Pharmacokinetics Part 1

Pharmacokinetics is the study of drug movement throughout the body.

Routes of drug administration include oral, nasal, rectal, and intrathecal/intraventricular.

The blood-brain barrier prevents the absorption of drugs into the central nervous system.

Topical application is used when a systemic effect of the drug is desired.

Passive diffusion involves the movement of a drug from an area of low concentration to an area of high concentration.

Drugs that are highly lipid-soluble are more likely to pass through the blood-brain barrier.

True or false: The most important consequence of drug metabolism is the conversion of hydrophilic drugs into more lipid soluble forms.

True or false: The First Pass Effect refers to the rapid metabolism of a drug in the liver or gut wall during its initial passage through the portal circulation.

True or false: Prodrugs are designed to decrease drug bioavailability and increase toxicity.

True or false: The half-life of a drug is the time it takes for the drug concentration in the body to reduce by half.

Which route of administration achieves systemic effects by application of drugs to the skin?

Which process involves the movement of a drug into the bloodstream after administration?

What is the driving force for passive diffusion of a drug?

Which type of absorption relies on a carrier protein to move the drug from an area of higher concentration to an area of lower concentration?

Which process involves the transport of drugs of exceptionally large size across the cell membrane by engulfing the drug particles in a vesicle?

Which route of drug administration provides rapid delivery of drug across the large surface area of mucous membranes of the respiratory tract and pulmonary epithelium?

Which route of drug administration is used when local, rapid effects are needed and drugs need to be introduced directly into the cerebrospinal fluid?

Which route of drug administration refers to the absorption of drugs from the time it is introduced to the body until it reaches the circulating fluids and tissues?

Which barrier typically delays or prevents the absorption of drugs into the central nervous system?

Which term refers to the study of drug movement throughout the body?

Which organ is the most important for drug excretion?

What is the purpose of a prodrug?

What is the primary route of drug excretion?

What is the purpose of a loading dose?

What is the process of moving drugs from blood to urine through tubular 'pumps' called?

Match the following terms with their definitions:

Match the routes of drug administration with their descriptions:

Match the routes of administration with their drug delivery methods:

Match the routes of drug administration with their corresponding areas of absorption:

Match the following drug absorption methods with their descriptions:

Match the following terms with their definitions:

Match the following routes of drug administration with their effects:

Match the following terms with their definitions:

Match the following factors with their influence on drug distribution:

Match the following terms to their definitions:

Match the following processes to their descriptions:

Match the following terminologies with their meanings:

Match the following terms to their definitions: