Pharmacokinetics and Drug Excretion
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Questions and Answers

What is the primary site of excretion of drugs and their metabolites via the urine?

  • The kidney (correct)
  • The liver
  • The biliary tract
  • The gut

What is the ratio of the amount of drug in the body to the drug concentration in the plasma or blood?

  • Bioavailability
  • Half-life
  • Volume of distribution (correct)
  • Clearance

What is clearance concerned with?

  • The rate of drug absorption
  • The rate of drug distribution
  • The rate of drug metabolism
  • The rate of drug elimination (correct)

What is the time required for the amount of drug in the body or blood to fall by 50%?

<p>Half-life (B)</p> Signup and view all the answers

What is the fraction (or percentage) of the administered dose of drug that reaches the systemic circulation?

<p>Bioavailability (C)</p> Signup and view all the answers

What describes the actions of a drug on the body and the influence of drug concentrations on the magnitude of the response?

<p>Pharmacodynamics (B)</p> Signup and view all the answers

What is the primary focus of pharmacology?

<p>The study of substances that interact with living systems through chemical processes (A)</p> Signup and view all the answers

What is a drug, according to pharmacology?

<p>A chemical substance of known structure that produces a biological effect (C)</p> Signup and view all the answers

What is genetic engineering, as mentioned in the context of pharmacology?

<p>The process of altering the DNA in an organism's genome (D)</p> Signup and view all the answers

What is the primary difference between a drug and a medicine?

<p>A drug is a chemical substance, while a medicine is a preparation or formulation (C)</p> Signup and view all the answers

What is an example of a drug that is used to produce a beneficial therapeutic effect?

<p>Losartan (D)</p> Signup and view all the answers

What is an example of a drug that is used to produce a toxic effect on parasites?

<p>Mebendazole (D)</p> Signup and view all the answers

What is the process by which a drug is transferred from the bloodstream to body tissues?

<p>Distribution (D)</p> Signup and view all the answers

What is the primary site of drug metabolism?

<p>Liver (B)</p> Signup and view all the answers

What is the major pathway of excretion of drugs?

<p>Renal (B)</p> Signup and view all the answers

What is the study of the actions of the body on the drug?

<p>Pharmacokinetics (C)</p> Signup and view all the answers

What is the process by which a drug is converted into compounds that are easier to eliminate?

<p>Metabolism (D)</p> Signup and view all the answers

What is the relationship between the individual's genetic makeup and their response to specific drugs?

<p>Pharmacogenomics (A)</p> Signup and view all the answers

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