Pharmacokinetics and Sources of Drugs

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What is the main purpose of drug metabolism?

To convert lipid-soluble drugs to water-soluble for excretion (correct)

To increase drug toxicity

To change free drugs to bound form

To activate inactive drugs

Which barrier allows only lipid-soluble, less-ionized drugs to pass through?

Blood-brain barrier (correct)

Liver barrier

Meninges barrier

Placental barrier

Which phase of drug metabolism involves oxidation, reduction, and hydrolysis?

Phase IV

Phase I (correct)

Phase III

Phase II

Which organ is NOT mentioned as a site of drug metabolism?

Heart Signup and view all the answers

What is the possible outcome of drugs passing through the placental barrier?

Teratogenicity Signup and view all the answers

Which type of drugs can pass through inflamed meninges?

Lipid-soluble and less-ionized Signup and view all the answers

How does drug metabolism contribute to drug excretion?

By changing lipid-soluble drugs to water-soluble for excretion Signup and view all the answers

What is a common consequence of some drugs displacing others from their binding sites?

Increased drug action and possible toxicity Signup and view all the answers

Which type of drugs can pass through the blood-brain barrier?

Less-ionized and lipid-soluble drugs Signup and view all the answers

What is one of the functions of Phase II drug metabolism?

Conjugation with glucuronic acid Signup and view all the answers

Pharmacokinetics and Sources of Drugs

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Questions and Answers

What is the main purpose of drug metabolism?

Which barrier allows only lipid-soluble, less-ionized drugs to pass through?

Which phase of drug metabolism involves oxidation, reduction, and hydrolysis?

Which organ is NOT mentioned as a site of drug metabolism?

What is the possible outcome of drugs passing through the placental barrier?

Which type of drugs can pass through inflamed meninges?

How does drug metabolism contribute to drug excretion?

What is a common consequence of some drugs displacing others from their binding sites?

Which type of drugs can pass through the blood-brain barrier?

What is one of the functions of Phase II drug metabolism?

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