Medical Genetics Lectures on Cells and Microbiome
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Questions and Answers

Match the following with their respective descriptions:

Somatic cells = Cells that make your organs and tissues Germ Cells = The ONLY cells that are not somatic – sperm and egg (Gametes) Meiosis = Includes two nuclear divisions Mitosis = Preceded by one round of DNA replication

Match the following with their respective characteristics:

Human Microbiome = Cells within and on us that are not actually of us, constitute the human microbiome 2n Cells = Division preceded by one round of DNA replication mtDNA = Genetic material present in a Human cell nDNA = Arranged on multiple chromosomes; twenty three pairs of chromosomes

Match the following with their respective quantities:

30 trillion cells = Average number of cells in a human body 39 trillion cells/particles = Number of bacterial, fungal, or protozoan cells in a healthy human body 23 pairs of chromosome = Number of chromosome pairs in every human cell (except mature red blood cells) Half the normal complement of chromosomes = Complement of chromosomes in gametes or sex cells (sperm and eggs)

Match the following with their respective genetic distinctions:

<p>Meiosis daughter cells = Haploid and genetically distinct Mitosis daughter cells = Diploid and identical to the parent cell Human Genome = All genetic material of Human</p> Signup and view all the answers

Match the following cell types with their respective descriptions:

<p>Cells Smallest living unit = Cell Types Somatic cells = Cells that make your organs and tissues Germ Cells = The ONLY cells that are not somatic – sperm and egg (Gametes) 2n Cells = Division preceded by one round of DNA replication</p> Signup and view all the answers

Match the DNA component with its description:

<p>mtDNA = Forms closed circular molecules Chromatin = Composed of a nucleosome array condensed into about 30 nm fiber Genome = Contains over 3 billion base pairs or nucleotides Gene = A piece of DNA that encodes a particular trait</p> Signup and view all the answers

Match the chromatin type with its characteristic structure:

<p>Euchromatin = Less compact structure, often described as an 11 nm fiber with the appearance of ‘beads on a string’ Heterochromatin = More compact structure, often reported as being composed of a nucleosome array condensed into about 30 nm fiber Interphase Chromatin = Classified as either euchromatin or heterochromatin based on its level of compaction Metaphase Chromosomes = Consist of two identical sister chromatids formed through chromatin condensation</p> Signup and view all the answers

Match the genetic term with its definition:

<p>Allele = An alternate form of a gene Phenotype = The physical expression of a gene or allele Genotype = The genetic composition of an individual Locus = The location of a gene</p> Signup and view all the answers

Match the genetic process with its description:

<p>Genes transcription = Process of transcribing DNA into RNA DNA replication = Process of replicating cellular DNA during interphase Translation = Process of translating RNA into protein Gregor Mendel = Associated with Genetics and Blood Group Systems</p> Signup and view all the answers

Match the biological concept with its definition:

<p>Karyotype = Visual representation of an individual's chromosomes Non-Coding DNA = Comprised of non-coding sequences in the human genome The “Central Dogma” = Flow of genetic information in a cell from genes to proteins Mitosis = Cellular process involving chromosome condensation and division</p> Signup and view all the answers

Germ cells are the only cells that are somatic.

<p>False</p> Signup and view all the answers

The human microbiome consists of about 30 trillion bacterial, fungal, or protozoan cells.

<p>False</p> Signup and view all the answers

Meiosis includes only one nuclear division.

<p>False</p> Signup and view all the answers

The daughter cells resulting from mitosis are haploid and genetically distinct.

<p>False</p> Signup and view all the answers

Human genome refers to the complete set of genes present in a human cell.

<p>True</p> Signup and view all the answers

Mitochondrial DNA forms linear molecules.

<p>False</p> Signup and view all the answers

Euchromatin is more compact than heterochromatin.

<p>False</p> Signup and view all the answers

Chromatin condensation leads to the formation of metaphase chromosomes during interphase.

<p>False</p> Signup and view all the answers

The human genome contains over 20,000 genes.

<p>True</p> Signup and view all the answers

A gene encodes a genetic trait, while an allele represents the physical expression of that trait.

<p>False</p> Signup and view all the answers

Study Notes

Cell Types and Genetics

  • Germ cells are not somatic cells; they are the reproductive cells that give rise to gametes (sperm or egg cells).
  • The human microbiome comprises approximately 30 trillion microbial cells, including bacteria, fungi, and protozoa.

Cell Division

  • Meiosis involves two nuclear divisions, resulting in four haploid daughter cells that are genetically unique.
  • Mitosis produces two diploid daughter cells that are genetically identical to the parent cell.

DNA and Chromatin

  • The human genome refers to the complete set of genes present in a human cell, estimated to be over 20,000 genes.
  • Mitochondrial DNA forms circular molecules, not linear molecules.
  • Euchromatin is less compact than heterochromatin.
  • Chromatin condensation leads to the formation of metaphase chromosomes during the mitotic phase, not interphase.

Genetic Concepts

  • A gene encodes a genetic trait, while an allele represents a specific variant of that gene.
  • Haploid cells have a single set of chromosomes, whereas diploid cells have two sets of chromosomes.

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Test your knowledge about cells, including somatic cells, germ cells, mitosis, meiosis, and the human microbiome. Explore the concepts of human cells and the vast ecosystems for microscopic life within the body.

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