Pharmacokinetics 1: Drug Absorption, Distribution, Metabolism, and Elimination
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Questions and Answers

Which process involves the movement of a drug from the site of administration to the blood?

  • Absorption (correct)
  • Elimination
  • Metabolism
  • Distribution
  • What is the term for 'cell drinking', a form of endocytosis where the cell membrane surrounds a molecule to form a vesicle which is then degraded by lysosomal enzymes?

  • Diffusion
  • Pinocytosis (correct)
  • Carrier-mediated transport
  • Simple diffusion
  • What is the main factor influencing the rate of absorption of oral ingestion of drugs?

  • Lipid solubility (correct)
  • Blood flow to tissue
  • Body mass
  • Physiochemical properties
  • Which route of administration is suitable for non-irritating drugs and allows for self-administration?

    <p>Subcutaneous</p> Signup and view all the answers

    What term describes the concentration of a drug at the site of action or in the tissues?

    <p>Distribution</p> Signup and view all the answers

    Which process involves crossing cellular barriers through carrier-mediated transport and pinocytosis?

    <p>Absorption</p> Signup and view all the answers

    What type of drugs are better absorbed due to their ability to reach systemic circulation quickly and avoid first-pass elimination?

    <p>Lipid-soluble drugs</p> Signup and view all the answers

    Which route of administration is best for drugs causing local tissue irritation?

    <p>Intravenous</p> Signup and view all the answers

    Which factor affects drug absorption by influencing the concentration at the site of action or in the tissues?

    <p>Blood flow to tissue</p> Signup and view all the answers

    What term describes the concentration of a drug at the site of action or in the tissues?

    <p>Dose and concentration</p> Signup and view all the answers

    Which type of drugs are better absorbed due to their ability to reach systemic circulation quickly and avoid first-pass elimination?

    <p>Sublingual drugs</p> Signup and view all the answers

    What process involves the movement of a drug from the site of administration to the blood?

    <p>Absorption</p> Signup and view all the answers

    Which route of administration is best for drugs causing local tissue irritation?

    <p>Intravenous</p> Signup and view all the answers

    What factor affects drug absorption by influencing the area of absorption?

    <p>Site of administration</p> Signup and view all the answers

    Which process involves crossing cellular barriers through carrier-mediated transport and pinocytosis?

    <p>Absorption</p> Signup and view all the answers

    Which route of administration is suitable for non-irritating drugs and allows for self-administration?

    <p>Transdermal</p> Signup and view all the answers

    What is the term for the process of movement of a drug from the site of administration to the blood?

    <p>Absorption</p> Signup and view all the answers

    Which type of drugs are better absorbed due to their ability to reach systemic circulation quickly and avoid first-pass elimination?

    <p>Lipid-soluble drugs</p> Signup and view all the answers

    What term describes the concentration of a drug at the site of action or in the tissues?

    <p>Distribution</p> Signup and view all the answers

    Which factor affects drug absorption by influencing the area of absorption?

    <p>Site of administration</p> Signup and view all the answers

    What is the term for 'cell drinking', a form of endocytosis where the cell membrane surrounds a molecule to form a vesicle which is then degraded by lysosomal enzymes?

    <p>Pinocytosis</p> Signup and view all the answers

    Which process involves crossing cellular barriers through carrier-mediated transport and pinocytosis?

    <p>Absorption</p> Signup and view all the answers

    What is the main factor influencing the rate of absorption of oral ingestion of drugs?

    <p>$H^+$ and $A^-$ ion concentrations</p> Signup and view all the answers

    Which route of administration is best for drugs causing local tissue irritation?

    <p>$Intraarterial$</p> Signup and view all the answers

    What process involves crossing cellular barriers through diffusion and is influenced by lipid solubility?

    <p>$Absorption$</p> Signup and view all the answers

    Which route of administration is suitable for non-irritating drugs and allows for self-administration?

    <p>Transdermal</p> Signup and view all the answers

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