Pharmacokinetics and Drug Absorption Quiz
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Questions and Answers

Which factor affects drug absorption through sublingual and buccal routes?

  • Particle size
  • Lipophilicity of the drug
  • Ventilation rate
  • Molecular weight of the drug (correct)
  • How does increased small intestine transit time (SITT) affect drug absorption?

  • It decreases the time needed for drug absorption
  • It increases the time needed for drug absorption (correct)
  • It has no effect on drug absorption
  • It decreases drug-drug interactions
  • Which condition would likely result in decreased drug absorption due to reduced stomach acid?

  • Achlorhydria (correct)
  • Malabsorption
  • Ulcerative colitis
  • Crohn’s disease
  • In which type of diffusion does a lipophilic drug move through capillary walls?

    <p>Subcutaneous diffusion</p> Signup and view all the answers

    How do proton pump inhibitors like omeprazole affect drug absorption when taken with ketoconazole?

    <p>Decrease ketoconazole absorption</p> Signup and view all the answers

    Which region is the major site for drug absorption?

    <p>Ileum</p> Signup and view all the answers

    What accelerates gastric emptying and promotes the absorption of drugs like aspirin in the duodenum?

    <p>Metoclopramide</p> Signup and view all the answers

    Which physicochemical property of a drug affects its absorption and excretion in the body?

    <p>Log P</p> Signup and view all the answers

    Which type of drugs are absorbed quickly in the gut but excreted poorly in the kidney?

    <p>Lipid soluble drugs</p> Signup and view all the answers

    What is the primary purpose of enteric coating on oral drugs?

    <p>To protect the active ingredient in the stomach</p> Signup and view all the answers

    How does high caloric food affect drug absorption?

    <p>Delays transit time through the gut</p> Signup and view all the answers

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