Pharmacology Chapter 1 Overview
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Questions and Answers

What is pharmacology?

The study of drugs (chemicals) that alter functions of living organisms.

What does pharmacotherapeutics refer to?

  • The branch of pharmacology that uses drugs to treat, prevent, and diagnose (correct)
  • The study of absorption and distribution of drugs
  • The study of drugs derived from herbal sources
  • The study of poisons and poisoning
  • What is pharmacodynamics?

    The study of biochemical and physiological effects of drugs and their mechanisms of action.

    What does pharmacokinetics study?

    <p>The absorption, distribution, biotransformation (metabolism), and excretion of drugs.</p> Signup and view all the answers

    What is pharmacognosy?

    <p>The study of drugs derived from herbal and other natural sources.</p> Signup and view all the answers

    Toxicology studies only the effects of beneficial drugs.

    <p>False</p> Signup and view all the answers

    The leaves of _____ are the source of Digoxin.

    <p>Digitalis Purpurea</p> Signup and view all the answers

    Which of the following is derived from animal sources?

    <p>Insulin</p> Signup and view all the answers

    Which mineral is used in the treatment of iron deficiency anemia?

    <p>Iron</p> Signup and view all the answers

    What is an orphan drug?

    <p>Drugs that have been discovered but are not financially viable and therefore have not been adopted by any drug company.</p> Signup and view all the answers

    What are illicit drugs?

    <p>Drugs used and/or distributed illegally</p> Signup and view all the answers

    Match the following FDA pregnancy categories with their descriptions:

    <p>Category A = No evidence of risk in the fetus Category B = Animal studies have not shown risk but no adequate studies in humans Category C = Animal studies have shown adverse effects but benefits may justify risks Category D = There is evidence of risk in humans, benefits could outweigh risks in serious conditions</p> Signup and view all the answers

    Study Notes

    Overview of Pharmacology

    • Pharmacology studies drugs that alter living organism functions.
    • Drug therapy, or pharmacotherapy, involves using drugs to prevent, diagnose, or treat diseases and symptoms.
    • Medications refer to drugs used for therapeutic purposes.

    Branches of Pharmacology

    • Pharmacotherapeutics: Focuses on using drugs to treat, prevent, and diagnose conditions.
    • Pharmacodynamics: Examines biochemical and physiological effects of drugs and their mechanisms of action.
    • Pharmacokinetics: Studies drug absorption, distribution, metabolism (biotransformation), and excretion.
    • Pharmacognosy: Investigates drugs derived from natural sources, including plants and herbs.
    • Toxicology: Analyzes poisons, their effects, and treatments for exposure to toxins.

    Sources of Drugs

    • Plants: Historically the oldest drug sources; all parts of plants are utilized (leaves, stems, bark, fruits, roots).
      • Example: Digitalis Purpurea provides cardiac glycosides (Digitoxin and Digoxin).
      • Example: Poppy (Papaver somniferum) is the source of morphine.
    • Animals:
      • Pancreas is a source of insulin for diabetes management.
      • Cod liver provides vitamins A and D.
      • Animal blood is essential for vaccine preparation.
    • Minerals:
      • Iron treats iron deficiency anemia.
      • Gold salts are used in rheumatoid arthritis treatment.
      • Iodine functions as an antiseptic and preventive measure.
    • Synthetic Chemicals: Clinically prepared drugs are derived from altering natural substances.
      • Examples include aspirin, antihistamines, oral antidiabetics, and chloroquine.
    • Microbiological Sources:
      • Penicillium notatum produces penicillin.
      • Actinobacteria yield Streptomycin and other aminoglycosides like gentamicin.

    Drug Classifications

    • Prescription Drugs: Requires a prescription by licensed health practitioners and includes a prescription legend on the label.
    • Non-Prescription Drugs: Known as over-the-counter (OTC) drugs, can be obtained without a prescription.
    • Investigational Drugs: Received FDA approval for human testing but may still be undergoing clinical trials.
    • Orphan Drugs: Discovered drugs lacking financial viability and not adopted by any pharmaceutical company.
    • Illicit Drugs: Illegal substances like heroin, marijuana, and meth that are used and distributed unlawfully.
    • FDA Pregnancy Categories: Classifies drugs based on their potential risks to fetuses.
      • Category A: No demonstrated risk in pregnant women; safe during all trimesters.
      • Category B: No risk shown in animal studies; insufficient human studies.
      • Category C: Adverse effects in animals; potential benefits may justify risks in pregnant women despite unclear human data.

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    Pharmacology_Introduction.pptx

    Description

    This quiz provides a comprehensive introduction to pharmacology, focusing on the fundamental concepts and definitions. It discusses the role of drug therapy in preventing, diagnosing, and treating diseases. Test your understanding of these essential principles of pharmacology.

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