Pharmacology: Antibiotics Affecting Cytoplasmic Membrane Quiz
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Questions and Answers

What is the biggest use of Bacitracin?

  • Treating skin infections
  • Treating blepharitis (correct)
  • Treating urinary tract infections
  • Treating respiratory infections

    • In what form is Bacitracin available in the US?

  • Injection
  • Oral solution
  • Capsule
  • Ointment (correct)

    • What is the spectrum of activity for Bacitracin?

  • Antifungal
  • Gram-positive (correct)
  • Gram-negative
  • Antiviral

    • What is the recommendation for using Vancomycin during pregnancy according to Epocrates for injection?

    <p>Avoid during the 1st and 2nd trimesters</p> Signup and view all the answers

    What is a consideration for the use of Vancomycin during pregnancy according to Drugs.com?

    <p>Highly toxic</p> Signup and view all the answers

    Which adverse effect is associated with the use of Vancomycin?

    <p>Neutropenia</p> Signup and view all the answers

    What type of drug is Bacitracin?

    <p>Antibacterial affecting cell wall synthesis</p> Signup and view all the answers

    What is the most common observed effect of vancomycin-induced ototoxicity?

    <p>Temporary but can be irreversible hearing loss</p> Signup and view all the answers

    What is the unpredictable nature of ototoxicity associated with vancomycin?

    <p>It may occur even after discontinuing the drug</p> Signup and view all the answers

    Which antibiotic causes an imbalance in osmotic gradient between the internal aspect of bacteria and the external environment, leading to disruption of the bacterial cell membrane?

    <p>Polymyxin B</p> Signup and view all the answers

    What is the clinical use of Polymyxin B?

    <p>Treatment of bacterial conjunctival and lid infections</p> Signup and view all the answers

    What type of bacteria is Polymyxin B especially effective against?

    <p>Gram negative bacteria</p> Signup and view all the answers

    Which antibiotic can lead to disruption of the cell’s osmotic integrity by interacting with the bacterial cell membrane?

    <p>Polymyxin B</p> Signup and view all the answers

    In what form is hearing loss commonly observed with vancomycin-induced ototoxicity?

    <p>Sudden and unilateral</p> Signup and view all the answers

    Which characteristic best describes the effect of vancomycin-induced ototoxicity?

    <p>Inconsistent onset and sometimes irreversible hearing loss</p> Signup and view all the answers

    What is the primary mechanism of action of tetracycline?

    <p>Inhibition of protein synthesis</p> Signup and view all the answers

    For which of the following conditions is tetracycline NOT typically used?

    <p>Amebiasis</p> Signup and view all the answers

    What is the spectrum of activity of tetracycline?

    <p>Both gram-positive and gram-negative bacteria</p> Signup and view all the answers

    Which of the following is a resistance developed towards tetracycline?

    <p>Staphylococcus aureus</p> Signup and view all the answers

    In what form can tetracycline be administered for Chlamydia infection?

    <p>Oral</p> Signup and view all the answers

    Which activity does tetracycline specifically decrease, contributing to its effectiveness in certain conditions?

    <p>Lipase production</p> Signup and view all the answers

    Tetracycline is NOT typically used for the treatment of which condition?

    <p>Glaucoma</p> Signup and view all the answers

    What type of activity does tetracycline have in relation to systemic effects on the body?

    <p>Anti-inflammatory</p> Signup and view all the answers

    Which antibiotic interacts with the bacterial cell membrane and disrupts the cell's osmotic integrity?

    <p>Polymyxin B</p> Signup and view all the answers

    Which antibiotic is commonly used in combination with neomycin and polymyxin B in a product known as Neosporin?

    <p>Gramicidin</p> Signup and view all the answers

    Which category of antibiotics includes drugs like gentamicin and tobramycin that are commonly used in ocular conditions?

    <p>Aminoglycosides</p> Signup and view all the answers

    Which antibiotic is known for its inhibition of bacterial protein synthesis and is available in forms like tetracycline, doxycycline, and minocycline?

    <p>Tetracycline</p> Signup and view all the answers

    Which antibiotic is effective against gram-negative bacteria and is often used in combination with other antibiotics such as neomycin?

    <p>Polymyxin B</p> Signup and view all the answers

    Which antibiotic has both bactericidal and some static activity and is more effective against gram-positive bacteria?

    <p>Gramicidin</p> Signup and view all the answers

    Which antibiotic is associated with potential use during pregnancy and breastfeeding?

    <p>Neomycin</p> Signup and view all the answers

    Which category of antibiotics includes azithromycin, clarithromycin, and erythromycin?

    <p>Macrolides</p> Signup and view all the answers

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