Extravascular Absorption in Pharmacokinetics
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Questions and Answers

What is the absorption rate constant?

  • The rate at which the drug appears in the systemic circulation after drug administration
  • The rate at which the drug is distributed to different parts of the body
  • The rate at which the drug is eliminated from the body
  • The rate constant that accounts for disintegration, dissolution, and absorption in drug absorption (correct)

What needs to happen before a drug in a solid dosage form can be absorbed into the systemic circulation?

  • The drug needs to be eliminated from the body
  • The drug needs to undergo metabolism in the liver
  • The drug needs to be in solution after disintegration and dissolution (correct)
  • The drug needs to be distributed to different parts of the body

What does a larger absorption rate constant result in?

  • Faster rate of drug absorption (correct)
  • Slower rate of drug absorption
  • No effect on the rate of drug absorption
  • Faster rate of drug elimination

What is the operative rate constant that accounts for all necessary steps required for drug absorption?

<p>Absorption rate constant (A)</p> Signup and view all the answers

Which factor can cause the absorption rate constant (ka) of different dosage forms of the same drug to be different?

<p>Differences in formulation characteristics (B)</p> Signup and view all the answers

Absorption rate constant (ka) describes the overall absorption process

<p>True (A)</p> Signup and view all the answers

Tablets and capsules have to dissolve before the drug can be absorbed into the systemic circulation

<p>True (A)</p> Signup and view all the answers

The absorption rate constant (ka) has units of time-1

<p>True (A)</p> Signup and view all the answers

A larger absorption rate constant results in a slower rate of drug absorption

<p>False (B)</p> Signup and view all the answers

The rate constant that accounts for all necessary steps required for drug absorption is (Ka)

<p>True (A)</p> Signup and view all the answers

What is the absorption rate constant (ka) responsible for?

<p>Accounting for all necessary steps required for drug absorption (B)</p> Signup and view all the answers

How does a larger absorption rate constant affect the rate of drug absorption?

<p>Speeds up the rate of drug absorption (B)</p> Signup and view all the answers

What needs to happen before a drug in a solid dosage form can be absorbed into the systemic circulation?

<p>The drug must disintegrate (C)</p> Signup and view all the answers

What describes the overall absorption process?

<p>Absorption rate constant (ka) (D)</p> Signup and view all the answers

What factor can cause the absorption rate constant (ka) of different dosage forms of the same drug to be different?

<p>Differences in formulation characteristics (B)</p> Signup and view all the answers

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