Pharmacognosy - Leaves Overview

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Questions and Answers

The whole ______ are those usually sold to the public.

leaves

The other grades are used for making ______.

galenicals

The drug is packed somewhat loosely, in ______.

bales

The drug is sent by rail to ______.

<p>Port Sudan</p> Signup and view all the answers

From Port Sudan, the drug is ______.

<p>exported</p> Signup and view all the answers

The mesophyll consists of upper and lower ______ layers.

<p>palisade</p> Signup and view all the answers

The mesophyll contains cluster crystals about 15-20 m in ______.

<p>diameter</p> Signup and view all the answers

The midrib is ______.

<p>biconvex</p> Signup and view all the answers

Below the midrib ______ is a zone of collenchyma.

<p>bundle</p> Signup and view all the answers

The median spongy ______ is part of the mesophyll.

<p>mesophyll</p> Signup and view all the answers

They seldom exceed ______ in length.

<p>40 mm</p> Signup and view all the answers

The color can be described as ______-green.

<p>yellowish</p> Signup and view all the answers

An alternative color description is ______-green.

<p>grayish</p> Signup and view all the answers

They are more asymmetric at the ______.

<p>base</p> Signup and view all the answers

The edges are rather more broken and curled due to ______.

<p>compression</p> Signup and view all the answers

Digitalis leaves are usually ovate-lanceolate to broadly ______ in shape.

<p>ovate</p> Signup and view all the answers

Often shows impressions due to the ______ markings.

<p>press</p> Signup and view all the answers

Digitalis leaves are produced commercially in ______ and Eastern Europe.

<p>Holland</p> Signup and view all the answers

Digitalis leaves are about 10-30 cm long and ______ cm wide.

<p>4-10</p> Signup and view all the answers

Chemical tests involve ether extract of hydrolysed acid solution of drug gives with methanolic magnesium acetate solution to create a ______ color in daylight.

<p>pink</p> Signup and view all the answers

The leaves of Digitalis are ______ and about 10-30 cm long.

<p>petiolate</p> Signup and view all the answers

A chemical test gives an ______ color in daylight.

<p>orange</p> Signup and view all the answers

Digitalis leaves may vary in shape, but they are usually ______-lanceolate.

<p>ovate</p> Signup and view all the answers

A ______ in filtered ultraviolet light can also be observed during the test.

<p>yellowish-green</p> Signup and view all the answers

A ______ color is observed in filtered ultraviolet light.

<p>pale greenish-orange</p> Signup and view all the answers

It increases the ______ and improves the tone of the cardiac muscle.

<p>contractility</p> Signup and view all the answers

Both reactions resulting in a slower negative ______ but much stronger.

<p>chronotrope</p> Signup and view all the answers

It results in a ______ but much stronger heart beat.

<p>stronger</p> Signup and view all the answers

It leads to a much stronger (positive ______) heart beat.

<p>inotrope</p> Signup and view all the answers

The reactions improve the tone of the ______ muscle.

<p>cardiac</p> Signup and view all the answers

Flashcards

Whole senna leaves

The type of senna leaves typically sold to consumers.

Other grades of senna

Grades of senna leaves used in the production of medications.

Packing of senna

The method of preparing senna leaves for transport after processing.

Port Sudan

The primary port used for exporting senna leaves.

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Senna transportation

The mode of transportation used to move senna from processing facilities to the port.

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Mesophyll

The layer within a leaf containing cells specialized for photosynthesis.

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Palisade Mesophyll

The mesophyll layer of a leaf located closer to the upper surface, often containing more chloroplasts for efficient light absorption.

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Spongy Mesophyll

The mesophyll layer of a leaf located closer to the lower surface, containing loosely packed cells with air spaces for gas exchange.

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Cluster Crystals

Crystals found in the mesophyll layer of some plants, often in clusters.

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Midrib

A thickened vascular tissue in the center of a leaf, providing support and transport.

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Object Length

The length of the described object is usually less than 40 mm.

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Object Color

The color of the object is typically yellowish-green.

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Alternate Object Color

The color of the object can also be grayish-green.

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Base Shape

The shape of the object at its base is generally less asymmetric.

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Alternate Base Shape

The shape of the object at its base is often more asymmetric.

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Positive Chronotrope

When a substance speeds up the heart rate.

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Negative Chronotrope

When a substance slows down the heart rate.

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Positive Inotrope

When a substance increases the strength of heart muscle contractions.

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Negative Inotrope

When a substance decreases the strength of heart muscle contractions.

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Muscle Tone

The ability of a muscle to contract and relax.

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Press Markings

A characteristic of a leaf showing faint traces of the pressure applied during its growth.

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Midvein of Leaflets

The central vein running through a leaflet, visible due to differing amounts of chlorophyll.

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Chemical Tests

A chemical test used to identify specific compounds in a sample, often involving a color change.

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Methanolic Magnesium Acetate Test - Daylight

A test using an ether extract of hydrolysed acid solution of the drug, resulting in a pink color in daylight and a pale greenish-orange color in filtered ultraviolet light.

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Methanolic Magnesium Acetate Test - Filtered UV

A test using an ether extract of hydrolysed acid solution of the drug, resulting in an orange color in daylight and a yellowish-green color in filtered ultraviolet light.

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Digitalis leaf shape

Digitalis leaves are typically characterized by their shape, which is a combination of oval and lance-shaped, and they have a stem connecting them to the plant.

