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Pharmacology: Cardiac Medications

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Questions and Answers

What is the primary site of action for beta 1 selective blockers?

Lungs

Blood vessels

Pancreas

Heart (correct)

What is the consequence of giving non-selective beta blockers to patients with COPD or asthma?

BP increases

Pancreas releases insulin

Oxygen consumption decreases

Risk of exacerbation increases (correct)

What is the effect of metoprolol on the concentration of another drug?

It has no effect on the concentration of other drugs

It increases the concentration of beta-1 adrenergic blockers (correct)

It increases the concentration of angiotensin II

It decreases the concentration of beta-1 adrenergic blockers

What is the mechanism of action of beta 1 blockers on the heart?

It decreases the cardiac output and oxygen consumption Signup and view all the answers

What is the effect of nebivolol on the body?

It increases nitric oxide production leading to vasodilation Signup and view all the answers

When should metoprolol be administered in relation to meals?

1 hour before meals or 2 hours post meals Signup and view all the answers

What is the effect of verapamil on insulin?

Increases hypoglycemia Signup and view all the answers

What is the mechanism of action of Class III potassium channel blockers?

Acts directly on heart muscle cells to prolong repolarization and the refractory period Signup and view all the answers

What is a common side effect of potassium channel blockers?

Malaise and fatigue Signup and view all the answers

What is the effect of digoxin on potassium channel blockers?

Increases the effects of potassium channel blockers Signup and view all the answers

What is the mechanism of action of Class IV non-selective calcium channel blockers?

Blocks the movement of calcium ions across the cell membrane Signup and view all the answers

What is a common side effect of Class IV non-selective calcium channel blockers?

Bradycardia Signup and view all the answers

What is the primary mechanism of action of propranolol in the heart?

Competitively blocks beta-adrenergic receptors Signup and view all the answers

What is a major contraindication for the use of non-selective beta blockers?

Asthma Signup and view all the answers

What is the site of metabolism for propranolol?

Liver Signup and view all the answers

What is the effect of propranolol on the sympathetic nervous system?

Decreases its influence Signup and view all the answers

What are the possible adverse reactions to propranolol?

All of the above Signup and view all the answers

What is the normal conduction pathway in the heart?

SA node → AV node → Bundle of HIS → Purkinje fiber Signup and view all the answers