Pharmacokinetics 1: Drug Absorption, Distribution, Metabolism, and Elimination
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Questions and Answers

Which process involves the movement of a drug from the site of administration to the blood?

  • Absorption (correct)
  • Elimination
  • Metabolism
  • Distribution

What is the term for 'cell drinking', a form of endocytosis where the cell membrane surrounds a molecule to form a vesicle which is then degraded by lysosomal enzymes?

  • Diffusion
  • Pinocytosis (correct)
  • Carrier-mediated transport
  • Simple diffusion

What is the main factor influencing the rate of absorption of oral ingestion of drugs?

  • Lipid solubility (correct)
  • Blood flow to tissue
  • Body mass
  • Physiochemical properties

Which route of administration is suitable for non-irritating drugs and allows for self-administration?

<p>Subcutaneous (A)</p> Signup and view all the answers

What term describes the concentration of a drug at the site of action or in the tissues?

<p>Distribution (C)</p> Signup and view all the answers

Which process involves crossing cellular barriers through carrier-mediated transport and pinocytosis?

<p>Absorption (A)</p> Signup and view all the answers

What type of drugs are better absorbed due to their ability to reach systemic circulation quickly and avoid first-pass elimination?

<p>Lipid-soluble drugs (B)</p> Signup and view all the answers

Which route of administration is best for drugs causing local tissue irritation?

<p>Intravenous (B)</p> Signup and view all the answers

Which factor affects drug absorption by influencing the concentration at the site of action or in the tissues?

<p>Blood flow to tissue (A)</p> Signup and view all the answers

What term describes the concentration of a drug at the site of action or in the tissues?

<p>Dose and concentration (D)</p> Signup and view all the answers

Which type of drugs are better absorbed due to their ability to reach systemic circulation quickly and avoid first-pass elimination?

<p>Sublingual drugs (D)</p> Signup and view all the answers

What process involves the movement of a drug from the site of administration to the blood?

<p>Absorption (B)</p> Signup and view all the answers

Which route of administration is best for drugs causing local tissue irritation?

<p>Intravenous (C)</p> Signup and view all the answers

What factor affects drug absorption by influencing the area of absorption?

<p>Site of administration (C)</p> Signup and view all the answers

Which process involves crossing cellular barriers through carrier-mediated transport and pinocytosis?

<p>Absorption (B)</p> Signup and view all the answers

Which route of administration is suitable for non-irritating drugs and allows for self-administration?

<p>Transdermal (C)</p> Signup and view all the answers

What is the term for the process of movement of a drug from the site of administration to the blood?

<p>Absorption (B)</p> Signup and view all the answers

Which type of drugs are better absorbed due to their ability to reach systemic circulation quickly and avoid first-pass elimination?

<p>Lipid-soluble drugs (D)</p> Signup and view all the answers

What term describes the concentration of a drug at the site of action or in the tissues?

<p>Distribution (D)</p> Signup and view all the answers

Which factor affects drug absorption by influencing the area of absorption?

<p>Site of administration (A)</p> Signup and view all the answers

What is the term for 'cell drinking', a form of endocytosis where the cell membrane surrounds a molecule to form a vesicle which is then degraded by lysosomal enzymes?

<p>Pinocytosis (C)</p> Signup and view all the answers

Which process involves crossing cellular barriers through carrier-mediated transport and pinocytosis?

<p>Absorption (D)</p> Signup and view all the answers

What is the main factor influencing the rate of absorption of oral ingestion of drugs?

<p>$H^+$ and $A^-$ ion concentrations (D)</p> Signup and view all the answers

Which route of administration is best for drugs causing local tissue irritation?

<p>$Intraarterial$ (C)</p> Signup and view all the answers

What process involves crossing cellular barriers through diffusion and is influenced by lipid solubility?

<p>$Absorption$ (B)</p> Signup and view all the answers

Which route of administration is suitable for non-irritating drugs and allows for self-administration?

<p>Transdermal (C)</p> Signup and view all the answers

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