Pharmacological Control of Reproduction in Males

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Questions and Answers

Which hormone is responsible for the negative feedback effect on the hypothalamus and pituitary gland in the male reproductive system?

  • Oestrogen
  • Progesterone
  • Testosterone (correct)
  • GnRH

What effect does adding progesterone to the male reproductive system have?

  • Increases testosterone production
  • Reduces secretion of GnRH (correct)
  • Activates the gonad
  • Stimulates follicle production

What is the main effect of Durateston on the male reproductive system?

  • Reduces secretion of GnRH
  • Increases testosterone production (correct)
  • Activates the gonad
  • Stimulates follicle production

What is the primary function of large negative feedback loops in the control of male reproduction?

<p>Reduce secretion of GnRH (D)</p> Signup and view all the answers

What hormone is responsible for the regulation of the hypothalamus and pituitary gland in the male reproductive system?

<p>Testosterone (C)</p> Signup and view all the answers

What happens to the testicles when there is no activation of the gonad in the male reproductive system?

<p>Decrease in size (D)</p> Signup and view all the answers

What effect does adding exogenous oestrogen to the male reproductive system have?

<p>Reduces secretion of GnRH (B)</p> Signup and view all the answers

What is the role of GnRH in the male reproductive system?

<p>Activates the gonad (D)</p> Signup and view all the answers

What is the main effect of progestogens on testosterone levels in males?

<p>Decrease testosterone due to negative feedback effect (A)</p> Signup and view all the answers

Why do we tend not to use oestrogens in treating peri-anal adenomas in males?

<p>They cause bone marrow suppression (A)</p> Signup and view all the answers

What is the main effect of a depot preparation of deslorelin (GnRH agonist) on male sex behaviors?

<p>Initial stimulation followed by receptor down-regulation (A)</p> Signup and view all the answers

What is the main use of hCG (LH-like) in males?

<p>To confirm the presence of testicular tissue (A)</p> Signup and view all the answers

Which of the following drugs is commonly used to reduce the size of peri-anal adenomas in males?

<p>Progestogens (A)</p> Signup and view all the answers

What is the effect of giving GnRH exogenous repeated doses in males?

<p>Stimulation of release followed by receptor down-regulation (A)</p> Signup and view all the answers

Which of the following drugs can be used to test for the presence of testicular tissue in males?

<p>hCG (A)</p> Signup and view all the answers

What is the main effect of giving FSH or LH in males to improve semen quality?

<p>Limited impact on semen quality (A)</p> Signup and view all the answers

Which of the following drugs has a similar activity to LH in males?

<p>hCG (B)</p> Signup and view all the answers

What is the role of negative feedback loops in the pharmacological control of reproduction in males?

<p>Negative feedback loops effectively regulate the secretion of hormones in the male reproductive system.</p> Signup and view all the answers

How do follicles in the ovary contribute to the regulation of reproduction in females?

<p>Follicles in the ovary produce estrogen, which plays a role in the regulation of reproduction in females.</p> Signup and view all the answers

What hormone is produced by the corpus luteum and how does it affect the reproductive system?

<p>The corpus luteum produces progesterone, which plays a role in regulating the reproductive system.</p> Signup and view all the answers

How does the addition of progesterone to the reproductive system affect the secretion of GnRH, FSH, and LH?

<p>The addition of progesterone has a negative feedback effect, reducing the secretion of GnRH, FSH, and LH.</p> Signup and view all the answers

What is the effect of giving exogenous estrogen to the reproductive system?

<p>Giving exogenous estrogen also has a negative feedback effect on the reproductive system.</p> Signup and view all the answers

What is the role of testosterone in regulating the hypothalamus and pituitary gland in males?

<p>Testosterone has a negative feedback effect on the hypothalamus and pituitary gland, regulating their activity.</p> Signup and view all the answers

What is the main effect of Durateston on the male reproductive system?

<p>Durateston leads to an increase in testosterone levels in the system, which in turn has a negative feedback effect on the hypothalamus and pituitary gland.</p> Signup and view all the answers

What is the mechanism by which giving any of the reproductive sex steroids in males reduces reproductive function?

<p>Negative feedback effect on the hypothalamus and pituitary</p> Signup and view all the answers

What are the additional effects of progestogens on target tissues in males?

<p>Suppression of spermatogenesis</p> Signup and view all the answers

Why do we tend not to use oestrogens in treating peri-anal adenomas in males?

<p>Because they cause bone marrow suppression (anaemia and thrombocytopaenia)</p> Signup and view all the answers

What is the main effect of giving a depot preparation of deslorelin (GnRH agonist) in males?

<p>Reduction of sex behaviors and semen quality</p> Signup and view all the answers

What is the main use of hCG (LH-like) in males?

<p>To confirm the presence of testicular tissue</p> Signup and view all the answers

What is the mechanism by which GnRH exogenous repeated doses reduce endogenous testosterone in males?

<p>Initial receptor stimulation followed by receptor down-regulation</p> Signup and view all the answers

What is the main effect of giving GnRH, FSH, or LH in males to improve semen quality?

<p>Limited impact due to inability to mimic natural release pattern</p> Signup and view all the answers

What is the main effect of progestogens on testosterone levels in males?

<p>Decrease testosterone due to negative feedback effect</p> Signup and view all the answers

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