Pharmacology Chapter 3 Flashcards
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Pharmacology Chapter 3 Flashcards

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What is pharmacology?

Integrated medical science involving chemistry, biochemistry, anatomy, physiology, microbiology, and the study of drugs, their actions, dosage, therapeutic uses, and adverse effects.

What is drug therapy?

Drug therapy is directly linked to the pathophysiology of a particular disease and includes sources such as natural sources from plants, animals, and microorganisms, as well as synthesized drugs.

What can drugs do?

Promote healing, cure disease, control or slow disease progress, prevent disease, alter neurotransmission, decrease the risk of complications, increase function and comfort, provide replacement therapy, and reduce excessive activity in the body.

What is pharmacodynamics?

<p>The study of how drugs work.</p> Signup and view all the answers

What is pharmacokinetics?

<p>The study of the movement of drugs in the body, according to sites of administration.</p> Signup and view all the answers

What is pharmacotherapeutics?

<p>Preventing or treating disease with medication.</p> Signup and view all the answers

What is toxicology?

<p>The study of the body's response to drugs.</p> Signup and view all the answers

What is pharmacy?

<p>Preparing, dispensing, proper use and follow-up of the use of drugs.</p> Signup and view all the answers

What does 'therapeutic' refer to in pharmacology?

<p>The desired effect; stimulating or inhibiting cell function; blocking biochemical actions in tissues.</p> Signup and view all the answers

What are drug classifications?

<p>Grouped by their primary pharmacologic action and effect.</p> Signup and view all the answers

What are indications in pharmacology?

<p>Approved uses to treat conditions for which the drug has been proved to be effective.</p> Signup and view all the answers

What are contraindications?

<p>When a drug should not be used.</p> Signup and view all the answers

What are side effects?

<p>Mild, undesirable effects of a drug, even at recommended doses.</p> Signup and view all the answers

What are adverse or toxic effects?

<p>Drug effects that are dangerous, cause significant tissue damage, or are life-threatening.</p> Signup and view all the answers

What does hypersensitivity refer to in relation to drugs?

<p>Allergic reaction; reactions may be mild or can result in anaphylaxis.</p> Signup and view all the answers

What is an idiosyncratic reaction?

<p>Unusual responses to a drug.</p> Signup and view all the answers

What does iatrogenic mean?

<p>Negative effect associated with the administration of a drug.</p> Signup and view all the answers

What does teratogenic mean?

<p>Harmful effects on the fetus, leading to developmental defects.</p> Signup and view all the answers

What are interactions in pharmacology?

<p>Drug effects modified by combining it with another one.</p> Signup and view all the answers

What is synergism?

<p>The effect of drug combination may be greater than the sum of the effects of the individual drugs.</p> Signup and view all the answers

What is antagonism in pharmacology?

<p>Combination greatly decreases the effect of each drug.</p> Signup and view all the answers

What is potentiation?

<p>One drug enhances the effect of the second one.</p> Signup and view all the answers

What is a dose in pharmacology?

<p>The amount of drug required to produce the desired effect in an adult, expressed by weight or measure.</p> Signup and view all the answers

How is a child's dose calculated?

<p>Best calculated by the child's weight, not age.</p> Signup and view all the answers

What is a loading dose?

<p>A larger dose may be administered initially to raise blood levels to an effective level.</p> Signup and view all the answers

What is frequency of dosing?

<p>Important to maintain effective blood levels of the drug without reaching toxic levels.</p> Signup and view all the answers

What is an optimum dosing schedule?

<p>Established for each drug based on absorption, transport in the blood, half-life of the drug.</p> Signup and view all the answers

What is a timing schedule in pharmacology?

<p>Directions regarding timing related to meals, daily events, and sleep.</p> Signup and view all the answers

What factors affect blood levels of drugs?

<p>Liver and kidney function, absorption and excretion, circulation, age, body weight, activity level, food intake, genetic factors, health status.</p> Signup and view all the answers

How can drugs be administered?

