Podcast
Questions and Answers
What is John's Wort primarily indicated for?
What is John's Wort primarily indicated for?
- Severe insomnia
- Mild depression (correct)
- Severe anxiety
- Chronic pain relief
Which of the following is a common side effect of Valerian?
Which of the following is a common side effect of Valerian?
- Increased appetite
- Constipation
- Dry mouth
- Drowsiness (correct)
For which condition is John's Wort contraindicated?
For which condition is John's Wort contraindicated?
- Chronic fatigue
- Cocaine use (correct)
- Seasonal affective disorder
- Mild headaches
What is the primary neurotransmitter affected by Valerian?
What is the primary neurotransmitter affected by Valerian?
Which circumstance would contraindicate the use of Valerian?
Which circumstance would contraindicate the use of Valerian?
What is the primary focus of pharmacology?
What is the primary focus of pharmacology?
Which of the following is NOT a characteristic of an ideal drug?
Which of the following is NOT a characteristic of an ideal drug?
What defines a placebo in a clinical setting?
What defines a placebo in a clinical setting?
In pharmacotherapy, what does the term 'prototype' refer to?
In pharmacotherapy, what does the term 'prototype' refer to?
Which statement best describes pharmacotherapy?
Which statement best describes pharmacotherapy?
What is a characteristic of a brand name drug?
What is a characteristic of a brand name drug?
Which of the following is true about generic names of drugs?
Which of the following is true about generic names of drugs?
What aspect defines a drug's pharmacologic class?
What aspect defines a drug's pharmacologic class?
What is the purpose of Phase 1 in clinical trials?
What is the purpose of Phase 1 in clinical trials?
Which of the following best describes the therapeutic class of a drug?
Which of the following best describes the therapeutic class of a drug?
Which route of administration typically has the highest bioavailability?
Which route of administration typically has the highest bioavailability?
What is a primary advantage of enteral administration?
What is a primary advantage of enteral administration?
Which of the following is a disadvantage of parenteral administration?
Which of the following is a disadvantage of parenteral administration?
What is the purpose of a depot injection?
What is the purpose of a depot injection?
Which of the following describes a key disadvantage of topical administration?
Which of the following describes a key disadvantage of topical administration?
When applying a transdermal patch, what is a crucial step to ensure proper adhesion?
When applying a transdermal patch, what is a crucial step to ensure proper adhesion?
What is a common drawback of enteral drug administration compared to parenteral methods?
What is a common drawback of enteral drug administration compared to parenteral methods?
Which administration method can pose a risk of gastric irritation?
Which administration method can pose a risk of gastric irritation?
What is the primary characteristic of Schedule 1 drugs?
What is the primary characteristic of Schedule 1 drugs?
Which of the following is a requirement for Schedule 2 prescriptions?
Which of the following is a requirement for Schedule 2 prescriptions?
What distinguishes an Over-the-Counter (OTC) medication from a prescription drug?
What distinguishes an Over-the-Counter (OTC) medication from a prescription drug?
Which drug schedule allows for a maximum of five refills or prescription rewriting after six months?
Which drug schedule allows for a maximum of five refills or prescription rewriting after six months?
What is the main focus of pharmacokinetics in relation to medication?
What is the main focus of pharmacokinetics in relation to medication?
Which dosage form is known to have the highest bioavailability?
Which dosage form is known to have the highest bioavailability?
What does the term 'First Pass Effect' refer to?
What does the term 'First Pass Effect' refer to?
What is a common misconception about prescription drugs?
What is a common misconception about prescription drugs?
Which factor is NOT known to affect drug metabolism?
Which factor is NOT known to affect drug metabolism?
What is the primary route that experiences first pass metabolism?
What is the primary route that experiences first pass metabolism?
Which of the following statements about excretion is true?
Which of the following statements about excretion is true?
An agonist is characterized by which of the following actions?
An agonist is characterized by which of the following actions?
What does 'maintenance dose' refer to in pharmacology?
What does 'maintenance dose' refer to in pharmacology?
Which of the following describes 'trough level' in pharmacology?
Which of the following describes 'trough level' in pharmacology?
Which factor can slow down drug excretion from the body?
Which factor can slow down drug excretion from the body?
Which definition correctly describes 'onset of action'?
Which definition correctly describes 'onset of action'?
Flashcards
Pharmacology
Pharmacology
The study of drugs, their properties, effects, and interactions with living organisms.
Pharmacotherapy
Pharmacotherapy
The use of drugs to treat diseases.
Drug
Drug
Any substance that alters physiological function.