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Digitalis leaf length

The average length of Digitalis leaves ranges from 10 to 30 centimeters, making them relatively large.

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Digitalis leaf width

The width of a typical Digitalis leaf is between 4 to 10 centimeters, slightly narrower than the length.

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Digitalis leaf attachment

Digitalis leaves are attached to the plant by a petiole, a stalk that connects the leaf blade to the stem.

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Digitalis production locations

Digitalis leaves are produced commercially in Holland and Eastern Europe, indicating these regions are major suppliers of the plant.

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Study Notes

Pharmacognosy - Leaves

  • Leaves are lateral outgrowths from stems, typically flattened
  • Leaves consist of three main parts: leaf base, blade (lamina), and stalk (petiole)
  • Leaf blade's lamina is typically expanded and widest at its broadest portion
  • Different types of leaves exist (e.g., petiolate, sessile, stipulate, ex-stipulate) depending on the presence/absence of petiole and stipules.
  • Cotyledons (seed leaves) store food reserves (proteins)
  • Prophylls are simpler in form and structure than regular green leaves
  • Foliage leaves carry out normal leaf functions
  • Scale leaves are thin, membranous, and lack chlorophyll, often found on subterranean stems or some aerial stems.
  • Bracts are leaves with flowers or groups of flowers in their axils
  • Modified leaves can be modified into different structures for specific functions, such as tendrils (e.g., peas), spines (e.g., orange), traps for insects (e.g., sundews), or water storage (e.g., some succulents).

Phyllotaxis

  • Phyllotaxis is the arrangement of leaves on a stem
  • Alternate (Spiral): leaves are inserted singly at nodes at regular intervals
  • Opposite: a pair of leaves is developed at each node, opposite to each other
  • Opposite decussate: opposite leaves are inserted at right angles to the pair above and below
  • Whorled: three or more leaves occur at a single node

Leaf Base

  • Stipules are lateral outgrowths from the leaf base
  • Stipulate: leaves with stipules
  • Exstipulate: leaves without stipules

Lamina (Leaf Blade)

  • Simple leaf: continuous, undivided surface; without lobes or divisions
  • Lobed leaf: lamina cut divided into lobes connected by undivided portions
  • Pinnately lobed: incisions directed towards the midrib
  • Palmately lobed: incisions directed towards the petiole's top
  • Compound leaf: lamina divided into separate leaflets.
  • Types of compound leaves: Binate (2 leaflets), Ternate (3 leaflets), Pinnate, and Palmate.

Shape of Lamina

  • Filiform: thread-like
  • Acicular: tube-like (needle-shaped)
  • Tubular: tube-like (e.g., onion)
  • Linear: flat, edges generally parallel near the midline
  • Ovate: egg-shaped, widest portion near the base
  • Lanceolate: narrow, gradually tapering to the tip
  • Obvate: inverted ovate

Apex of Lamina

  • Acute: sharply pointed at the tip
  • Acuminate: tapering to a sharp point
  • Obtuse: rounded or blunt tip
  • Mucronate: abruptly pointed tip
  • Recurved: bent or curved backward
  • Emarginate: notched at the tip

Margin of Lamina

  • Entire: smooth margin
  • Crenate: rounded teeth
  • Denate: straight teeth, pointed outwards
  • Serrate: saw-toothed (teeth pointed towards apex) - Ciliate: fringed with hairs

Base of Lamina

  • Symmetric: equal on both sides
  • Asymmetric: unequal on both sides
  • Decurrent: continuous downwards like wings along the base.
  • Cordate : heart-shaped

Venation

  • Parallel: Veins run parallel to the margin
  • Pinnate: single main vein with smaller veins branching off
  • Palmate: several main veins departing from the petiole at the apex

Leaf Surface

  • Glabrous: smooth, free from hairs
  • Pubescent: hairy
  • Punctate: dotted with oil glands

Senna Leaf

  • Senna leaflets are the dried leaflets of Cassia senna
  • Senna is used as a laxative
  • Senna leaves are collected and prepared for use and export.

Belladonna Leaf

  • Belladonna consists of the dried leaves of Atropa belladonna
  • Belladonna is used for spastic conditions of stomach and intestine

Digitalis Leaf

  • Digitalis consists of the dried leaves of Digitalis purpurea
  • Digitalis is used in cases of cardiac failure.

Stramonium Leaf

  • Stramonium leaf consists of the dried leaves of Datura stramonium and its varieties
  • Stramonium leaf is used to control motion sickness

Buchu Leaf

  • Buchu is the dried leaves of Agathosma betulina
  • Buchu is traditionally used as a urinary antiseptic.

Boldo Leaf

  • Boldo is the dried leaves of Peumus boldus Molina
  • Boldo is used for gallstones, liver, stomach, and digestive issues.

Jaborandi Leaf

  • Jaborandi is the dried leaflets of Pilocarpus microphyllus
  • Jaborandi is used ophthalmically in glaucoma treatments.

Henna Leaf

  • Henna consists of the dried leaves of Lawsonia inermis
  • Henna is used as a hair dye.

Bearberry Leaf

  • Bearberry is the dried leaves of Arctostaphylos uva ursi
  • Bearberry is used for urinary infections

Green and Black Tea

  • Tea consists of the prepared leaves of Thea sinensis
  • Used for antioxidant activities and protecting against cancer and tooth decay

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