<p>Drugs can be administered for acting locally or have a systemic action.</p> Signup and view all the answers

What is oral medication?

<p>Taken by mouth and has a long time to be absorbed.</p> Signup and view all the answers

What is sublingual administration?

<p>Administration under the tongue for immediate absorption.</p> Signup and view all the answers

What is parenteral administration?

<p>Administration via injection, gradually absorbed into the blood.</p> Signup and view all the answers

What is inhalation in pharmacology?

<p>Administration through the respiratory tract for rapid onset absorption.</p> Signup and view all the answers

What is topical (transdermal) administration?

<p>Applied on skin or mucous membranes for rapid onset, with few systemic effects.</p> Signup and view all the answers

What is drug absorption?

<p>Most drugs are metabolized in the liver and excreted in the kidneys.</p> Signup and view all the answers

What is the role of receptors in drug action?

<p>Common pharmacologic action requires drug-receptor interaction.</p> Signup and view all the answers

What must a signed legal document for drug administration include?

<p>Patient's name, address, and age; prescriber's information; date; name and amount of drug; dosage; route; and directions for use.</p> Signup and view all the answers

What is a generic name in pharmacology?

<p>Unique, official, simple name for a specific drug, e.g., acetaminophen.</p> Signup and view all the answers

What is a trade name?

<p>Proprietary or brand name assigned by the manufacturer, e.g., Tylenol.</p> Signup and view all the answers

What is a chemical name?

<p>The chemical component of a drug, e.g., acetylsalicylic acid.</p> Signup and view all the answers

What is drug regulation?

<p>FDA regulates the production, labeling, distribution, and other aspects of drug control.</p> Signup and view all the answers

What does 'PO' stand for?

<p>Orally by mouth.</p> Signup and view all the answers

What does 'IM' stand for?

<p>Intramuscularly.</p> Signup and view all the answers

What does 'SQ' stand for?

<p>Subcutaneously.</p> Signup and view all the answers

What does 'BID' mean?

<p>Twice a day.</p> Signup and view all the answers

What does 'TID' mean?

<p>Three times a day.</p> Signup and view all the answers

What does 'QID' mean?

<p>Four times a day.</p> Signup and view all the answers

What does 'IV' stand for?

<p>Intravenous.</p> Signup and view all the answers

What does 'OD' mean?

<p>Right eye.</p> Signup and view all the answers

What does 'OS' mean?

<p>Left eye.</p> Signup and view all the answers

What does 'OU' mean?

<p>Both eyes.</p> Signup and view all the answers

What does 'QD' mean?

<p>Everyday.</p> Signup and view all the answers

What does 'Q 4 hr' mean?

<p>Every 4 hours.</p> Signup and view all the answers

What does 'HS' stand for?

<p>At bedtime.</p> Signup and view all the answers

What does 'ac' mean?

<p>Before meals.</p> Signup and view all the answers

What does 'pc' mean?

<p>After meals.</p> Signup and view all the answers

What does 'prn' mean?

<p>As needed.</p> Signup and view all the answers

Study Notes

Pharmacology Overview

  • Pharmacology integrates multiple medical sciences including chemistry, biochemistry, anatomy, physiology, and microbiology.
  • It involves the study of drugs, including their actions, dosages, therapeutic uses, and adverse effects.

Drug Therapy

  • Drug therapy is closely related to the disease's pathophysiology.
  • Drugs can originate from natural sources like plants, animals, and microorganisms or be synthesized.

Drug Functions

  • Drugs can promote healing (e.g., anti-inflammatories), cure diseases (e.g., antibacterials), control or slow disease progress (e.g., chemotherapy), and prevent diseases (e.g., vaccines).
  • They can influence neurotransmission (e.g., antidepressants), decrease complication risks (e.g., anticoagulants), enhance function and comfort (e.g., analgesics), provide replacement therapy (e.g., insulin, estrogen), and reduce excessive bodily activity (e.g., proton pump inhibitors).

