Podcast
Questions and Answers
How do most drugs pass through the placenta?
How do most drugs pass through the placenta?
- Endocytosis
- Active transport
- Facilitated diffusion
- Simple diffusion based on lipid solubility (correct)
How will the administration of drug B alter the effects of drug A?
How will the administration of drug B alter the effects of drug A?
- Diminish the therapeutic effects of drug A
- Have no impact on the effects of drug A
- Enhance the therapeutic and adverse effects of drug A (correct)
- Negate the effects of drug A
What is tissue redistribution particularly important for?
What is tissue redistribution particularly important for?
- Thiopental (correct)
- Enhancing drug absorption
- Facilitating drug excretion
- Increasing drug metabolism
What do agonists do in terms of tissue receptor sites?
What do agonists do in terms of tissue receptor sites?
If a drug has a weakly acidic pKa of 3.4, what can be inferred about its behavior?
If a drug has a weakly acidic pKa of 3.4, what can be inferred about its behavior?
What is the definition of ED50 for a drug?
What is the definition of ED50 for a drug?
Which route of administration provides the most predictable drug response?
Which route of administration provides the most predictable drug response?
What drug characteristic increases the tendency of a drug to cross cell membranes?
What drug characteristic increases the tendency of a drug to cross cell membranes?
If a drug has a pKa of 8.1 and is injected into tissue with a pH of 7.4, how much of the drug would be ionized in this tissue?
If a drug has a pKa of 8.1 and is injected into tissue with a pH of 7.4, how much of the drug would be ionized in this tissue?
What happens to a drug that is bound to plasma proteins?
What happens to a drug that is bound to plasma proteins?
If a patient receives a maximal dose of drug A followed by an average dose of drug B, what percentage of drug A is bound to plasma protein?
If a patient receives a maximal dose of drug A followed by an average dose of drug B, what percentage of drug A is bound to plasma protein?
