31 Questions
What is the biggest use of Bacitracin?
Treating blepharitis
In what form is Bacitracin available in the US?
Ointment
What is the spectrum of activity for Bacitracin?
Gram-positive
What is the recommendation for using Vancomycin during pregnancy according to Epocrates for injection?
Avoid during the 1st and 2nd trimesters
What is a consideration for the use of Vancomycin during pregnancy according to Drugs.com?
Highly toxic
Which adverse effect is associated with the use of Vancomycin?
Neutropenia
What type of drug is Bacitracin?
Antibacterial affecting cell wall synthesis
What is the most common observed effect of vancomycin-induced ototoxicity?
Temporary but can be irreversible hearing loss
What is the unpredictable nature of ototoxicity associated with vancomycin?
It may occur even after discontinuing the drug
Which antibiotic causes an imbalance in osmotic gradient between the internal aspect of bacteria and the external environment, leading to disruption of the bacterial cell membrane?
Polymyxin B
What is the clinical use of Polymyxin B?
Treatment of bacterial conjunctival and lid infections
What type of bacteria is Polymyxin B especially effective against?
Gram negative bacteria
Which antibiotic can lead to disruption of the cell’s osmotic integrity by interacting with the bacterial cell membrane?
Polymyxin B
In what form is hearing loss commonly observed with vancomycin-induced ototoxicity?
Sudden and unilateral
Which characteristic best describes the effect of vancomycin-induced ototoxicity?
Inconsistent onset and sometimes irreversible hearing loss
What is the primary mechanism of action of tetracycline?
Inhibition of protein synthesis
For which of the following conditions is tetracycline NOT typically used?
Amebiasis
What is the spectrum of activity of tetracycline?
Both gram-positive and gram-negative bacteria
Which of the following is a resistance developed towards tetracycline?
Staphylococcus aureus
In what form can tetracycline be administered for Chlamydia infection?
Oral
Which activity does tetracycline specifically decrease, contributing to its effectiveness in certain conditions?
Lipase production
Tetracycline is NOT typically used for the treatment of which condition?
Glaucoma
What type of activity does tetracycline have in relation to systemic effects on the body?
Anti-inflammatory
Which antibiotic interacts with the bacterial cell membrane and disrupts the cell's osmotic integrity?
Polymyxin B
Which antibiotic is commonly used in combination with neomycin and polymyxin B in a product known as Neosporin?
Gramicidin
Which category of antibiotics includes drugs like gentamicin and tobramycin that are commonly used in ocular conditions?
Aminoglycosides
Which antibiotic is known for its inhibition of bacterial protein synthesis and is available in forms like tetracycline, doxycycline, and minocycline?
Tetracycline
Which antibiotic is effective against gram-negative bacteria and is often used in combination with other antibiotics such as neomycin?
Polymyxin B
Which antibiotic has both bactericidal and some static activity and is more effective against gram-positive bacteria?
Gramicidin
Which antibiotic is associated with potential use during pregnancy and breastfeeding?
Neomycin
Which category of antibiotics includes azithromycin, clarithromycin, and erythromycin?
Macrolides
Test your knowledge of antibiotics affecting the cytoplasmic membrane with this quiz. Topics include Gramicidin, interactions with bacterial cell membrane, disruption of cell’s osmotic integrity, bactericidal and static activity, Gram positive bacteria, and combination antibiotics like Neosporin.
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