Pharmacology and Liver Diseases
16 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the key factor that determines the severity and site of action of a drug?

  • Patient's age
  • Patient's body weight
  • Concentration of the drug in the plasma (correct)
  • Route of administration

    • How does the effect of a liposoluble drug differ between obese and thin people when the drug is discontinued?

  • The effect lasts longer in thin people and disappears quickly in obese people.
  • The effect lasts the same duration in both obese and thin people.
  • The effect lasts longer in obese people and disappears quickly in thin people. (correct)
  • The effect disappears immediately in both obese and thin people.

    • How does drug elimination differ between newborns, infants, and children?

  • Newborns, infants, and children all have similar rates of drug elimination.
  • Infants have the highest rate of drug elimination, while newborns and children have lower rates.
  • Newborns have the highest rate of drug elimination, while infants and children have lower rates. (correct)
  • Children have the highest rate of drug elimination, while newborns and infants have lower rates.

    • How should the dose of a drug be adjusted for patients with different body weights?

    <p>Adjust the dose based on the patient's body surface area.</p> Signup and view all the answers

    How does the rate of drug elimination differ between men and women?

    <p>The rate of drug elimination depends on the specific drug and its metabolism, not on gender.</p> Signup and view all the answers

    How does drug distribution differ between newborns, infants, and children?

    <p>Newborns have the highest total body fluid and extracellular fluid volumes, while infants and children have lower volumes.</p> Signup and view all the answers

    What is the primary reason for the adjustment of plasma protein and plasma-fetus protein binding in pregnant women?

    <p>Increased albumin levels</p> Signup and view all the answers

    What is the primary mechanism by which antihypertensive drugs can reduce their own effectiveness over time?

    <p>Increased water and salt retention</p> Signup and view all the answers

    What is the primary reason for the difference in drug response between individuals?

    <p>Biological variability</p> Signup and view all the answers

    What is the primary difference between R (right) and S (left) isomers of a drug?

    <p>Both a and b</p> Signup and view all the answers

    What is the key characteristic of tolerance that distinguishes it from tachyphylaxis and desensitization?

    <p>All of the above</p> Signup and view all the answers

    What is the primary mechanism behind cross-tolerance between drugs in the same pharmacological group?

    <p>Shared pharmacodynamic properties</p> Signup and view all the answers

    Which of the following is the most likely reason for the increased severity of drug effects in obese individuals compared to thin individuals when the drug is discontinued?

    <p>Decreased drug elimination in obese individuals</p> Signup and view all the answers

    How does drug elimination differ between newborns, infants, and children?

    <p>The text does not provide information about differences in drug elimination between these age groups</p> Signup and view all the answers

    How does the effect of a liposoluble drug differ between obese and thin people when the drug is discontinued?

    <p>The text does not provide information about this</p> Signup and view all the answers

    What is the key factor that determines the severity and site of action of a drug?

    <p>The text does not provide information about this</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser