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Questions and Answers
What is the main goal in pharmacokinetics?
What is the main goal in pharmacokinetics?
To express the time course of the plasma concentrations mathematically.
Why do compartmental models play a significant role in pharmacokinetics?
Why do compartmental models play a significant role in pharmacokinetics?
They allow the dose and individual processes of ADME to be combined logically to create simple models of a complex system.
What is the salt factor in pharmacokinetics?
What is the salt factor in pharmacokinetics?
The fraction of the salt that is made up of pure drug.
How does the bioavailability factor affect drug administration?
How does the bioavailability factor affect drug administration?
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What is the definition of Effective Dose in pharmacokinetics?
What is the definition of Effective Dose in pharmacokinetics?
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What is the formula to calculate effective dose of a drug?
What is the formula to calculate effective dose of a drug?
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In Example 1, what is the effective dose when a 400-mg tablet of theophylline is administered?
In Example 1, what is the effective dose when a 400-mg tablet of theophylline is administered?
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What is the formula for the rate of drug absorption?
What is the formula for the rate of drug absorption?
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In Example 2, what is the effective dose of a 5-mg tablet of a drug susceptible to acid hydrolysis and metabolism, where only 25% reaches systemic circulation?
In Example 2, what is the effective dose of a 5-mg tablet of a drug susceptible to acid hydrolysis and metabolism, where only 25% reaches systemic circulation?
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For orally administered drugs, in which routes of administration does the process of drug absorption occur?
For orally administered drugs, in which routes of administration does the process of drug absorption occur?
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