Podcast
Questions and Answers
What does pharmacokinetics study?
What does pharmacokinetics study?
- The rate and extent of drug transport in the body (correct)
- The chemical structure of drugs
- The effect of drugs on the body
- The psychological impact of drugs
Which factor determines the rate of drug action in the body?
Which factor determines the rate of drug action in the body?
- Rate of drug absorption (correct)
- Rate of drug distribution
- Rate of drug metabolism
- Rate of drug excretion
What is the role of plasma protein binding in pharmacokinetics?
What is the role of plasma protein binding in pharmacokinetics?
- To decrease drug distribution
- To regulate the rate of drug elimination
- To influence the free drug concentration and distribution (correct)
- To increase drug absorption
In pharmacokinetics, what does 'ADME' stand for?
In pharmacokinetics, what does 'ADME' stand for?
What determines the rate of drug transport to the target tissue of pharmacological action?
What determines the rate of drug transport to the target tissue of pharmacological action?
What does the rate of absorption from intramuscular (IM) and subcutaneous (SC) routes depend on?
What does the rate of absorption from intramuscular (IM) and subcutaneous (SC) routes depend on?
Which route is most preferred for drug administration?
Which route is most preferred for drug administration?
What is the purpose of ensuring that the effective elimination half-life of a drug ideally equals the dosing interval?
What is the purpose of ensuring that the effective elimination half-life of a drug ideally equals the dosing interval?
What are common routes of drug administration other than per oral (PO), intramuscular (IM), subcutaneous (SC), and intravenous (IV) injections and IV infusion?
What are common routes of drug administration other than per oral (PO), intramuscular (IM), subcutaneous (SC), and intravenous (IV) injections and IV infusion?
Why is the oral route not suitable for drugs that are not stable in the gut?
Why is the oral route not suitable for drugs that are not stable in the gut?
What does pharmacokinetics study?
What does pharmacokinetics study?
What determines the rate of drug action in the body?
What determines the rate of drug action in the body?
What is the purpose of ensuring that the effective elimination half-life of a drug ideally equals the dosing interval?
What is the purpose of ensuring that the effective elimination half-life of a drug ideally equals the dosing interval?
What does 'ADME' stand for in pharmacokinetics?
What does 'ADME' stand for in pharmacokinetics?
Why is the oral route not suitable for drugs that are not stable in the gut?
Why is the oral route not suitable for drugs that are not stable in the gut?
What factors determine the extent of drug that reaches the site of drug action?
What factors determine the extent of drug that reaches the site of drug action?
Why should the effective elimination half-life of a drug ideally be equal to the dosing interval?
Why should the effective elimination half-life of a drug ideally be equal to the dosing interval?
What is the significance of the equilibrium steady state in drug administration?
What is the significance of the equilibrium steady state in drug administration?
How does the dosing frequency of a drug in humans relate to the drug's half-life and unbound steady-state concentration?
How does the dosing frequency of a drug in humans relate to the drug's half-life and unbound steady-state concentration?
What factors determine the rate of absorption from intramuscular (IM) and subcutaneous (SC) routes?
What factors determine the rate of absorption from intramuscular (IM) and subcutaneous (SC) routes?
