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Questions and Answers
What is the absorption rate constant?
What is the absorption rate constant?
- The rate at which the drug appears in the systemic circulation after drug administration
- The rate at which the drug is distributed to different parts of the body
- The rate at which the drug is eliminated from the body
- The rate constant that accounts for disintegration, dissolution, and absorption in drug absorption (correct)
What needs to happen before a drug in a solid dosage form can be absorbed into the systemic circulation?
What needs to happen before a drug in a solid dosage form can be absorbed into the systemic circulation?
- The drug needs to be eliminated from the body
- The drug needs to undergo metabolism in the liver
- The drug needs to be in solution after disintegration and dissolution (correct)
- The drug needs to be distributed to different parts of the body
What does a larger absorption rate constant result in?
What does a larger absorption rate constant result in?
- Faster rate of drug absorption (correct)
- Slower rate of drug absorption
- No effect on the rate of drug absorption
- Faster rate of drug elimination
What is the operative rate constant that accounts for all necessary steps required for drug absorption?
What is the operative rate constant that accounts for all necessary steps required for drug absorption?
Which factor can cause the absorption rate constant (ka) of different dosage forms of the same drug to be different?
Which factor can cause the absorption rate constant (ka) of different dosage forms of the same drug to be different?
Absorption rate constant (ka) describes the overall absorption process
Absorption rate constant (ka) describes the overall absorption process
Tablets and capsules have to dissolve before the drug can be absorbed into the systemic circulation
Tablets and capsules have to dissolve before the drug can be absorbed into the systemic circulation
The absorption rate constant (ka) has units of time-1
The absorption rate constant (ka) has units of time-1
A larger absorption rate constant results in a slower rate of drug absorption
A larger absorption rate constant results in a slower rate of drug absorption
The rate constant that accounts for all necessary steps required for drug absorption is (Ka)
The rate constant that accounts for all necessary steps required for drug absorption is (Ka)
What is the absorption rate constant (ka) responsible for?
What is the absorption rate constant (ka) responsible for?
How does a larger absorption rate constant affect the rate of drug absorption?
How does a larger absorption rate constant affect the rate of drug absorption?
What needs to happen before a drug in a solid dosage form can be absorbed into the systemic circulation?
What needs to happen before a drug in a solid dosage form can be absorbed into the systemic circulation?
What describes the overall absorption process?
What describes the overall absorption process?
What factor can cause the absorption rate constant (ka) of different dosage forms of the same drug to be different?
What factor can cause the absorption rate constant (ka) of different dosage forms of the same drug to be different?