32 Questions
Which hormone is responsible for the negative feedback effect on the hypothalamus and pituitary gland in the male reproductive system?
Testosterone
What effect does adding progesterone to the male reproductive system have?
Reduces secretion of GnRH
What is the main effect of Durateston on the male reproductive system?
Increases testosterone production
What is the primary function of large negative feedback loops in the control of male reproduction?
Reduce secretion of GnRH
What hormone is responsible for the regulation of the hypothalamus and pituitary gland in the male reproductive system?
Testosterone
What happens to the testicles when there is no activation of the gonad in the male reproductive system?
Decrease in size
What effect does adding exogenous oestrogen to the male reproductive system have?
Reduces secretion of GnRH
What is the role of GnRH in the male reproductive system?
Activates the gonad
What is the main effect of progestogens on testosterone levels in males?
Decrease testosterone due to negative feedback effect
Why do we tend not to use oestrogens in treating peri-anal adenomas in males?
They cause bone marrow suppression
What is the main effect of a depot preparation of deslorelin (GnRH agonist) on male sex behaviors?
Initial stimulation followed by receptor down-regulation
What is the main use of hCG (LH-like) in males?
To confirm the presence of testicular tissue
Which of the following drugs is commonly used to reduce the size of peri-anal adenomas in males?
Progestogens
What is the effect of giving GnRH exogenous repeated doses in males?
Stimulation of release followed by receptor down-regulation
Which of the following drugs can be used to test for the presence of testicular tissue in males?
hCG
What is the main effect of giving FSH or LH in males to improve semen quality?
Limited impact on semen quality
Which of the following drugs has a similar activity to LH in males?
hCG
What is the role of negative feedback loops in the pharmacological control of reproduction in males?
Negative feedback loops effectively regulate the secretion of hormones in the male reproductive system.
How do follicles in the ovary contribute to the regulation of reproduction in females?
Follicles in the ovary produce estrogen, which plays a role in the regulation of reproduction in females.
What hormone is produced by the corpus luteum and how does it affect the reproductive system?
The corpus luteum produces progesterone, which plays a role in regulating the reproductive system.
How does the addition of progesterone to the reproductive system affect the secretion of GnRH, FSH, and LH?
The addition of progesterone has a negative feedback effect, reducing the secretion of GnRH, FSH, and LH.
What is the effect of giving exogenous estrogen to the reproductive system?
Giving exogenous estrogen also has a negative feedback effect on the reproductive system.
What is the role of testosterone in regulating the hypothalamus and pituitary gland in males?
Testosterone has a negative feedback effect on the hypothalamus and pituitary gland, regulating their activity.
What is the main effect of Durateston on the male reproductive system?
Durateston leads to an increase in testosterone levels in the system, which in turn has a negative feedback effect on the hypothalamus and pituitary gland.
What is the mechanism by which giving any of the reproductive sex steroids in males reduces reproductive function?
Negative feedback effect on the hypothalamus and pituitary
What are the additional effects of progestogens on target tissues in males?
Suppression of spermatogenesis
Why do we tend not to use oestrogens in treating peri-anal adenomas in males?
Because they cause bone marrow suppression (anaemia and thrombocytopaenia)
What is the main effect of giving a depot preparation of deslorelin (GnRH agonist) in males?
Reduction of sex behaviors and semen quality
What is the main use of hCG (LH-like) in males?
To confirm the presence of testicular tissue
What is the mechanism by which GnRH exogenous repeated doses reduce endogenous testosterone in males?
Initial receptor stimulation followed by receptor down-regulation
What is the main effect of giving GnRH, FSH, or LH in males to improve semen quality?
Limited impact due to inability to mimic natural release pattern
What is the main effect of progestogens on testosterone levels in males?
Decrease testosterone due to negative feedback effect
Test your knowledge on the pharmacological control of reproduction in males and the role of negative feedback loops. Learn about the production of estrogen and progesterone in the ovary and how these hormones regulate the reproductive process. Discover the effects of adding progesterone to the system and its impact on secretion.
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