Pharmacology Chapter 6 Quiz
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Questions and Answers

What is the primary function of oxytocics during labor?

  • Increase uterine blood flow
  • Induce uterine contractions (correct)
  • Promote fetal growth
  • Relieve maternal pain
  • Which of the following is true about tocolytics?

  • They are used to promote preterm labor
  • They stop preterm labor (correct)
  • They induce labor when it is not progressing
  • They support the development of fetal organs
  • What condition is characterized by grand mal seizures during pregnancy?

  • Hyperemesis gravidarum
  • Gestational diabetes
  • Preeclampsia
  • Eclampsia (correct)
  • What is a safe herb category to stimulate lactation?

    <p>Galactagogues</p> Signup and view all the answers

    Which of the following statements about iron deficiency anemia in pregnancy is correct?

    <p>Increase of iron consumption should be around 30mg per day for most.</p> Signup and view all the answers

    What is the main cause of constipation during pregnancy?

    <p>Smooth muscle relaxation and decreased peristalsis</p> Signup and view all the answers

    Which substance should be avoided as a laxative during pregnancy?

    <p>Oil-based laxatives</p> Signup and view all the answers

    Which maternal condition involves hypertension and proteinuria?

    <p>Preeclampsia</p> Signup and view all the answers

    Which nutrient is crucial to prevent neural tube defects during pregnancy?

    <p>Folic acid</p> Signup and view all the answers

    Which drug category is used to manage postpartum hemorrhage?

    <p>Oxytocics</p> Signup and view all the answers

    What effect does progesterone have on cholesterol levels?

    <p>Decreases HDL cholesterol and increases LDL cholesterol</p> Signup and view all the answers

    When should Indomethacin not be recommended during pregnancy?

    <p>After 32 weeks of gestation or longer than 48 hours</p> Signup and view all the answers

    What condition is characterized by the progression of preeclampsia leading to seizures?

    <p>Eclampsia</p> Signup and view all the answers

    What is a common initial medicinal approach to address nausea in pregnant women experiencing hyperemesis gravidarum?

    <p>Antihistamines and dopamine antagonists</p> Signup and view all the answers

    What condition signifies glucose intolerance that occurs specifically during pregnancy?

    <p>Gestational diabetes</p> Signup and view all the answers

    Which medication is contraindicated for patients with myasthenia gravis?

    <p>Magnesium sulfate</p> Signup and view all the answers

    What hormone is primarily responsible for promoting tissue growth in women?

    <p>Estrogen</p> Signup and view all the answers

    What is a significant risk associated with maternal hyperglycemia during pregnancy?

    <p>Congenital deformities in the fetus</p> Signup and view all the answers

    What is the potential adverse effect of Nifedipine during pregnancy?

    <p>Hypotension reducing blood flow to the fetus</p> Signup and view all the answers

    What adverse effect can occur with prolonged administration of Terbutaline Sulfate?

    <p>Tachycardia and palpitations</p> Signup and view all the answers

    What is the primary function of estrogens in hormonal contraceptives?

    <p>Inhibit hypothalamic secretions of GnRH</p> Signup and view all the answers

    Which of the following conditions is a contraindication for estrogen therapy?

    <p>History of thromboembolic disorders</p> Signup and view all the answers

    How does transdermal estrogen administration differ from oral administration?

    <p>Transdermal avoids first-pass metabolism and results in lower estrogen levels</p> Signup and view all the answers

    What is the primary action of progestin in hormonal therapy?

    <p>Inhibit ovarian function</p> Signup and view all the answers

    What is one reason why estrogen replacement therapy (ERT) is prescribed?

    <p>To treat symptoms of estrogen deficiency in postmenopausal women</p> Signup and view all the answers

    What effect does combined estrogen-progestin therapy have on ovulation?

    <p>Prevents ovulation</p> Signup and view all the answers

    Which of the following is a potential adverse effect of estrogen therapy?

    <p>Nausea and vomiting</p> Signup and view all the answers

    What is the appropriate timing for taking emergency contraception using birth control pills?

    <p>First dose within 120 hours, second dose 12 hours later</p> Signup and view all the answers

    Which effect is NOT associated with the use of estrogens?

    <p>Induction of uterine contractions</p> Signup and view all the answers

    What must be monitored while a patient is on progestin therapy?

    <p>Glucose levels and weight gain</p> Signup and view all the answers

    What is the recommended dietary practice for pregnant women to help mitigate nausea?

    <p>Consume small meals frequently.</p> Signup and view all the answers

    What are common side effects of magnesium sulfate administration in pregnant women?

    <p>Respiratory depression and hypotension.</p> Signup and view all the answers

    Which of the following increases the risk of developing gestational diabetes?

    <p>Previous history of diabetes.</p> Signup and view all the answers

    Which medication is contraindicated for women with a history of myasthenia gravis?

    <p>Magnesium sulfate.</p> Signup and view all the answers

    What is a significant concern associated with the use of tocolytics like Indomethacin?

    <p>Risk of oligohydramnios.</p> Signup and view all the answers

    Which hormone is predominantly responsible for changes in the endometrial lining after ovulation?

    <p>Progesterone.</p> Signup and view all the answers

    What is the risk associated with fetal exposure to Terbutaline sulfate?

    <p>Hypoglycemia.</p> Signup and view all the answers

    What is a key contraindication for the use of oxytocin during labor?

    <p>Fetal distress.</p> Signup and view all the answers

    What should be monitored when administering nifedipine to a pregnant patient?

    <p>Maternal blood pressure.</p> Signup and view all the answers

    What is an appropriate medicational approach if antihistamines are ineffective for nausea in pregnancy?

    <p>Total parenteral nutrition.</p> Signup and view all the answers

    What is a common treatment approach for managing iron deficiency anemia during pregnancy?

    <p>Increase of iron consumption to 30 mg per day</p> Signup and view all the answers

    Which statement accurately describes the action of oxytocics?

    <p>Oxytocics stimulate uterine contractions during labor</p> Signup and view all the answers

    Which drug class is NOT effective in stopping preterm labor?

    <p>Oxytocics</p> Signup and view all the answers

    What is one of the key characteristics of eclampsia during pregnancy?

    <p>Presence of grand mal seizures</p> Signup and view all the answers

    What dietary component is recommended for preventing neural tube defects in pregnancy?

    <p>Folic acid of 400-600 mcg</p> Signup and view all the answers

    What type of laxative is considered safest for pregnant women?

    <p>Stool softeners like docusate</p> Signup and view all the answers

    Which herb is deemed safe for use during pregnancy?

    <p>Red raspberry leaf</p> Signup and view all the answers

    What condition is characterized by hypertension and proteinuria during pregnancy?

    <p>Preeclampsia</p> Signup and view all the answers

    Which type of drug can contribute to abnormal fetal development?

    <p>Teratogenic drugs</p> Signup and view all the answers

    What is the role of tocolytics in pregnancy management?

    <p>Stop preterm labor</p> Signup and view all the answers

    What is the primary action of estrogens in the body?

    <p>To stimulate cell reproduction and interact with DNA</p> Signup and view all the answers

    What is the primary reason estrogen replacement therapy (ERT) is prescribed?

    <p>To relieve symptoms of estrogen deficiency and prevent osteoporosis</p> Signup and view all the answers

    What major adverse effect is associated with long-term use of estrogen therapy?

    <p>Increased risk of endometrial cancer</p> Signup and view all the answers

    What is a contraindication for the use of progestin therapy?

    <p>Undiagnosed vaginal bleeding</p> Signup and view all the answers

    Which statement about the pharmacokinetics of oral contraceptives is true?

    <p>Intramuscular progestin has a half-life of minutes</p> Signup and view all the answers

    What is an action of progestins in hormonal therapy?

    <p>They inhibit spontaneous uterine contractions</p> Signup and view all the answers

    What can the combination of estrogen and progestin in birth control pills specifically prevent?

    <p>Pregnancy by inhibiting ovulation</p> Signup and view all the answers

    Which population should be particularly cautious about taking estrogen therapy?

    <p>Women who smoke and are over 35 years old</p> Signup and view all the answers

    For which reason might progestin be used as an emergency contraceptive?

    <p>To suppress ovarian function after unprotected intercourse</p> Signup and view all the answers

    What should patients taking hormonal contraceptives monitor regularly?

