Pharmacokinetics and Biopharmaceutics Basics
15 Questions
11 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What does biopharmaceutics primarily study?

  • The chemical synthesis of pharmaceuticals.
  • The historical development of pharmacology.
  • The relationship between the biological effects of a drug and its physicochemical properties. (correct)
  • The market trends of pharmaceutical sales.

Which phase involves the mathematical analysis of drug absorption and distribution processes?

  • Pharmacodynamic Phase
  • Therapeutic Phase
  • Pharmaceutical Phase
  • Pharmacokinetic Phase (correct)

Which of the following factors does NOT influence drug absorption?

  • Dissolution rate
  • Drug stability
  • Patient age (correct)
  • Chemical nature of the drug

What are some formulation properties that affect drug absorption?

<p>Chemical structure and dosage form (B)</p> Signup and view all the answers

Which of the following best describes the pharmacodynamic phase?

<p>The effects of the drug on the body and the mechanisms of action. (B)</p> Signup and view all the answers

What does pharmacodynamics primarily establish a relationship between?

<p>Drug concentration and pharmacological response (C)</p> Signup and view all the answers

Which of the following represents a non-invasive method for obtaining biological specimens?

<p>Saliva sample (D)</p> Signup and view all the answers

What is the purpose of plasma concentration assays?

<p>To assess the pharmacologic outcomes of drug dosing (C)</p> Signup and view all the answers

Which assay technique is commonly used to separate a drug from other substances?

<p>Chromatography (C)</p> Signup and view all the answers

What does serum represent in the context of biological specimens?

<p>Supernatant from coagulated blood (B)</p> Signup and view all the answers

Which of the following is a patient-specific consideration in pharmacokinetics?

<p>Drug metabolism rates (C)</p> Signup and view all the answers

What is the purpose of therapeutic drug monitoring (TDM)?

<p>To manage drugs with narrow therapeutic index (B)</p> Signup and view all the answers

Which aspect of pharmacokinetics involves the development of models that predict drug disposition?

<p>Theoretical aspects (C)</p> Signup and view all the answers

In which category of pharmacokinetics are biologic sampling techniques developed?

<p>Experimental aspects (C)</p> Signup and view all the answers

What is the main goal of population pharmacokinetics?

<p>Understanding variations due to individual characteristics (C)</p> Signup and view all the answers

Flashcards

Biopharmaceutics

The study of how a drug's physical and chemical properties affect its biological effects in the body.

Pharmacokinetics

The study of how the body handles a drug over time, from absorption to distribution, to elimination.

Pharmaceutical Phase

The initial stage where the drug is prepared into its dosage form.

Pharmacokinetic Phase

The stage where the drug is absorbed, distributed, and eliminated by the body.

Signup and view all the flashcards

Pharmacodynamic Phase

The stage where the drug interacts with its target in the body and produces its effects.

Signup and view all the flashcards

Classical Pharmacokinetics

The study of how a drug's concentration changes over time in the body, helping to determine the optimal dosage.

Signup and view all the flashcards

Population Pharmacokinetics

Incorporating patient-specific factors like age, gender, and genetics to personalize drug dosages and optimize treatment.

Signup and view all the flashcards

Therapeutic Drug Monitoring (TDM)

Monitoring drug levels in the body to ensure effective and safe treatment, especially for drugs with a narrow therapeutic window.

Signup and view all the flashcards

Toxicokinetics

The study of how toxins or poisons behave in the body, similar to pharmacokinetics but focusing on harmful substances.

Signup and view all the flashcards

Pharmacodynamics

The study of how a drug's concentration at the site of action relates to its effects on the body.

Signup and view all the flashcards

Blood Concentrations

Blood samples are a crucial source for drug analysis. It helps in monitoring drug levels in the body.

Signup and view all the flashcards

Plasma Concentration-Time Curve

This curve shows the relationship between drug concentration in plasma and time after administration. It provides information about drug absorption, distribution, and elimination.

Signup and view all the flashcards

Drug Concentration Assays

These assays identify and quantify drugs in various biological samples. They play a key role in determining drug efficacy, monitoring drug levels, and investigating forensic cases.

Signup and view all the flashcards

Chromatography

A method used in drug analysis, separating drugs from other substances using different chemical and physical properties. This helps identify and quantify specific drugs.

Signup and view all the flashcards

More Like This

Use Quizgecko on...
Browser
Open
Browser
Browser