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What is pharmacology?
What is pharmacology?
Integrated medical science involving chemistry, biochemistry, anatomy, physiology, microbiology, and the study of drugs, their actions, dosage, therapeutic uses, and adverse effects.
What is drug therapy?
What is drug therapy?
Drug therapy is directly linked to the pathophysiology of a particular disease and includes sources such as natural sources from plants, animals, and microorganisms, as well as synthesized drugs.
What can drugs do?
What can drugs do?
Promote healing, cure disease, control or slow disease progress, prevent disease, alter neurotransmission, decrease the risk of complications, increase function and comfort, provide replacement therapy, and reduce excessive activity in the body.
What is pharmacodynamics?
What is pharmacodynamics?
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What is pharmacokinetics?
What is pharmacokinetics?
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What is pharmacotherapeutics?
What is pharmacotherapeutics?
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What is toxicology?
What is toxicology?
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What is pharmacy?
What is pharmacy?
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What does 'therapeutic' refer to in pharmacology?
What does 'therapeutic' refer to in pharmacology?
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What are drug classifications?
What are drug classifications?
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What are indications in pharmacology?
What are indications in pharmacology?
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What are contraindications?
What are contraindications?
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What are side effects?
What are side effects?
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What are adverse or toxic effects?
What are adverse or toxic effects?
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What does hypersensitivity refer to in relation to drugs?
What does hypersensitivity refer to in relation to drugs?
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What is an idiosyncratic reaction?
What is an idiosyncratic reaction?
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What does iatrogenic mean?
What does iatrogenic mean?
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What does teratogenic mean?
What does teratogenic mean?
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What are interactions in pharmacology?
What are interactions in pharmacology?
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What is synergism?
What is synergism?
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What is antagonism in pharmacology?
What is antagonism in pharmacology?
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What is potentiation?
What is potentiation?
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What is a dose in pharmacology?
What is a dose in pharmacology?
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How is a child's dose calculated?
How is a child's dose calculated?
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What is a loading dose?
What is a loading dose?
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What is frequency of dosing?
What is frequency of dosing?
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What is an optimum dosing schedule?
What is an optimum dosing schedule?
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What is a timing schedule in pharmacology?
What is a timing schedule in pharmacology?
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What factors affect blood levels of drugs?
What factors affect blood levels of drugs?
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How can drugs be administered?
How can drugs be administered?
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What is oral medication?
What is oral medication?
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What is sublingual administration?
What is sublingual administration?
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What is parenteral administration?
What is parenteral administration?
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What is inhalation in pharmacology?
What is inhalation in pharmacology?
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What is topical (transdermal) administration?
What is topical (transdermal) administration?
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What is drug absorption?
What is drug absorption?
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What is the role of receptors in drug action?
What is the role of receptors in drug action?
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What must a signed legal document for drug administration include?
What must a signed legal document for drug administration include?
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What is a generic name in pharmacology?
What is a generic name in pharmacology?
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What is a trade name?
What is a trade name?
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What is a chemical name?
What is a chemical name?
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What is drug regulation?
What is drug regulation?
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What does 'PO' stand for?
What does 'PO' stand for?
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What does 'IM' stand for?
What does 'IM' stand for?
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What does 'SQ' stand for?
What does 'SQ' stand for?
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What does 'BID' mean?
What does 'BID' mean?
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What does 'TID' mean?
What does 'TID' mean?
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What does 'QID' mean?
What does 'QID' mean?
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What does 'IV' stand for?
What does 'IV' stand for?
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What does 'OD' mean?
What does 'OD' mean?
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What does 'OS' mean?
What does 'OS' mean?
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What does 'OU' mean?
What does 'OU' mean?
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What does 'QD' mean?
What does 'QD' mean?
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What does 'Q 4 hr' mean?
What does 'Q 4 hr' mean?
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What does 'HS' stand for?
What does 'HS' stand for?
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What does 'ac' mean?
What does 'ac' mean?
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What does 'pc' mean?
What does 'pc' mean?
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What does 'prn' mean?
What does 'prn' mean?
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Study Notes
Pharmacology Overview
- Pharmacology integrates multiple medical sciences including chemistry, biochemistry, anatomy, physiology, and microbiology.
- It involves the study of drugs, including their actions, dosages, therapeutic uses, and adverse effects.