    <p>Weight and report any significant changes</p> Signup and view all the answers

    Study Notes

    Key Terms

    • Abortifacients: Drugs used for terminating pregnancy.
    • Eclampsia: Characterized by the onset of grand mal seizures during pregnancy.
    • Galactagogues: Herbs used to stimulate lactation or increase milk production.
    • Organogenesis: The process of organ formation during pregnancy.
    • Oxytocics: Agents that induce uterine contractions and childbirth.
    • Preeclampsia: Pregnancy-associated hypertension with proteinuria and end-organ failure.
    • Preterm Labor: Labor occurring before 37 weeks of gestation.
    • Prostaglandins: Compounds that facilitate uterine contractions.
    • Teratogenic: Substances that can cause abnormal fetal development.
    • Tocolytics: Medications used to stop preterm labor.
    • Uterotonics: Agents that help stop postpartum bleeding.

    Drug Effects on Fetus

    • Certain herbal remedies (red raspberry leaf, peppermint, ginger, slippery elm bark, oats, and oat straw) are considered safe during pregnancy.
    • Folic acid intake of 400-600 mcg is essential for fetal development.

    Management of Pregnancy Symptoms

    • Anemia: Physiologic anemia presents with hemoglobin < 11 g/dL; iron deficiency requires daily intake of 30 mg + 60-200 mg additional until corrected.
    • Constipation: Caused by smooth muscle relaxation; increase fiber and fluids. Safe laxatives include psyllium and docusate, while oil-based laxatives should be avoided.
    • GERD: Heartburn results from hormonal changes; recommend small meals, avoid certain foods, and consider safe antacids.
    • Gestational Diabetes: Diagnosed with elevated glucose levels; can lead to complications such as fetal hyperinsulinemia. Insulin is safe while metformin or glyburide can be alternatives.
    • Nausea and Vomiting: Often due to hormone levels; initial treatment includes antihistamines, with total parenteral nutrition for severe cases.
    • Hypertensive Disorders: Include preeclampsia and eclampsia; magnesium sulfate is used for management, with calcium gluconate as an antidote for magnesium overdose.

    Tocolytics

    • Indomethacin: Inhibits prostaglandins; not recommended after 32 weeks. Possible adverse effects include nausea and reduced amniotic fluid.
    • Nifedipine: A calcium channel blocker that reduces contractions; monitor for hypotension and avoid in unstable patients.
    • Terbutaline Sulfate: A beta-agonist that reduces contractions but may cause tachycardia and other adverse reactions; contraindicated in certain conditions such as hyperthyroidism.
    • Magnesium Sulfate: Administered intravenously to prevent preterm birth and protect the fetus's nervous system; contraindicated in myasthenia gravis.

    Oxytocics and Uterotonics

    • Oxytocin (Pitocin): Synthetic oxytocin used to induce labor; contraindicated in fetal distress; monitor for excessive uterine stimulation.
    • Uterotonics: Used to control postpartum hemorrhage; oxytocin is typically the first-line choice post-delivery.
    • Carboprost Tromethamine: Stimulates uterine contractions; contraindicated in allergies and certain cardiovascular conditions.
    • Methylergonovine: Increases contraction strength and frequency; monitor for hypertension and other symptoms post-administration.
    • Misoprostol: Used for cervical ripening and postpartum hemorrhage management.

    Estrogen and Progestins

    Estrogen

    • Promotes growth in female tissues, primarily estradiol.
    • Regulates menstrual cycles and plays a role in pregnancy.
    • Various administration forms exist, including oral and transdermal.
    • Common uses include hormonal replacement therapy and birth control formulations.

    Progesterone

    • Regulates endometrial changes for implantation.
    • Synthetic form (Medroxyprogesterone acetate) is used for contraceptive purposes and managing menstrual disorders.
    • Long-term use can lead to cardiovascular complications and other side effects.

    Estrogen-Progestin Combinations

    • Effective in preventing pregnancy by inhibiting ovulation and altering the endometrial lining.
    • Common side effects include GI issues and cardiovascular risks; contraindicated with certain conditions and medications.

    Nursing Implications and Patient Teaching

    • Assess patient history, risk factors, and need for contraception.
    • Regular monitoring and education on signs of complications or medication interactions are essential.
    • Importance of backup contraception for certain hormonal therapies.

