Pharmacogenomics and Pharmacogenetics Quiz
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Questions and Answers

Which term is used interchangeably with pharmacogenomics?

  • Pharmacodynamics
  • Pharmacokinetics
  • Metabolomics
  • Pharmacogenetics (correct)

What can vary between individuals due to genetic differences in drug metabolizing enzymes?

  • Drug dosage
  • Drug availability
  • Drug formulation
  • Drug response (correct)

What is the implication of being a 'fast' metabolizer of certain drugs?

  • Lower plasma concentrations of the parent drug, Lower concentrations of the metabolite
  • Lower plasma concentrations of the parent drug, Higher concentrations of the metabolite (correct)
  • Higher plasma concentrations of the parent drug, Higher concentrations of the metabolite
  • No effect on plasma concentrations

What is the implication of being a 'slow' metabolizer of certain drugs?

<p>Higher plasma concentrations of the parent drug, Lower concentrations of the metabolite (C)</p> Signup and view all the answers

What can being a 'slow' metabolizer of certain drugs lead to?

<p>Exaggerated therapeutic response at normal doses (C)</p> Signup and view all the answers

What is pharmacogenomics?

<p>The study of the genomic basis of why individuals vary in their response to drugs (C)</p> Signup and view all the answers

What is the relationship between race/ethnicity and pharmacokinetic parameters?

<p>Certain drugs show a bimodal distribution of pharmacokinetic parameters within a population (C)</p> Signup and view all the answers

What can genetic factors in drug metabolism have implications for?

<p>Therapeutic efficacy and/or toxicity of certain drugs (C)</p> Signup and view all the answers

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