Pharmacology and Perfusion Concepts
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Questions and Answers

Which medication is a Proton Pump Inhibitor used for managing Peptic Ulcer Disease?

  • ondansetron
  • methotrexate
  • omeprazole (correct)
  • prednisone

What type of medication is hydrocortisone classified as?

  • Nonbiologic DMARD
  • Glucocorticoid (correct)
  • Serotonin agonist
  • Beta Blocker

Which medication is primarily used as a non-biologic DMARD for arthritis treatment?

  • prednisone
  • omeprazole
  • methotrexate (correct)
  • levothyroxine

What condition is a glucocorticoid such as prednisone primarily indicated for?

<p>Rheumatoid Arthritis (A)</p> Signup and view all the answers

Which medication is an opioid that can be used to treat diarrhea?

<p>diphenoxylate with atropine (D)</p> Signup and view all the answers

What is the correct definition of pharmacodynamics?

<p>The biochemical changes in the body as a result of medication (A)</p> Signup and view all the answers

Which term describes medications that bind with receptors to produce a greater-than-typical response?

<p>Agonists (A)</p> Signup and view all the answers

What occurs during the metabolism of a medication?

<p>Medication becomes more or less potent (A)</p> Signup and view all the answers

What does the term duration refer to in pharmacology?

<p>Length of time therapeutic effects last without additional doses (D)</p> Signup and view all the answers

What is central perfusion primarily affected by?

<p>Reduced cardiac output (A)</p> Signup and view all the answers

Which condition could potentially result from severe central perfusion issues if untreated?

<p>Ischemia and cell death (B)</p> Signup and view all the answers

What describes the flow of blood through arteries and capillaries delivering nutrients and oxygen?

<p>Perfusion (C)</p> Signup and view all the answers

What is the recommended position for elevating the legs to reduce swelling?

<p>At heart level (C)</p> Signup and view all the answers

Which of the following is NOT a recommendation for client education to manage blood flow?

<p>Promote vasocontraction (C)</p> Signup and view all the answers

At what blood pressure reading is hypertension identified?

<p>130/80 (C)</p> Signup and view all the answers

Which clinical manifestation may indicate primary hypertension?

<p>Facial flush (A)</p> Signup and view all the answers

What type of medication is Metoprolol classified as?

<p>Beta blocker (C)</p> Signup and view all the answers

Which dietary approach is recommended for managing hypertension?

<p>DASH diet (A)</p> Signup and view all the answers

What condition is characterized by excess intake of fluids leading to abnormal retention?

<p>Hypervolemia (C)</p> Signup and view all the answers

Fluid volume deficit (hypovolemia) can result in which lab finding?

<p>Increased lab values due to low fluids (C)</p> Signup and view all the answers

What sodium level is indicative of hypernatremia?

<blockquote> <p>145 (C)</p> </blockquote> Signup and view all the answers

Which precaution is necessary when monitoring a patient with hypernatremia?

<p>Seizure precautions (C)</p> Signup and view all the answers

What symptom is associated with arterial peripheral vascular disease?

<p>Burning pain in the legs during exercise (D)</p> Signup and view all the answers

Which intervention helps to promote blood flow in patients with ischemia?

<p>Use of vasodilators (B)</p> Signup and view all the answers

How does rest impact the symptoms of intermittent claudication?

<p>Pain is relieved upon stopping activity (D)</p> Signup and view all the answers

What characteristic is exhibited by venous insufficiency?

<p>Thick, tough skin with brownish color (B)</p> Signup and view all the answers

What position should a patient with venous insufficiency ideally assume to alleviate symptoms?

<p>Legs elevated (C)</p> Signup and view all the answers

In which part of the body are varicose veins most commonly observed?

<p>Lower leg (B)</p> Signup and view all the answers

Which of the following is a common characteristic of arterial disease lesions?

<p>Punched out appearance, pale/pink color (A)</p> Signup and view all the answers

Which risk factor can be modified to help reduce peripheral vascular disease symptoms?

<p>Smoking cessation (C)</p> Signup and view all the answers

What does the term 'dependent position' refer to in the context of arterial disease?

<p>Dangling legs down (D)</p> Signup and view all the answers

What is the primary treatment for a hypoglycemic client who is unconscious?

