Pharmacokinetic Principles of Drugs of Abuse Quiz
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Questions and Answers

Which factor influences the increased abuse potential of nicotine, cocaine, cannabis, and fentanyl?

  • Potential metabolites formed
  • Primary route of elimination
  • Key pharmacokinetic parameters (correct)
  • Extent of ionization

    • What is a pharmacokinetic consideration for psychotropic drugs related to enhanced self-administration?

  • Low protein binding
  • Rapid distribution to the brain (correct)
  • Rapid absorption
  • High free drug clearance

    • What is the primary route of elimination for the drugs of abuse presented in class?

  • Renal excretion (correct)
  • Biliary excretion
  • Metabolism by CYP enzymes
  • Exhalation through lungs

    • What influences physical dependence and withdrawal related to psychotropic drugs?

    <p>Constant exposure</p> Signup and view all the answers

    What pharmacokinetic consequence influences the preference of some routes of administration over others?

    <p>Rapid absorption</p> Signup and view all the answers

    Which factor contributes to the increased abuse potential of nicotine, cocaine, cannabis, and fentanyl?

    <p>Rapid absorption and distribution to the brain</p> Signup and view all the answers

    What is a key pharmacokinetic consideration related to enhanced self-administration of psychotropic drugs?

    <p>Rapid entry into and exit from the brain</p> Signup and view all the answers

    What influences the preference of some routes of administration over others based on pharmacokinetic consequences?

    <p>Rapid absorption and distribution to the brain</p> Signup and view all the answers

    What influences physical dependence and withdrawal related to psychotropic drugs?

    <p>Constant exposure and rapid elimination from the system</p> Signup and view all the answers

    What is a pharmacokinetic consequence that influences the increased abuse potential of nicotine, cocaine, cannabis, and fentanyl?

    <p>Rapid distribution to the brain and low protein binding</p> Signup and view all the answers

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