Extravascular Absorption in Pharmacokinetics
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Questions and Answers

What is the absorption rate constant?

  • The rate at which the drug appears in the systemic circulation after drug administration
  • The rate at which the drug is distributed to different parts of the body
  • The rate at which the drug is eliminated from the body
  • The rate constant that accounts for disintegration, dissolution, and absorption in drug absorption (correct)

    • What needs to happen before a drug in a solid dosage form can be absorbed into the systemic circulation?

  • The drug needs to be eliminated from the body
  • The drug needs to undergo metabolism in the liver
  • The drug needs to be in solution after disintegration and dissolution (correct)
  • The drug needs to be distributed to different parts of the body

    • What does a larger absorption rate constant result in?

  • Faster rate of drug absorption (correct)
  • Slower rate of drug absorption
  • No effect on the rate of drug absorption
  • Faster rate of drug elimination

    • What is the operative rate constant that accounts for all necessary steps required for drug absorption?

    <p>Absorption rate constant</p> Signup and view all the answers

    Which factor can cause the absorption rate constant (ka) of different dosage forms of the same drug to be different?

    <p>Differences in formulation characteristics</p> Signup and view all the answers

    Absorption rate constant (ka) describes the overall absorption process

    <p>True</p> Signup and view all the answers

    Tablets and capsules have to dissolve before the drug can be absorbed into the systemic circulation

    <p>True</p> Signup and view all the answers

    The absorption rate constant (ka) has units of time-1

    <p>True</p> Signup and view all the answers

    A larger absorption rate constant results in a slower rate of drug absorption

    <p>False</p> Signup and view all the answers

    The rate constant that accounts for all necessary steps required for drug absorption is (Ka)

    <p>True</p> Signup and view all the answers

    What is the absorption rate constant (ka) responsible for?

    <p>Accounting for all necessary steps required for drug absorption</p> Signup and view all the answers

    How does a larger absorption rate constant affect the rate of drug absorption?

    <p>Speeds up the rate of drug absorption</p> Signup and view all the answers

    What needs to happen before a drug in a solid dosage form can be absorbed into the systemic circulation?

    <p>The drug must disintegrate</p> Signup and view all the answers

    What describes the overall absorption process?

    <p>Absorption rate constant (ka)</p> Signup and view all the answers

    What factor can cause the absorption rate constant (ka) of different dosage forms of the same drug to be different?

    <p>Differences in formulation characteristics</p> Signup and view all the answers

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