Pharmacology: Cholinergic Antagonists Atropine

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

What is the primary mechanism of action of atropine?

  • Competitive nicotinic ganglion blocker
  • Antimuscarinic receptor antagonist (correct)
  • Depolarization of ganglia ANS and striated muscle
  • Inhibition of neuromuscular transmission

Which of the following is a therapeutic use of scopolamine?

  • Relief of uveitis
  • Treatment of Parkinson's disease
  • Antidote for organophosphate toxicity
  • MANAGEMENT OF MOTION SICKNESS (correct)

What is the primary difference between atropine and scopolamine?

  • Atropine is used as an antidote for organophosphate toxicity
  • Scopolamine is an agonist at muscarinic receptors
  • Scopolamine is used to treat uveitis
  • Scopolamine has a longer duration of action in the CNS (correct)

What is the primary mechanism of action of ipratropium?

<p>Antimuscarinic receptor antagonist (C)</p> Signup and view all the answers

Benztropine is primarily used as an adjuvant treatment for which condition?

<p>Parkinson's disease (C)</p> Signup and view all the answers

What is the primary effect of cholinergic antagonists on the urinary system?

<p>Decreased urination (C)</p> Signup and view all the answers

What is the primary pharmacokinetic characteristic of atropine?

<p>Readily absorbed and partially metabolized in the liver (C)</p> Signup and view all the answers

Which of the following is a side effect of cholinergic antagonists?

<p>Dry mouth (A)</p> Signup and view all the answers

What is the primary therapeutic use of darifenacin?

<p>Treatment of overactive bladder (C)</p> Signup and view all the answers

What is the primary mechanism of action of trimethaphan?

<p>Competitive nicotinic ganglion blocker (C)</p> Signup and view all the answers

What is the primary mechanism of action of competitive nicotinic ganglion blockers like mecamylamine?

<p>Competing with acetylcholine for nicotinic receptors (A)</p> Signup and view all the answers

What is the main difference between depolarizing and non-depolarizing neuromuscular blockers?

<p>Depolarizing blockers cause prolonged stimulation and subsequent desensitization of the receptors, while non-depolarizing blockers compete with acetylcholine for receptors (C)</p> Signup and view all the answers

What is the primary therapeutic use of Curane?

<p>Muscle relaxation during surgery (B)</p> Signup and view all the answers

What is the primary mechanism of action of benzodiazepines?

<p>Enhancing the activity of gamma-aminobutyric acid (GABA) (C)</p> Signup and view all the answers

What is the primary use of rocuronium?

<p>Facilitating tracheal intubation during anesthesia (C)</p> Signup and view all the answers

What is the primary effect of nicotine on dopamine levels?

<p>Increase in dopamine, leading to pleasure and appetite suppression (A)</p> Signup and view all the answers

What is the primary effect of mecamylamine on blood pressure?

<p>Increase in blood pressure, leading to hypertension (A)</p> Signup and view all the answers

Which cholinergic antagonist has a stronger central nervous system effect than atropine?

<p>Scopolamine (B)</p> Signup and view all the answers

What is the primary therapeutic use of ipratropium and tiotropium?

<p>Asthma and COPD (D)</p> Signup and view all the answers

Which of the following cholinergic antagonists is used to treat overactive bladder?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary mechanism of action of trimethaphan?

<p>Competitive nicotinic ganglion blocker (D)</p> Signup and view all the answers

What is the primary effect of nicotine on the autonomic nervous system?

<p>Depolarization of ganglia and striated muscle (B)</p> Signup and view all the answers

Which of the following is a common side effect of cholinergic antagonists?

<p>Dry mouth (C)</p> Signup and view all the answers

What is the primary therapeutic use of tropicamide?

<p>Cycloplegic refraction and uveitis (C)</p> Signup and view all the answers

What is the primary mechanism of action of benztropine?

<p>Centrally acting antimuscarinic agent (D)</p> Signup and view all the answers

What is the primary effect of atropine on the eye?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary mechanism of action of mecamylamine in the treatment of hypertension?

<p>Competitive inhibition of nicotinic receptors in the ganglion (D)</p> Signup and view all the answers

What is the primary effect of nicotine on glutamate levels?

<p>Increased release of glutamate (B)</p> Signup and view all the answers

What is the primary mechanism of action of non-depolarizing neuromuscular blockers?

<p>Competitive inhibition of acetylcholine receptors (C)</p> Signup and view all the answers

What is the primary therapeutic use of succinylcholine?

<p>Rapid endotracheal intubation during induction of anesthesia (D)</p> Signup and view all the answers

What is the primary effect of benzodiazepines on GABA?

<p>Enhancement of GABA's inhibitory effects (A)</p> Signup and view all the answers

What is the primary adverse effect of succinylcholine?

<p>Hyperthermia (C)</p> Signup and view all the answers

What is the primary mechanism of action of succinylcholine?

<p>Depolarization of the neuromuscular junction (A)</p> Signup and view all the answers

What is the primary effect of nicotine on norepinephrine levels?

<p>Increased release of norepinephrine (C)</p> Signup and view all the answers

Flashcards are hidden until you start studying

Related Documents

Pharm Exam 2 PDF

More Like This

Use Quizgecko on...
Browser
Open
Browser
Browser