Placebo
Placebo
Signup and view all the flashcards
Prototype
Prototype
Signup and view all the flashcards
Brand Name
Brand Name
Signup and view all the flashcards
Generic Name
Generic Name
Signup and view all the flashcards
Chemical Name
Chemical Name
Signup and view all the flashcards
Therapeutic Class
Therapeutic Class
Signup and view all the flashcards
Pharmacologic Class
Pharmacologic Class
Signup and view all the flashcards
Drug Schedules
Drug Schedules
Signup and view all the flashcards
Schedule 1 Drug
Schedule 1 Drug
Signup and view all the flashcards
Schedule 2 Drug
Schedule 2 Drug
Signup and view all the flashcards
Schedule 3 Drug
Schedule 3 Drug
Signup and view all the flashcards
Schedule 4 Drug
Schedule 4 Drug
Signup and view all the flashcards
Prescription Drugs (Rx)
Prescription Drugs (Rx)
Signup and view all the flashcards
Over-the-Counter Drugs (OTC)
Over-the-Counter Drugs (OTC)
Signup and view all the flashcards
Pharmacokinetics
Pharmacokinetics
Signup and view all the flashcards
First-pass metabolism
First-pass metabolism
Signup and view all the flashcards
Parenteral administration
Parenteral administration
Signup and view all the flashcards
Depot injection
Depot injection
Signup and view all the flashcards
Topical administration
Topical administration
Signup and view all the flashcards
Transdermal patch application
Transdermal patch application
Signup and view all the flashcards
Enteral administration
Enteral administration
Signup and view all the flashcards
Bioavailability
Bioavailability
Signup and view all the flashcards
Drug elimination
Drug elimination
Signup and view all the flashcards
What is St. John's Wort?
What is St. John's Wort?
Signup and view all the flashcards
When is St. John's Wort contraindicated?
When is St. John's Wort contraindicated?
Signup and view all the flashcards
What is Valerian used for?
What is Valerian used for?
Signup and view all the flashcards
What are some potential side effects and contraindications of Valerian?
What are some potential side effects and contraindications of Valerian?
Signup and view all the flashcards
How does Valerian work?
How does Valerian work?
Signup and view all the flashcards
Drug Metabolism
Drug Metabolism
Signup and view all the flashcards
Drug Excretion
Drug Excretion
Signup and view all the flashcards
Agonist
Agonist
Signup and view all the flashcards
Partial Agonist
Partial Agonist
Signup and view all the flashcards
Antagonist
Antagonist
Signup and view all the flashcards
Loading Dose
Loading Dose
Signup and view all the flashcards
Maintenance Dose
Maintenance Dose
Signup and view all the flashcards
Study Notes
Introduction to Pharmacology
- Pharmacology: The study of drugs, their properties, effects, and interactions with living organisms.
- Pharmacotherapy: The treatment of diseases using drugs.
- Drug: Any substance that alters physiological function.
- Placebo: An inactive substance used as a control in experiments or therapies.
- Prototype: A standard or typical example of a drug used to compare other drugs in the same class.
- Ideal Drug: A medication that meets specific criteria for efficacy, safety, and convenience.
Characteristics of an Ideal Drug
- Effectively treats, prevents, or cures a condition.
- Rapid and predictable response at low doses.
- Quickly eliminated by the body after the therapeutic effect is produced.
- Can be taken infrequently or for a short time.
- Affordable and readily available.
- Convenient administration.
- No adverse effects.
- Does not interact with other medications or food.
Drug Naming
- Trade Name (Brand Name): Created by the drug company, often easier to remember and pronounce; must be approved by the FDA.
- Generic Name: A single name for a drug; first letter is lowercase; examples: sildenafil, acetaminophen, ibuprofen, atorvastatin
Drug Schedules
- Schedule 1: All non-research use is illegal; highest potential for abuse (Heroin, LSD, MDMA).
- Schedule 2: Accepted medical use but high potential for abuse (Oxycodone, Morphine).
Legal Classification of Drugs
- Prescription Drugs (Rx): Available only with a prescription; typically require training/skill to administer.
- Over-the-Counter Drugs (OTC): Available to the general population without a prescription.
Drug Development and Approval
- Laboratory Research, Pre-clinical Research, Clinical Trials (Phase 1 – Safety, Phase 2 – Effectiveness, Phase 3 – Patient Variability & Drug Interactions), Government Review, Post-Marketing Surveillance.
Pharmacokinetics
- Bioavailability: The amount of a drug that reaches the bloodstream after administration.
- First-Pass Metabolism: When a drug is absorbed through the intestines, it passes through the liver before entering general circulation. Some of the drug may be broken down, reducing bioavailability.
Routes of Administration
- Enteral: Oral (tablet, capsule, controlled release), sublingual, buccal, nasogastric tube, rectal.
- Parenteral: Intravenous, intramuscular, subcutaneous, intradermal, epidural, transdermal.
- Topical: Transdermal, eye, ear, vaginal.
- Inhalation: Vaporization, gas inhalation, nebulization.
Factors Affecting Absorption
- Administration route
- Drug solubility
- pH levels
- Presence of food
Drug Toxicity
- Teratogenicity: Causes harm to a developing fetus.
- Nephrotoxicity: Damage to the kidneys.
- Hepatotoxicity: Damage to the liver.
- Neurotoxicity: Damage to the brain or nerves.
- Dermatologic toxicity: Damage to the skin.
- Ototoxicity: Damage to the ear.
- Musculoskeletal toxicity: Damage to muscles or tendons.
- Bone marrow suppression: Impaired production of blood cells.
- Cardiotoxicity: Damage to the heart
Drug Interactions
- Drugs interacting with other drugs, foods, or other substances.
Medication Errors
- Strategies to reduce medication errors involve up-to-date knowledge, sticking to what's known, scanning and confirming information, consulting interdisciplinary teams, writing out orders, not having look-a-likes and sound-a-likes stored together.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.