    Key Terms

    • Abortifacients: Drugs used for terminating pregnancy.
    • Eclampsia: Characterized by the onset of grand mal seizures during pregnancy.
    • Galactagogues: Herbs used to stimulate lactation or increase milk production.
    • Organogenesis: The process of organ formation during pregnancy.
    • Oxytocics: Agents that induce uterine contractions and childbirth.
    • Preeclampsia: Pregnancy-associated hypertension with proteinuria and end-organ failure.
    • Preterm Labor: Labor occurring before 37 weeks of gestation.
    • Prostaglandins: Compounds that facilitate uterine contractions.
    • Teratogenic: Substances that can cause abnormal fetal development.
    • Tocolytics: Medications used to stop preterm labor.
    • Uterotonics: Agents that help stop postpartum bleeding.

    Drug Effects on Fetus

    • Certain herbal remedies (red raspberry leaf, peppermint, ginger, slippery elm bark, oats, and oat straw) are considered safe during pregnancy.
    • Folic acid intake of 400-600 mcg is essential for fetal development.

    Management of Pregnancy Symptoms

    • Anemia: Physiologic anemia presents with hemoglobin < 11 g/dL; iron deficiency requires daily intake of 30 mg + 60-200 mg additional until corrected.
    • Constipation: Caused by smooth muscle relaxation; increase fiber and fluids. Safe laxatives include psyllium and docusate, while oil-based laxatives should be avoided.
    • GERD: Heartburn results from hormonal changes; recommend small meals, avoid certain foods, and consider safe antacids.
    • Gestational Diabetes: Diagnosed with elevated glucose levels; can lead to complications such as fetal hyperinsulinemia. Insulin is safe while metformin or glyburide can be alternatives.
    • Nausea and Vomiting: Often due to hormone levels; initial treatment includes antihistamines, with total parenteral nutrition for severe cases.
    • Hypertensive Disorders: Include preeclampsia and eclampsia; magnesium sulfate is used for management, with calcium gluconate as an antidote for magnesium overdose.

    Tocolytics

    • Indomethacin: Inhibits prostaglandins; not recommended after 32 weeks. Possible adverse effects include nausea and reduced amniotic fluid.
    • Nifedipine: A calcium channel blocker that reduces contractions; monitor for hypotension and avoid in unstable patients.
    • Terbutaline Sulfate: A beta-agonist that reduces contractions but may cause tachycardia and other adverse reactions; contraindicated in certain conditions such as hyperthyroidism.
    • Magnesium Sulfate: Administered intravenously to prevent preterm birth and protect the fetus's nervous system; contraindicated in myasthenia gravis.

    Oxytocics and Uterotonics

    • Oxytocin (Pitocin): Synthetic oxytocin used to induce labor; contraindicated in fetal distress; monitor for excessive uterine stimulation.
    • Uterotonics: Used to control postpartum hemorrhage; oxytocin is typically the first-line choice post-delivery.
    • Carboprost Tromethamine: Stimulates uterine contractions; contraindicated in allergies and certain cardiovascular conditions.
    • Methylergonovine: Increases contraction strength and frequency; monitor for hypertension and other symptoms post-administration.
    • Misoprostol: Used for cervical ripening and postpartum hemorrhage management.

    Estrogen and Progestins

    Estrogen

    • Promotes growth in female tissues, primarily estradiol.
    • Regulates menstrual cycles and plays a role in pregnancy.
    • Various administration forms exist, including oral and transdermal.
    • Common uses include hormonal replacement therapy and birth control formulations.

    Progesterone

    • Regulates endometrial changes for implantation.
    • Synthetic form (Medroxyprogesterone acetate) is used for contraceptive purposes and managing menstrual disorders.
    • Long-term use can lead to cardiovascular complications and other side effects.

    Estrogen-Progestin Combinations

    • Effective in preventing pregnancy by inhibiting ovulation and altering the endometrial lining.
    • Common side effects include GI issues and cardiovascular risks; contraindicated with certain conditions and medications.

    Nursing Implications and Patient Teaching

    • Assess patient history, risk factors, and need for contraception.
    • Regular monitoring and education on signs of complications or medication interactions are essential.
    • Importance of backup contraception for certain hormonal therapies.

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    Description

    Test your knowledge on key pharmacological terms and drugs related to infertility and maternal therapeutics. This quiz covers drug effects on the fetus, management of pregnancy-associated symptoms, and specific drugs such as Tocolytics and Oxytocics. Enhance your understanding of crucial topics in maternal health and pharmacology.

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