Foundations of Clinical Pharmacology: W1 Drug Classifications Quiz

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Questions and Answers

Which term refers to the ability of a drug to cause defects in a developing fetus?

  • Teratogenicity (correct)
  • Polypharmacy
  • Drug Safety
  • Pharmacokinetics

In pharmacokinetics, which factor relates to the percentage of the drug reaching systemic circulation chemically unchanged?

  • Bioavailability (correct)
  • Carrier molecule
  • Stomach contents
  • Drug solubility

Which factor is crucial in considering drug dosages for individuals with liver disease?

  • Liver disease cumulative drug effect (correct)
  • +Age
  • Hx allergies/drug reactions
  • Polypharmacy

Which route of drug administration typically provides the fastest speed of drug action?

<p>IV (D)</p> Signup and view all the answers

What is the term used to define the range between the minimum effective dose and the minimum toxic dose of a drug?

<p>Therapeutic margin (B)</p> Signup and view all the answers

What is the primary route of drug excretion?

<p>Renal excretion (C)</p> Signup and view all the answers

Which process is responsible for the conversion of a drug into inactive compounds in the liver?

<p>Metabolism (B)</p> Signup and view all the answers

Why is it important for protein molecules to release drugs bound to them?

<p>To enhance drug absorption into tissues (A)</p> Signup and view all the answers

What is the function of an antagonist drug?

<p>To bind with a receptor and prevent the action of an agonist (C)</p> Signup and view all the answers

Which system is responsible for metabolizing approximately 90% of drugs?

<p>CYP 450 System (B)</p> Signup and view all the answers

What integumentary symptom is characterized by swelling under the skin instead of on the surface?

<p>Angioedema (A)</p> Signup and view all the answers

Which of the following is NOT a respiratory symptom of anaphylactic shock?

<p>Tachycardia (C)</p> Signup and view all the answers

What type of reaction is associated with microbial die-off induced by medication?

<p>Herxheimer Reaction (B)</p> Signup and view all the answers

Which drug-herb interactions affect pharmacokinetics by influencing stomach pH?

<p>Hai Ge Fen and Hai Piao Xiao (B)</p> Signup and view all the answers

What is a common gastrointestinal symptom associated with anaphylactic shock?

<p>Abdominal pain (B)</p> Signup and view all the answers

What is the significance of half-life in drug administration?

<p>Indicates the time required to eliminate 50% of the drug from the body (C)</p> Signup and view all the answers

How does liver or kidney disease affect the half-life of a drug?

<p>Increases the half-life (D)</p> Signup and view all the answers

What is the primary measure of drug safety known as?

<p>Therapeutic Margin (C)</p> Signup and view all the answers

Which factor affects the therapeutic margin of a drug?

<p>Dietary changes and medication interactions (C)</p> Signup and view all the answers

What is a crucial consideration when combining Chinese medicinals with prescription medications?

<p>Communicate clearly with healthcare providers (D)</p> Signup and view all the answers

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