Podcast
Questions and Answers
Which phase of the pharmacokinetic process involves the movement of drug from the site of administration to the blood circulation?
Which phase of the pharmacokinetic process involves the movement of drug from the site of administration to the blood circulation?
- Metabolism
- Distribution
- Absorption (correct)
- Excretion
What term is commonly used to describe the rate and extent of drug input in the context of absorption?
What term is commonly used to describe the rate and extent of drug input in the context of absorption?
- Half-life
- Distribution coefficient
- Clearance
- Bioavailability (correct)
Which route of drug administration exhibits essentially 100% bioavailability?
Which route of drug administration exhibits essentially 100% bioavailability?
- Intramuscular
- Intravenous (correct)
- Oral
- Subcutaneous
What is the process by which a drug diffuses or transfers from intravascular to extravascular spaces (body tissues)?
What is the process by which a drug diffuses or transfers from intravascular to extravascular spaces (body tissues)?
What is metabolism in the context of pharmacokinetics?
What is metabolism in the context of pharmacokinetics?
Which phase of pharmacokinetics involves the elimination of unchanged drug or its metabolite from the body via renal, biliary, or pulmonary routes?
Which phase of pharmacokinetics involves the elimination of unchanged drug or its metabolite from the body via renal, biliary, or pulmonary routes?
In the context of absorption, what does the term 'bioavailability' refer to?
In the context of absorption, what does the term 'bioavailability' refer to?
What is the primary focus of pharmacokinetics?
What is the primary focus of pharmacokinetics?
Which factor does NOT affect drug absorption through the oral route?
Which factor does NOT affect drug absorption through the oral route?
Why might change in formulation lead to altered clinical response for certain drugs?
Why might change in formulation lead to altered clinical response for certain drugs?
In which situation may oral paracetamol show a slow effect?
In which situation may oral paracetamol show a slow effect?
What happens when certain drugs form complexes with food components?
What happens when certain drugs form complexes with food components?
Why may insulin show a poor response after repeated injections in the same site?
Why may insulin show a poor response after repeated injections in the same site?
What is the process of drug distribution primarily concerned with?
What is the process of drug distribution primarily concerned with?
Which factor does NOT affect drug distribution within the body?
Which factor does NOT affect drug distribution within the body?
Why is blood flow to the liver important for certain drugs?
Why is blood flow to the liver important for certain drugs?
What prevents many drug molecules from entering the surrounding tissue in brain capillaries?
What prevents many drug molecules from entering the surrounding tissue in brain capillaries?
Which protein is primarily responsible for binding many acidic drugs and a few basic drugs in circulating plasma?
Which protein is primarily responsible for binding many acidic drugs and a few basic drugs in circulating plasma?
Which factor can increase the fraction of unbound drug in the body?
Which factor can increase the fraction of unbound drug in the body?
