurse's most appropriate action?
A prescriber orders a medication for a patient with a known allergy to that drug. What is the nurse's most appropriate action?
Flashcards
Pharmacokinetics
Pharmacokinetics
The study of how drugs move into, through, and out of the body. It includes absorption, distribution, metabolism, and excretion.
Pharmacodynamics
Pharmacodynamics
The study of how drugs affect the body, including the mechanism of action and the effects produced.
Adverse Drug Reactions
Adverse Drug Reactions
Unpredictable and unintended effects of a drug.
Nursing Responsibilities
Nursing Responsibilities
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Drug Preparation
Drug Preparation
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Properties of an Ideal Drug
Properties of an Ideal Drug
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Study Notes
- Focus is on understanding drugs, their preparations, and desired properties.
- Emphasis on pharmacokinetics and pharmacodynamics.
- Understanding variability in drug actions is crucial.
- Need to understand reactions across a lifespan.
- Need to understand individual differences between drugs.
- Focus on understanding nursing responsibilities related to drugs.
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Description
Explore pharmacology focusing on drug preparations, properties, pharmacokinetics, and pharmacodynamics. Learn about variability in drug actions across a lifespan, individual differences, and nursing responsibilities. Understand the core principles of pharmacology.