Pharmacodynamics & Pharmacokinetics

  • Pharmacodynamics focuses on how drugs exert their effects.
  • Pharmacokinetics studies the movement of drugs within the body based on the routes of administration.

Pharmacotherapeutics & Toxicology

  • Pharmacotherapeutics involves using medications to prevent or treat diseases.
  • Toxicology examines the body’s reactions to drugs, focusing on both harmful and beneficial effects.

Pharmacy Practice

  • Pharmacy encompasses the preparation, dispensing, and management of drug use for safe and effective patient care.

Drug Classifications

  • Drugs are classified based on their primary pharmacologic actions and effects.

Indications and Contraindications

  • Indications refer to approved uses of drugs for specific conditions.
  • Contraindications are specific scenarios where a drug should not be used.

Side Effects and Adverse Reactions

  • Side effects are mild undesirable effects that may occur even at recommended doses.
  • Adverse effects can be dangerous, cause significant harm, or even be life-threatening.

Unique Drug Reactions

  • Hypersensitivity relates to allergic reactions; reactions may vary from mild to severe (anaphylaxis).
  • Idiosyncratic reactions are unusual responses that differ from typical drug effects.
  • Iatrogenic effects are negative outcomes associated with drug administration.
  • Teratogenic effects refer to developmental defects caused by drug exposure to a fetus.

Drug Interactions

  • Interactions modify drug effects when combined with other drugs.
  • Synergism occurs when combined drugs produce a greater effect than the sum of individual effects.
  • Antagonism results in diminished effects when drugs are combined.
  • Potentiation happens when one drug enhances the effect of another.

Dosing Considerations

  • Dosage is the amount of drug required for the desired effect, calculated by weight, measure, and frequency.
  • Children's doses are determined primarily by weight, not age.
  • A loading dose can be initially administered to quickly raise drug levels in the bloodstream.
  • Frequency of dosing is critical to maintain effective blood levels without toxicity.

Routes of Drug Administration

  • Oral medications are absorbed slowly and require processing by the liver.
  • Sublingual medications are absorbed immediately under the tongue.
  • Parenteral (injection) routes vary in absorption speed: subcutaneous (slow), intramuscular (moderate), and intravenous (immediate).
  • Inhalation provides rapid absorption directly into the respiratory tract.
  • Topical preparations can have varying speeds of absorption, with mucous membranes absorbing more quickly than skin.

Drug Absorption and Metabolism

  • Drugs are generally metabolized in the liver and excreted by the kidneys, though some can be expelled through bile or feces.
  • Barriers, such as the blood-brain barrier and placental barrier, can impede drug absorption.

Drug-Receptor Interaction

  • Drug actions typically involve interactions with specific receptors.
  • Drugs may directly stimulate or block receptors, influencing cellular functions and biochemical processes.
  • Prescriptions must include patient and prescriber information, drug details, dosage, and usage instructions.
  • Generic names identify drugs uniquely, while trade names are manufacturer-specific. Chemical names specify the drug's chemical structure.
  • The FDA regulates drug production, labeling, and distribution; scheduled drugs are monitored for abuse potential, while OTC drugs are available without prescriptions.

Abbreviation Guide

  • PO: orally by mouth
  • IM: intramuscularly
  • SQ: subcutaneously
  • BID: twice a day
  • TID: three times a day
  • QID: four times a day
  • IV: intravenous
  • OD: right eye
  • OS: left eye
  • OU: both eyes
  • QD: daily
  • Q 4 hr: every 4 hours
  • HS: at bedtime
  • ac: before meals
  • pc: after meals
  • prn: as needed

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Test your knowledge of pharmacology concepts with these flashcards from Chapter 3. Learn definitions related to drug therapy and the integrated medical sciences involved. Perfect for students needing a quick review of key pharmacological terms.

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