Podcast
Questions and Answers
Which population is the HLA-B*1502 test effective for?
Which population is the HLA-B*1502 test effective for?
- African descent populations
- All populations
- European descent populations
- Asian descent populations (correct)
What is the major cause of toxic epidermal necrolysis (TEN)?
What is the major cause of toxic epidermal necrolysis (TEN)?
- Adverse effect of pharmaceuticals (correct)
- Infection
- Genetic mutation
- Environmental factors
What is the incidence rate of toxic epidermal necrolysis (TEN) per million population per year?
What is the incidence rate of toxic epidermal necrolysis (TEN) per million population per year?
- 15-20
- 1-5 (correct)
- 10-15
- 5-10
Which enzyme is responsible for the conversion of codeine to morphine in the body?
Which enzyme is responsible for the conversion of codeine to morphine in the body?
What is the clinical relevance of genetic variation in drug metabolizing enzymes?
What is the clinical relevance of genetic variation in drug metabolizing enzymes?
What is the role of CYP2D6 in the metabolism of tamoxifen?
What is the role of CYP2D6 in the metabolism of tamoxifen?
Which phase of metabolism is responsible for introducing functional groups such as -OH, -NH2, -COOH into a drug molecule?
Which phase of metabolism is responsible for introducing functional groups such as -OH, -NH2, -COOH into a drug molecule?
Which enzyme is involved in the metabolism of more than 75% of drugs in use?
Which enzyme is involved in the metabolism of more than 75% of drugs in use?
Which gene is a good candidate gene for the metabolism of Mercaptopurine (Purinethol) and azathioprine?
Which gene is a good candidate gene for the metabolism of Mercaptopurine (Purinethol) and azathioprine?
Which gene influences enzyme activity and has different genotypes with varying enzyme activity levels?
Which gene influences enzyme activity and has different genotypes with varying enzyme activity levels?
