18 Questions
What is the primary site of excretion of drugs and their metabolites via the urine?
The kidney
What is the ratio of the amount of drug in the body to the drug concentration in the plasma or blood?
Volume of distribution
What is clearance concerned with?
The rate of drug elimination
What is the time required for the amount of drug in the body or blood to fall by 50%?
Half-life
What is the fraction (or percentage) of the administered dose of drug that reaches the systemic circulation?
Bioavailability
What describes the actions of a drug on the body and the influence of drug concentrations on the magnitude of the response?
Pharmacodynamics
What is the primary focus of pharmacology?
The study of substances that interact with living systems through chemical processes
What is a drug, according to pharmacology?
A chemical substance of known structure that produces a biological effect
What is genetic engineering, as mentioned in the context of pharmacology?
The process of altering the DNA in an organism's genome
What is the primary difference between a drug and a medicine?
A drug is a chemical substance, while a medicine is a preparation or formulation
What is an example of a drug that is used to produce a beneficial therapeutic effect?
Losartan
What is an example of a drug that is used to produce a toxic effect on parasites?
Mebendazole
What is the process by which a drug is transferred from the bloodstream to body tissues?
Distribution
What is the primary site of drug metabolism?
Liver
What is the major pathway of excretion of drugs?
Renal
What is the study of the actions of the body on the drug?
Pharmacokinetics
What is the process by which a drug is converted into compounds that are easier to eliminate?
Metabolism
What is the relationship between the individual's genetic makeup and their response to specific drugs?
Pharmacogenomics
This quiz covers the processes of drug excretion, including glomerular filtration, tubular secretion, and tubular reabsorption, as well as pharmacokinetic parameters such as volume of distribution.
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