Pharmacodynamics: Mechanism of Drug Action

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10 Questions

Which drug acts by physical means?

Mannitol

Which drug is used in the treatment of Wilson’s disease by chelating copper?

Penicillamine

Which drug antagonizes heparin?

Protamine

Which drug increases the permeability of bacterial plasma membrane?

Polymixins

Which drug is used to chelate calcium, lead, and digitalis?

EDTA

Which drug is mainly employed in the treatment of heavy metal poisoning?

EDTA

Which drug is employed in the treatment of Wilson’s disease by chelating copper?

Penicillamine

Which drug binds to 30 S ribosomal subunit to inhibit protein synthesis in bacteria?

Tetracyclines

Which drug antagonizes heparin through its alkaline and positive charge properties?

Protamine

Which drug is used to chelate arsenic, mercury, and copper?

Dimercaprol (BAL)

Study Notes

Pharmacology of Various Drugs

  • Sucralfate acts by physical means.

Treatment of Wilson's Disease

  • Penicillamine is used in the treatment of Wilson's disease by chelating copper.

Antagonists of Heparin

  • Protamine antagonizes heparin.

Antibacterial Mechanisms

  • Polymyxin increases the permeability of bacterial plasma membrane.

Chelating Agents

  • EDTA is used to chelate calcium, lead, and digitalis.
  • Dimercaprol is mainly employed in the treatment of heavy metal poisoning.
  • Penicillamine is employed in the treatment of Wilson's disease by chelating copper.

Antibiotics

  • Tetracycline binds to 30 S ribosomal subunit to inhibit protein synthesis in bacteria.

Anticoagulant Antagonists

  • Protamine antagonizes heparin through its alkaline and positive charge properties.

Chelating Agents

  • Dimercaprol is used to chelate arsenic, mercury, and copper.

Explore the principles of pharmacodynamics with Dr. Ghada Samy and learn about the biochemical and pharmacological effects of drugs, as well as their mechanisms of action. This lecture covers non-receptor mediated drug actions through chemical and physical means, providing valuable insights into drug interactions and effects on the body.

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