Foundations of Clinical Pharmacology: W1 Drug Classifications Quiz

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Which term refers to the ability of a drug to cause defects in a developing fetus?

Teratogenicity (correct)

Polypharmacy

Drug Safety

Pharmacokinetics

In pharmacokinetics, which factor relates to the percentage of the drug reaching systemic circulation chemically unchanged?

Bioavailability (correct)

Carrier molecule

Stomach contents

Drug solubility

Which factor is crucial in considering drug dosages for individuals with liver disease?

Liver disease cumulative drug effect (correct)

+Age

Hx allergies/drug reactions

Polypharmacy

Which route of drug administration typically provides the fastest speed of drug action?

IV Signup and view all the answers

What is the term used to define the range between the minimum effective dose and the minimum toxic dose of a drug?

Therapeutic margin Signup and view all the answers

What is the primary route of drug excretion?

Renal excretion Signup and view all the answers

Which process is responsible for the conversion of a drug into inactive compounds in the liver?

Metabolism Signup and view all the answers

Why is it important for protein molecules to release drugs bound to them?

To enhance drug absorption into tissues Signup and view all the answers

What is the function of an antagonist drug?

To bind with a receptor and prevent the action of an agonist Signup and view all the answers

Which system is responsible for metabolizing approximately 90% of drugs?

CYP 450 System Signup and view all the answers

What integumentary symptom is characterized by swelling under the skin instead of on the surface?

Angioedema Signup and view all the answers

Which of the following is NOT a respiratory symptom of anaphylactic shock?

Tachycardia Signup and view all the answers

What type of reaction is associated with microbial die-off induced by medication?

Herxheimer Reaction Signup and view all the answers

Which drug-herb interactions affect pharmacokinetics by influencing stomach pH?

Hai Ge Fen and Hai Piao Xiao Signup and view all the answers

What is a common gastrointestinal symptom associated with anaphylactic shock?

Abdominal pain Signup and view all the answers

What is the significance of half-life in drug administration?

Indicates the time required to eliminate 50% of the drug from the body Signup and view all the answers

How does liver or kidney disease affect the half-life of a drug?

Increases the half-life Signup and view all the answers

What is the primary measure of drug safety known as?

Therapeutic Margin Signup and view all the answers

Which factor affects the therapeutic margin of a drug?

Dietary changes and medication interactions Signup and view all the answers

What is a crucial consideration when combining Chinese medicinals with prescription medications?

Communicate clearly with healthcare providers Signup and view all the answers