<p>Administer glucagon (A)</p> Signup and view all the answers

Which of the following insulins is considered rapid-acting?

<p>Lispro (B)</p> Signup and view all the answers

Which condition is characterized by blood glucose levels higher than normal without ketoacidosis?

<p>Hyperglycemic Hyperosmolar Syndrome (HHS) (D)</p> Signup and view all the answers

What is the priority nursing intervention for a patient with hyperthyroidism?

<p>Administer antithyroid medication (A)</p> Signup and view all the answers

Which of the following is a common manifestation of hypoglycemia?

<p>Tachycardia (C)</p> Signup and view all the answers

What lifestyle modification is generally recommended for infection prevention?

<p>Practice good hygiene (D)</p> Signup and view all the answers

Which medication is considered a stimulant laxative for treating constipation?

<p>Bisacodyl (C)</p> Signup and view all the answers

When assessing for systemic versus local infection, which sign would indicate a systemic infection?

<p>Fever (C)</p> Signup and view all the answers

What is the role of metformin in diabetes management?

<p>It increases insulin sensitivity. (C)</p> Signup and view all the answers

Standard precautions should be maintained to prevent which of the following?

<p>All infections (B)</p> Signup and view all the answers

Flashcards

Pharmacokinetics

The movement of a medication from the administration site to the circulatory system.

Pharmacodynamics

The biochemical changes that occur in the body after a medication is administered.

Agonist

A medication that binds to a receptor and produces a stronger response than usual.

Antagonist

A medication that binds to a receptor and either blocks or reduces a response.

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Central Perfusion

Reduced cardiac output leading to decreased oxygenated blood reaching body tissues.

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Local Perfusion

Impaired blood flow to specific tissues due to vessel issues.

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Medication Absorption

The movement of medicine from the site of administration to the bloodstream.

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Peripheral Arterial Disease (PAD)

A condition affecting the arteries, reducing blood flow to the extremities.

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Intermittent Claudication

Leg pain/cramping during exercise, relieved by rest.

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Rest Pain

Sharp pain in the legs while resting, especially at night.

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Peripheral Venous Disease

Affects veins, blood flow towards the heart.

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VTE

Blood clot in a vein, often in the legs.

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Venous Insufficiency

Damaged valves in leg veins leading to poor blood flow.

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Varicose Veins

Enlarged, twisted veins, often in the legs.

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Edema

Swelling caused by fluid buildup, often in the legs.

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Positioning for PAD/VD

Avoid crossing legs, and don't wear restrictive clothing to help blood circulation.

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Elevating legs for swelling

Raising legs below heart level to reduce swelling, avoiding slowing arterial blood flow to feet.

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High blood pressure stages

Stage 1 (130-139/80-89 mmHg) and Stage 2 (140/90 mmHg or higher).

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Beta-blocker for hypertension

Medication like metoprolol that lowers blood pressure.

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DASH diet

Dietary plan to control hypertension, promoting heart health.

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Fluid volume excess (hypervolemia)

Excessive fluid intake, leading to abnormal fluid retention.

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Fluid volume deficit (hypovolemia)

Abnormal fluid loss or insufficient intake, reduced blood volume.

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Hypernatremia

High sodium levels in the blood (>145 mEq/L).

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Fluid volume excess treatment

Management involving reducing fluid intake and medications.

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Fluid volume deficit treatment

Management involving increasing fluid intake and solutions.

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Hypertension symptoms

Potentially includes headaches, flushing, dizziness, fainting.

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Peptic Ulcer Disease

A condition where sores develop in the lining of the stomach or duodenum, often caused by H. pylori infection or NSAID use.

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Proton Pump Inhibitors (PPIs)

Medications that block the production of stomach acid, used to treat ulcers and GERD.

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What are the clinical manifestations of Osteoarthritis?

Joint pain, stiffness, swelling, decreased range of motion, crepitus (grating sound), and bone spurs.

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What are the clinical manifestations of Rheumatoid Arthritis?

Symmetrical joint pain and swelling, morning stiffness, fatigue, decreased mobility, and joint deformities.

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What are some non-pharmacological interventions for Osteo and Rheumatoid Arthritis?

Weight management, regular exercise, assistive devices, heat therapy, and joint protection techniques.

