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Pharmacology: Common Drug Reactions and Terminologies
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Pharmacology: Common Drug Reactions and Terminologies

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Questions and Answers

What is the definition of pharmacokinetics?

  • What the body does to drugs, encompassing drug interactions and metabolism (correct)
  • The process by which a drug is metabolized in the liver
  • The process by which a drug passively diffuses through the cell membrane
  • The process by which a drug binds to its target receptor
  • What enhances drug absorption according to the text?

  • Pain
  • Rich blood supply (correct)
  • Stress
  • Exercise
  • Which factor affects drug absorption by causing the drug to remain longer in the stomach?

  • Foods
  • Blood Flow
  • Pain (correct)
  • Exercise
  • In what type of environment are acidic drugs best absorbed according to the text?

    <p>Acidic environment</p> Signup and view all the answers

    How does exercise affect drug absorption, based on the information provided?

    <p>Decreases blood circulation to the muscles</p> Signup and view all the answers

    What is the term for the conjoint effect of two drugs being less than the effect of each drug acting separately?

    <p>Drug antagonism</p> Signup and view all the answers

    Which term describes the increasing response to repeated doses of a drug?

    <p>Cumulative effect</p> Signup and view all the answers

    In pharmacokinetics, what is the term for the decreased physiological response to repeated drug administration?

    <p>Drug tolerance</p> Signup and view all the answers

    What do you call the effect when two drugs are taken together, resulting in a combined effect greater than the sum of their individual effects?

    <p>Synergism</p> Signup and view all the answers

    Which term refers to the emotional reliance on a drug to maintain a sense of well-being?

    <p>Habituation</p> Signup and view all the answers

    What is the term for the unexpected peculiar response to a drug?

    <p>Idiosyncratic effect</p> Signup and view all the answers

    Which muscle is no longer recommended for intramuscular injections due to the discomfort and pain it may cause?

    <p>Rectus femoris</p> Signup and view all the answers

    Which type of solution has a lower osmotic pressure compared to another solution?

    <p>Hypertonic solution</p> Signup and view all the answers

    What is the most rapid route of absorption of medications?

    <p>Intravenous route</p> Signup and view all the answers

    What is a complication of IV infusion where the needle is out of the vein?

    <p>Infiltration</p> Signup and view all the answers

    Which intervention should be performed if pain, swelling, or decreased IV flow rate is observed during IV infusion?

    <p>Change the site of the needle</p> Signup and view all the answers

    Study Notes

    Anaphylactic Reaction and Drug Effects

    • Anaphylactic reaction is a severe allergic reaction that occurs immediately after drug administration.
    • Drug tolerance refers to a decreased physiologic response to repeated administration of a drug or chemically related substance.
    • Cumulative effect is the increasing response to repeated doses of a drug.
    • Idiosyncratic effect is an unexpected peculiar response to a drug.
    • Drug abuse is the inappropriate intake of a substance, either continually or periodically.
    • Drug dependence is a person's reliance or need to take a drug or substance.
    • Addiction is caused by biochemical changes in body tissues, especially the nervous system.
    • Habituation is emotional reliance on a drug to maintain a sense of well-being.

    Drug Interactions

    • Drug interaction occurs when the effects of one drug are modified by the prior or concurrent administration of another drug.
    • Drug antagonism is when the conjoint effect of two drugs is less than the effect of each drug acting separately.
    • Summation is when the combined effect of two drugs equals the sum of the individual effects of each agent.
    • Synergism is when the combined effects of drugs are greater than the sum of each individual agent acting independently.
    • Potentiation is when the concurrent administration of two drugs increases the effect of one drug.

    Therapeutic Actions of Drugs

    • Palliative actions relieve the symptoms of a disease but do not affect the disease itself.
    • Curative actions treat a disease or condition.
    • Supportive actions sustain body functions until other treatments or the body's response can take over.
    • Substitutive actions replace body fluids or substances.
    • Chemotherapeutic actions destroy malignant cells.
    • Restorative actions return the body's health.

    Pharmacokinetics

    • Pharmacokinetics refers to what the body does to drugs and encompasses all issues of drug interactions and drug clearance metabolism.
    • Absorption is the process by which a drug passes from its site of administration into the bloodstream.
    • Factors that affect drug absorption include blood flow, pain, stress, foods, exercise, nature of the absorbing surface, solubility of the drug, and pH.
    • IM injection sites commonly used are the deltoid, dorsogluteal, rectus femoris, vastus lateralis, and ventrogluteal muscles.
    • Types of muscle include striated muscle (skeletal muscle), smooth muscle (internal organs), and cardiac muscle.

    Intravenous Route

    • The intravenous route is the most rapid route of absorption of medications.
    • Isotonic solutions are IV fluids that have a similar concentration of dissolved particles as blood.
    • Complications of IV infusion include infiltration, which occurs when the needle is out of the vein.
    • Signs of infiltration include pain, swelling, skin is cold at the needle site, pallor of the site, and a decrease or stop in the flow of IV rate.
    • Nursing interventions for infiltration include changing the site of the needle.

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    Description

    Test your knowledge on common drug reactions and terminologies in pharmacology. Explore concepts such as anaphylactic reaction, drug tolerance, cumulative effect, idiosyncratic effect, drug abuse, and drug dependence.

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