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Questions and Answers
What is the main purpose of drug metabolism?
What is the main purpose of drug metabolism?
- To convert lipid-soluble drugs to water-soluble for excretion (correct)
- To increase drug toxicity
- To change free drugs to bound form
- To activate inactive drugs
Which barrier allows only lipid-soluble, less-ionized drugs to pass through?
Which barrier allows only lipid-soluble, less-ionized drugs to pass through?
- Blood-brain barrier (correct)
- Liver barrier
- Meninges barrier
- Placental barrier
Which phase of drug metabolism involves oxidation, reduction, and hydrolysis?
Which phase of drug metabolism involves oxidation, reduction, and hydrolysis?
- Phase IV
- Phase I (correct)
- Phase III
- Phase II
Which organ is NOT mentioned as a site of drug metabolism?
Which organ is NOT mentioned as a site of drug metabolism?
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What is the possible outcome of drugs passing through the placental barrier?
What is the possible outcome of drugs passing through the placental barrier?
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Which type of drugs can pass through inflamed meninges?
Which type of drugs can pass through inflamed meninges?
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How does drug metabolism contribute to drug excretion?
How does drug metabolism contribute to drug excretion?
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What is a common consequence of some drugs displacing others from their binding sites?
What is a common consequence of some drugs displacing others from their binding sites?
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Which type of drugs can pass through the blood-brain barrier?
Which type of drugs can pass through the blood-brain barrier?
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What is one of the functions of Phase II drug metabolism?
What is one of the functions of Phase II drug metabolism?
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