16 Questions
DeoxyriboNucleic Acid (DNA) contains the purines Guanine(G) and Adenine(A)
True
The Central Dogma states that DNA is transcribed into RNA, which is translated into protein
True
Variations in DNA are called mutations
True
Genetic polymorphisms can influence drug disposition and response
True
About three quarters of whites and half of blacks have an inability to express functional CYP3A5 enzyme
True
A small change in the gene sequence can result in a very different protein
True
Cytosine (C) is a pyrimidine found in DNA
True
Thymine (T) is a purine found in DNA
False
The lack of functional CYP3A5 may not be readily evident due to the presence of CYP3A4, which can also metabolize many medications
True
More than 30 families of drug-metabolizing enzymes in humans are known, including the CYP-450 enzymes
True
Pharmacogenomics focuses on the role of genetics in drug responses
True
The Human Genome Project was completed in 1984
False
Genetic variations can affect appearance, behavior, susceptibility to disease, and response to medications
True
The Human Genome Project revealed about 20,500 human genes
True
Pharmacogenomics integrates molecular biology, pharmacology, therapeutics, and toxicology
True
Individual genetic variations have no impact on drug response
False
Learn about the role of individual genetic variations in drug response and the shift from one size fits all medicine to personalized medicine. Explore the goals, definitions, and integration of molecular biology, pharmacology, therapeutics, and toxicology in pharmacogenomics.
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