Podcast
Questions and Answers
What determines the concentration of a drug at its site of action?
What determines the concentration of a drug at its site of action?
- Drug metabolism
- Drug excretion routes
- Pharmacodynamics (correct)
- Pharmacokinetics
What type of molecule serves as drug binding targets in addition to proteins?
What type of molecule serves as drug binding targets in addition to proteins?
- Steroids
- DNA (correct)
- Lipids
- Carbohydrates
Which type of drug mimics the effects of endogenous regulators of the receptor it binds to?
Which type of drug mimics the effects of endogenous regulators of the receptor it binds to?
- Noncompetitive inhibitor
- Antagonist
- Competitive inhibitor
- Agonist (correct)
What is the most common route for drug excretion?
What is the most common route for drug excretion?
What is the effect of an antagonist on the function of a receptor?
What is the effect of an antagonist on the function of a receptor?
What two important properties do pharmacologic antagonists have?
What two important properties do pharmacologic antagonists have?
Why is it important for drugs to be reasonably hydrophilic for kidney excretion?
Why is it important for drugs to be reasonably hydrophilic for kidney excretion?
What impact does impaired kidney function have on drug elimination?
What impact does impaired kidney function have on drug elimination?
How can the effects of a competitive pharmacologic antagonist be overcome?
How can the effects of a competitive pharmacologic antagonist be overcome?
Which organ is responsible for most of the enzymatic drug-metabolizing reactions?
Which organ is responsible for most of the enzymatic drug-metabolizing reactions?
What is a common consequence of drugs inhibiting drug-metabolizing enzymes?
What is a common consequence of drugs inhibiting drug-metabolizing enzymes?
According to pharmacology, what relationship exists between a drug's concentration at its site of action and its action?
According to pharmacology, what relationship exists between a drug's concentration at its site of action and its action?
What does pharmacokinetics primarily concern?
What does pharmacokinetics primarily concern?
Which of the following is NOT a process involved in pharmacokinetics?
Which of the following is NOT a process involved in pharmacokinetics?
What is first-pass metabolism in relation to drug administration?
What is first-pass metabolism in relation to drug administration?
Which route of drug administration allows for direct absorption into the systemic venous circulation?
Which route of drug administration allows for direct absorption into the systemic venous circulation?
What can affect the rate and efficiency of drug absorption?
What can affect the rate and efficiency of drug absorption?
Which process involves movement of drug molecules through different body compartments and barriers?
Which process involves movement of drug molecules through different body compartments and barriers?