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Diabetes Types Causes

Causes of different types of diabetes vary, but often include genetic predisposition, lifestyle factors (diet and exercise), and immune system issues.

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Hyperglycemia Clinical Manifestations

High blood sugar; symptoms include increased thirst, frequent urination, blurred vision, and fatigue.

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Hypoglycemia Clinical Manifestations

Low blood sugar; symptoms include shakiness, sweating, confusion, or difficulty speaking.

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Rule of 15 for Hypoglycemia

Treat low blood sugar with 15g of fast-acting carbohydrates, recheck blood sugar, and repeat if needed.

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Unconscious Hypoglycemia Treatment

Administer glucagon injection; call for emergency medical assistance.

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Thyroid Replacement Medication

Medication used to treat hypothyroidism, replacing the lacking thyroid hormone.

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Constipation Pharmacological Treatment

Medication to treat constipation, varies depending on the cause.

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Diarrhea Pharmacological Treatment

Medication to treat diarrhea, often focusing on reducing bowel movements' frequency.

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Infection Prevention Techniques

Methods to prevent spread of infections, including hand hygiene, vaccinations, and appropriate isolation techniques.

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Study Notes

Pharmacology (1)

  • Pharmacokinetics: Movement of a medication from administration site to the circulatory system. Includes absorption, distribution, metabolism, and excretion.
  • Pharmacodynamics: Biochemical changes in the body caused by a medication.
  • Agonists: Medications binding to a receptor, causing a greater-than-typical response.
  • Antagonists: Medications binding to a receptor, either blocking a response or causing a less-than-typical response. Can be competitive or non-competitive.

Perfusion (1)

  • Definition: Blood flow through arteries and capillaries, delivering nutrients and oxygen to cells.
  • Peripheral Arterial Disease (PAD): Reduced cardiac output leads to reduced oxygen delivery to tissues; localized vessel blockage/inadequacy; symptoms include pain, cramping, and coolness. Risk factors include smoking, hypertension, diabetes.
  • Peripheral Venous Disease: Vessel damage or poor venous return. Symptoms include pain, swelling, and skin changes. Risk factors include obesity, prolonged standing.
  • Causes of Impaired Perfusion: Systemic (reduced cardiac output); Local (vessel blockage, etc.)
  • Nursing Interventions: Vasodilators, vascular interventions (to open narrowed vessels), risk factor reduction.

Fluid and Electrolytes (3)

  • Fluid Volume Excess (Hypervolemia): Excessive fluid intake or abnormal fluid retention; can lead to swelling. Lab values may show a decreased level.
  • Fluid Volume Deficit (Hypovolemia): Inadequate fluid intake, excessive fluid loss or plasma shifting. Lab values may show increased levels.
  • Sodium Imbalances: High sodium (hypernatremia) due to inadequate fluid intake or excessive sodium; Low sodium (hyponatremia) due to decreased sodium intake or excess water loss.
  • Potassium Imbalances: High potassium (hyperkalemia) may result from kidney failure, or medications; Low potassium (hypokalemia), may be caused by some medications.
  • Fluid Balance Management: Accurately measuring and recording fluid intake and output is crucial.

Pain (4)

  • Classifications & Types: Acute, chronic, breakthrough.
  • Nursing Assessment & Evaluation: PQRSTU (Provoking/Palliative Factors, Quality, Region, Severity, Timing, Understand patient's experience); Pain scales, and other subjective data may be collected.
  • Nursing Interventions: Pharmacological (NSAIDs, opioids, etc.) and non-pharmacological (techniques like relaxation, guided imagery).

Other Topics (5-13)

  • The remaining sections cover various topics like gas exchange, glucose regulation, hormonal regulation, infections, elimination, nutrition, tissue integrity, inflammation, and specific disorders like osteoporosis, Cushing's, and Addison's disease.
  • Each section details causes, clinical manifestations, priority nursing assessments, and interventions for those topics.

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Description

This quiz covers essential concepts in pharmacology, including pharmacokinetics, pharmacodynamics, agonists, and antagonists. It also explores definitions and conditions associated with perfusion, such as Peripheral Arterial Disease and Peripheral Venous Disease. Test your understanding of how medications interact with the body and the implications for blood flow and oxygen delivery.

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