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Questions and Answers
DeoxyriboNucleic Acid (DNA) contains the purines Guanine(G) and Adenine(A)
DeoxyriboNucleic Acid (DNA) contains the purines Guanine(G) and Adenine(A)
True
The Central Dogma states that DNA is transcribed into RNA, which is translated into protein
The Central Dogma states that DNA is transcribed into RNA, which is translated into protein
True
Variations in DNA are called mutations
Variations in DNA are called mutations
True
Genetic polymorphisms can influence drug disposition and response
Genetic polymorphisms can influence drug disposition and response
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About three quarters of whites and half of blacks have an inability to express functional CYP3A5 enzyme
About three quarters of whites and half of blacks have an inability to express functional CYP3A5 enzyme
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A small change in the gene sequence can result in a very different protein
A small change in the gene sequence can result in a very different protein
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Cytosine (C) is a pyrimidine found in DNA
Cytosine (C) is a pyrimidine found in DNA
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Thymine (T) is a purine found in DNA
Thymine (T) is a purine found in DNA
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The lack of functional CYP3A5 may not be readily evident due to the presence of CYP3A4, which can also metabolize many medications
The lack of functional CYP3A5 may not be readily evident due to the presence of CYP3A4, which can also metabolize many medications
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More than 30 families of drug-metabolizing enzymes in humans are known, including the CYP-450 enzymes
More than 30 families of drug-metabolizing enzymes in humans are known, including the CYP-450 enzymes
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Pharmacogenomics focuses on the role of genetics in drug responses
Pharmacogenomics focuses on the role of genetics in drug responses
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The Human Genome Project was completed in 1984
The Human Genome Project was completed in 1984
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Genetic variations can affect appearance, behavior, susceptibility to disease, and response to medications
Genetic variations can affect appearance, behavior, susceptibility to disease, and response to medications
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The Human Genome Project revealed about 20,500 human genes
The Human Genome Project revealed about 20,500 human genes
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Pharmacogenomics integrates molecular biology, pharmacology, therapeutics, and toxicology
Pharmacogenomics integrates molecular biology, pharmacology, therapeutics, and toxicology
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Individual genetic variations have no impact on drug response
Individual genetic variations have no impact on drug response
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