Pharmacokinetics and Receptors Quiz
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Questions and Answers

Which type of receptor is affected by benzodiazepines like diazepam?

  • Tyrosine kinase receptors
  • G protein-coupled receptors
  • Ligand-gated ion channels (correct)
  • Enzyme receptors

What property of drugs results in very small range between the concentration for therapeutic effect and toxicity?

  • Non-linear kinetics (correct)
  • Zero-order elimination
  • Linear kinetics
  • First-order elimination

What mechanism does fluoxetine (SSRI) use to exert its antidepressant effect?

  • Enhances the release of GABA
  • Blocks the uptake transporter for serotonin (correct)
  • Blocks the uptake transporter for dopamine
  • Inhibits the reuptake of norepinephrine

What type of elimination is characterized by a constant amount being eliminated per unit time, regardless of the concentration present?

<p>Zero-order elimination (B)</p> Signup and view all the answers

Which phase of drug action involves potentiation of one drug by another?

<p>Metabolism (C)</p> Signup and view all the answers

In drug development, what document is approved as part of the marketing authorization and contains knowledge of pharmacokinetics?

<p>Summary of product characteristics (SPCs) (B)</p> Signup and view all the answers

What is the main focus of pharmacokinetic interactions between drugs?

<p>Alteration of drug absorption and distribution (B)</p> Signup and view all the answers

What type of relationship is linear and predictable in terms of drug action?

<p>Dose-response relationship (C)</p> Signup and view all the answers

Which property characterizes drugs with a 'narrow therapeutic window'?

<p>'Small range between therapeutic effect and toxicity' effect (D)</p> Signup and view all the answers

Which drug exhibits variation in clearance and is the only clinically used drug in its class?

<p>Phenytoin (A)</p> Signup and view all the answers

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