Drug Therapy
- Drug therapy is closely related to the disease's pathophysiology.
- Drugs can originate from natural sources like plants, animals, and microorganisms or be synthesized.
Drug Functions
- Drugs can promote healing (e.g., anti-inflammatories), cure diseases (e.g., antibacterials), control or slow disease progress (e.g., chemotherapy), and prevent diseases (e.g., vaccines).
- They can influence neurotransmission (e.g., antidepressants), decrease complication risks (e.g., anticoagulants), enhance function and comfort (e.g., analgesics), provide replacement therapy (e.g., insulin, estrogen), and reduce excessive bodily activity (e.g., proton pump inhibitors).
Pharmacodynamics & Pharmacokinetics
- Pharmacodynamics focuses on how drugs exert their effects.
- Pharmacokinetics studies the movement of drugs within the body based on the routes of administration.
Pharmacotherapeutics & Toxicology
- Pharmacotherapeutics involves using medications to prevent or treat diseases.
- Toxicology examines the body’s reactions to drugs, focusing on both harmful and beneficial effects.
Pharmacy Practice
- Pharmacy encompasses the preparation, dispensing, and management of drug use for safe and effective patient care.
Drug Classifications
- Drugs are classified based on their primary pharmacologic actions and effects.
Indications and Contraindications
- Indications refer to approved uses of drugs for specific conditions.
- Contraindications are specific scenarios where a drug should not be used.
Side Effects and Adverse Reactions
- Side effects are mild undesirable effects that may occur even at recommended doses.
- Adverse effects can be dangerous, cause significant harm, or even be life-threatening.
Unique Drug Reactions
- Hypersensitivity relates to allergic reactions; reactions may vary from mild to severe (anaphylaxis).
- Idiosyncratic reactions are unusual responses that differ from typical drug effects.
- Iatrogenic effects are negative outcomes associated with drug administration.
- Teratogenic effects refer to developmental defects caused by drug exposure to a fetus.
Drug Interactions
- Interactions modify drug effects when combined with other drugs.
- Synergism occurs when combined drugs produce a greater effect than the sum of individual effects.
- Antagonism results in diminished effects when drugs are combined.
- Potentiation happens when one drug enhances the effect of another.
Dosing Considerations
- Dosage is the amount of drug required for the desired effect, calculated by weight, measure, and frequency.
- Children's doses are determined primarily by weight, not age.
- A loading dose can be initially administered to quickly raise drug levels in the bloodstream.
- Frequency of dosing is critical to maintain effective blood levels without toxicity.
Routes of Drug Administration
- Oral medications are absorbed slowly and require processing by the liver.
- Sublingual medications are absorbed immediately under the tongue.
- Parenteral (injection) routes vary in absorption speed: subcutaneous (slow), intramuscular (moderate), and intravenous (immediate).
- Inhalation provides rapid absorption directly into the respiratory tract.
- Topical preparations can have varying speeds of absorption, with mucous membranes absorbing more quickly than skin.
Drug Absorption and Metabolism
- Drugs are generally metabolized in the liver and excreted by the kidneys, though some can be expelled through bile or feces.
- Barriers, such as the blood-brain barrier and placental barrier, can impede drug absorption.
Drug-Receptor Interaction
- Drug actions typically involve interactions with specific receptors.
- Drugs may directly stimulate or block receptors, influencing cellular functions and biochemical processes.
Legal and Regulatory Context
- Prescriptions must include patient and prescriber information, drug details, dosage, and usage instructions.
- Generic names identify drugs uniquely, while trade names are manufacturer-specific. Chemical names specify the drug's chemical structure.
- The FDA regulates drug production, labeling, and distribution; scheduled drugs are monitored for abuse potential, while OTC drugs are available without prescriptions.
Abbreviation Guide
- PO: orally by mouth
- IM: intramuscularly
- SQ: subcutaneously
- BID: twice a day
- TID: three times a day
- QID: four times a day
- IV: intravenous
- OD: right eye
- OS: left eye
- OU: both eyes
- QD: daily
- Q 4 hr: every 4 hours
- HS: at bedtime
- ac: before meals
- pc: after meals
- prn: as needed
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Description
Test your knowledge of pharmacology concepts with these flashcards from Chapter 3. Learn definitions related to drug therapy and the integrated medical sciences involved. Perfect for students needing a quick review of key pharmacological terms.