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Pharmacokinetics and Drug Excretion

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Questions and Answers

What is the primary site of excretion of drugs and their metabolites via the urine?

The kidney (correct)

The liver

The biliary tract

The gut

What is the ratio of the amount of drug in the body to the drug concentration in the plasma or blood?

Bioavailability

Half-life

Volume of distribution (correct)

Clearance

What is clearance concerned with?

The rate of drug absorption

The rate of drug distribution

The rate of drug metabolism

The rate of drug elimination (correct)

What is the time required for the amount of drug in the body or blood to fall by 50%?

Half-life Signup and view all the answers

What is the fraction (or percentage) of the administered dose of drug that reaches the systemic circulation?

Bioavailability Signup and view all the answers

What describes the actions of a drug on the body and the influence of drug concentrations on the magnitude of the response?

Pharmacodynamics Signup and view all the answers

What is the primary focus of pharmacology?

The study of substances that interact with living systems through chemical processes Signup and view all the answers

What is a drug, according to pharmacology?

A chemical substance of known structure that produces a biological effect Signup and view all the answers

What is genetic engineering, as mentioned in the context of pharmacology?

The process of altering the DNA in an organism's genome Signup and view all the answers

What is the primary difference between a drug and a medicine?

A drug is a chemical substance, while a medicine is a preparation or formulation Signup and view all the answers

What is an example of a drug that is used to produce a beneficial therapeutic effect?

Losartan Signup and view all the answers

What is an example of a drug that is used to produce a toxic effect on parasites?

Mebendazole Signup and view all the answers

What is the process by which a drug is transferred from the bloodstream to body tissues?

Distribution Signup and view all the answers

What is the primary site of drug metabolism?

Liver Signup and view all the answers

What is the major pathway of excretion of drugs?

Renal Signup and view all the answers

What is the study of the actions of the body on the drug?

Pharmacokinetics Signup and view all the answers

What is the process by which a drug is converted into compounds that are easier to eliminate?

Metabolism Signup and view all the answers

What is the relationship between the individual's genetic makeup and their response to specific drugs?

Pharmacogenomics Signup and view all the answers